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Results: 1 to 20 of 31


Fitting the Balding-Nichols model to forensic databases.

Rohlfs RV, Aguiar VR, Lohmueller KE, Castro AM, Ferreira AC, Almeida VC, Louro ID, Nielsen R.

Forensic Sci Int Genet. 2015 Jun 23;19:86-91. doi: 10.1016/j.fsigen.2015.05.005. [Epub ahead of print]


Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders.

Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B.

Eur J Hum Genet. 2015 Apr 22. doi: 10.1038/ejhg.2015.68. [Epub ahead of print]


Selection and reduced population size cannot explain higher amounts of Neandertal ancestry in East Asian than in European human populations.

Kim BY, Lohmueller KE.

Am J Hum Genet. 2015 Mar 5;96(3):454-61. doi: 10.1016/j.ajhg.2014.12.029. Epub 2015 Feb 12.


The distribution of deleterious genetic variation in human populations.

Lohmueller KE.

Curr Opin Genet Dev. 2014 Dec;29:139-46.


Evolution. On the origin of Peter Rabbit.

Lohmueller KE.

Science. 2014 Aug 29;345(6200):1000-1. doi: 10.1126/science.1258775. No abstract available.


A model-based approach for identifying signatures of ancient balancing selection in genetic data.

DeGiorgio M, Lohmueller KE, Nielsen R.

PLoS Genet. 2014 Aug 21;10(8):e1004561. doi: 10.1371/journal.pgen.1004561. eCollection 2014 Aug.


Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.

Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P.

Nat Commun. 2014 Jun 2;5:3983. doi: 10.1038/ncomms4983.


The impact of population demography and selection on the genetic architecture of complex traits.

Lohmueller KE.

PLoS Genet. 2014 May 29;10(5):e1004379. doi: 10.1371/journal.pgen.1004379. eCollection 2014.


Analysis of allelic drop-out using the Identifiler(®) and PowerPlex(®) 16 forensic STR typing systems.

Lohmueller KE, Rudin N, Inman K.

Forensic Sci Int Genet. 2014 Sep;12:1-11. doi: 10.1016/j.fsigen.2014.04.003. Epub 2014 Apr 18.


Natural selection reduced diversity on human y chromosomes.

Wilson Sayres MA, Lohmueller KE, Nielsen R.

PLoS Genet. 2014 Jan;10(1):e1004064. doi: 10.1371/journal.pgen.1004064. Epub 2014 Jan 9.


Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.

Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, Degiorgio M, Jørgensen T, Sandbæk A, Lauritzen T, Brunak S, Kristiansen K, Li Y, Hansen T, Wang J, Nielsen R, Pedersen O.

Am J Hum Genet. 2013 Dec 5;93(6):1072-86. doi: 10.1016/j.ajhg.2013.11.005. Epub 2013 Nov 27. Erratum in: Am J Hum Genet. 2014 Mar 6;94(3):479.


Calculating the weight of evidence in low-template forensic DNA casework.

Lohmueller KE, Rudin N.

J Forensic Sci. 2013 Jan;58 Suppl 1:S243-9. doi: 10.1111/1556-4029.12017. Epub 2012 Oct 19.


Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

Lohmueller KE, Albrechtsen A, Li Y, Kim SY, Korneliussen T, Vinckenbosch N, Tian G, Huerta-Sanchez E, Feder AF, Grarup N, Jørgensen T, Jiang T, Witte DR, Sandbæk A, Hellmann I, Lauritzen T, Hansen T, Pedersen O, Wang J, Nielsen R.

PLoS Genet. 2011 Oct;7(10):e1002326. doi: 10.1371/journal.pgen.1002326. Epub 2011 Oct 13.


An Aboriginal Australian genome reveals separate human dispersals into Asia.

Rasmussen M, Guo X, Wang Y, Lohmueller KE, Rasmussen S, Albrechtsen A, Skotte L, Lindgreen S, Metspalu M, Jombart T, Kivisild T, Zhai W, Eriksson A, Manica A, Orlando L, De La Vega FM, Tridico S, Metspalu E, Nielsen K, Ávila-Arcos MC, Moreno-Mayar JV, Muller C, Dortch J, Gilbert MT, Lund O, Wesolowska A, Karmin M, Weinert LA, Wang B, Li J, Tai S, Xiao F, Hanihara T, van Driem G, Jha AR, Ricaut FX, de Knijff P, Migliano AB, Gallego Romero I, Kristiansen K, Lambert DM, Brunak S, Forster P, Brinkmann B, Nehlich O, Bunce M, Richards M, Gupta R, Bustamante CD, Krogh A, Foley RA, Lahr MM, Balloux F, Sicheritz-Pontén T, Villems R, Nielsen R, Wang J, Willerslev E.

Science. 2011 Oct 7;334(6052):94-8. doi: 10.1126/science.1211177. Epub 2011 Sep 22.


Estimation of allele frequency and association mapping using next-generation sequencing data.

Kim SY, Lohmueller KE, Albrechtsen A, Li Y, Korneliussen T, Tian G, Grarup N, Jiang T, Andersen G, Witte D, Jorgensen T, Hansen T, Pedersen O, Wang J, Nielsen R.

BMC Bioinformatics. 2011 Jun 11;12:231. doi: 10.1186/1471-2105-12-231.


Detecting directional selection in the presence of recent admixture in African-Americans.

Lohmueller KE, Bustamante CD, Clark AG.

Genetics. 2011 Mar;187(3):823-35. doi: 10.1534/genetics.110.122739. Epub 2010 Dec 31.


A simple genetic architecture underlies morphological variation in dogs.

Boyko AR, Quignon P, Li L, Schoenebeck JJ, Degenhardt JD, Lohmueller KE, Zhao K, Brisbin A, Parker HG, vonHoldt BM, Cargill M, Auton A, Reynolds A, Elkahloun AG, Castelhano M, Mosher DS, Sutter NB, Johnson GS, Novembre J, Hubisz MJ, Siepel A, Wayne RK, Bustamante CD, Ostrander EA.

PLoS Biol. 2010 Aug 10;8(8):e1000451. doi: 10.1371/journal.pbio.1000451.


Sex-averaged recombination and mutation rates on the X chromosome: a comment on Labuda et al.

Lohmueller KE, Degenhardt JD, Keinan A.

Am J Hum Genet. 2010 Jun 11;86(6):978-80; author reply 980-1. doi: 10.1016/j.ajhg.2010.03.021. No abstract available.


Graydon et al. provide no new evidence that forensic STR loci are functional.

Lohmueller KE.

Forensic Sci Int Genet. 2010 Jul;4(4):273-4. doi: 10.1016/j.fsigen.2009.09.006. Epub 2009 Oct 2.


The effect of recent admixture on inference of ancient human population history.

Lohmueller KE, Bustamante CD, Clark AG.

Genetics. 2010 Jun;185(2):611-22. doi: 10.1534/genetics.109.113761. Epub 2010 Apr 9.

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