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Items: 1 to 20 of 38

1.

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species.

Phung TN, Huber CD, Lohmueller KE.

PLoS Genet. 2016 Aug 10;12(8):e1006199. doi: 10.1371/journal.pgen.1006199. eCollection 2016 Aug.

2.

PReFerSim: fast simulation of demography and selection under the Poisson Random Field model.

Ortega-Del Vecchyo D, Marsden CD, Lohmueller KE.

Bioinformatics. 2016 Jul 19. pii: btw478. [Epub ahead of print]

PMID:
27436562
3.

Genomic Flatlining in the Endangered Island Fox.

Robinson JA, Ortega-Del Vecchyo D, Fan Z, Kim BY, vonHoldt BM, Marsden CD, Lohmueller KE, Wayne RK.

Curr Biol. 2016 May 9;26(9):1183-9. doi: 10.1016/j.cub.2016.02.062. Epub 2016 Apr 21.

PMID:
27112291
4.

An assessment of the information content of likelihood ratios derived from complex mixtures.

Marsden CD, Rudin N, Inman K, Lohmueller KE.

Forensic Sci Int Genet. 2016 May;22:64-72. doi: 10.1016/j.fsigen.2016.01.008. Epub 2016 Jan 19.

PMID:
26851613
5.

Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs.

Marsden CD, Ortega-Del Vecchyo D, O'Brien DP, Taylor JF, Ramirez O, Vilà C, Marques-Bonet T, Schnabel RD, Wayne RK, Lohmueller KE.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):152-7. doi: 10.1073/pnas.1512501113. Epub 2015 Dec 22.

6.

Lab Retriever: a software tool for calculating likelihood ratios incorporating a probability of drop-out for forensic DNA profiles.

Inman K, Rudin N, Cheng K, Robinson C, Kirschner A, Inman-Semerau L, Lohmueller KE.

BMC Bioinformatics. 2015 Sep 18;16:298. doi: 10.1186/s12859-015-0740-8.

7.

Height-reducing variants and selection for short stature in Sardinia.

Zoledziewska M, Sidore C, Chiang CW, Sanna S, Mulas A, Steri M, Busonero F, Marcus JH, Marongiu M, Maschio A, Del Vecchyo DO, Floris M, Meloni A, Delitala A, Concas MP, Murgia F, Biino G, Vaccargiu S, Nagaraja R, Lohmueller KE; UK10K Consortium, Timpson NJ, Soranzo N, Tachmazidou I, Dedoussis G, Zeggini E; Understanding Society Scientific Group, Uzzau S, Jones C, Lyons R, Angius A, Abecasis GR, Novembre J, Schlessinger D, Cucca F.

Nat Genet. 2015 Nov;47(11):1352-6. doi: 10.1038/ng.3403. Epub 2015 Sep 14.

8.

Fitting the Balding-Nichols model to forensic databases.

Rohlfs RV, Aguiar VR, Lohmueller KE, Castro AM, Ferreira AC, Almeida VC, Louro ID, Nielsen R.

Forensic Sci Int Genet. 2015 Nov;19:86-91. doi: 10.1016/j.fsigen.2015.05.005. Epub 2015 Jun 23.

PMID:
26186694
9.

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders.

Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B.

Eur J Hum Genet. 2016 Jan;24(1):113-9. doi: 10.1038/ejhg.2015.68. Epub 2015 Apr 22.

PMID:
25898925
10.

Selection and reduced population size cannot explain higher amounts of Neandertal ancestry in East Asian than in European human populations.

Kim BY, Lohmueller KE.

Am J Hum Genet. 2015 Mar 5;96(3):454-61. doi: 10.1016/j.ajhg.2014.12.029. Epub 2015 Feb 12.

11.

The distribution of deleterious genetic variation in human populations.

Lohmueller KE.

Curr Opin Genet Dev. 2014 Dec;29:139-46. Review.

PMID:
25461617
12.

Evolution. On the origin of Peter Rabbit.

Lohmueller KE.

Science. 2014 Aug 29;345(6200):1000-1. doi: 10.1126/science.1258775. No abstract available.

PMID:
25170135
13.

A model-based approach for identifying signatures of ancient balancing selection in genetic data.

DeGiorgio M, Lohmueller KE, Nielsen R.

PLoS Genet. 2014 Aug 21;10(8):e1004561. doi: 10.1371/journal.pgen.1004561. eCollection 2014 Aug.

14.

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.

Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P.

Nat Commun. 2014 Jun 2;5:3983. doi: 10.1038/ncomms4983.

15.

The impact of population demography and selection on the genetic architecture of complex traits.

Lohmueller KE.

PLoS Genet. 2014 May 29;10(5):e1004379. doi: 10.1371/journal.pgen.1004379. eCollection 2014.

16.

Analysis of allelic drop-out using the Identifiler(®) and PowerPlex(®) 16 forensic STR typing systems.

Lohmueller KE, Rudin N, Inman K.

Forensic Sci Int Genet. 2014 Sep;12:1-11. doi: 10.1016/j.fsigen.2014.04.003. Epub 2014 Apr 18.

PMID:
24841801
17.

Natural selection reduced diversity on human y chromosomes.

Wilson Sayres MA, Lohmueller KE, Nielsen R.

PLoS Genet. 2014 Jan;10(1):e1004064. doi: 10.1371/journal.pgen.1004064. Epub 2014 Jan 9.

18.

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.

Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, Degiorgio M, Jørgensen T, Sandbæk A, Lauritzen T, Brunak S, Kristiansen K, Li Y, Hansen T, Wang J, Nielsen R, Pedersen O.

Am J Hum Genet. 2013 Dec 5;93(6):1072-86. doi: 10.1016/j.ajhg.2013.11.005. Epub 2013 Nov 27. Erratum in: Am J Hum Genet. 2014 Mar 6;94(3):479.

19.

Calculating the weight of evidence in low-template forensic DNA casework.

Lohmueller KE, Rudin N.

J Forensic Sci. 2013 Jan;58 Suppl 1:S243-9. doi: 10.1111/1556-4029.12017. Epub 2012 Oct 19.

PMID:
23082963
20.

Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

Lohmueller KE, Albrechtsen A, Li Y, Kim SY, Korneliussen T, Vinckenbosch N, Tian G, Huerta-Sanchez E, Feder AF, Grarup N, Jørgensen T, Jiang T, Witte DR, Sandbæk A, Hellmann I, Lauritzen T, Hansen T, Pedersen O, Wang J, Nielsen R.

PLoS Genet. 2011 Oct;7(10):e1002326. doi: 10.1371/journal.pgen.1002326. Epub 2011 Oct 13.

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