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Items: 1 to 20 of 209


Cross-Talk between Epithelial Cells and Type 2 Immune Signaling. The Role of IL-25.

Gordon ED, Locksley RM, Fahy JV.

Am J Respir Crit Care Med. 2016 May 1;193(9):935-6. doi: 10.1164/rccm.201512-2534ED. No abstract available.


Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit.

von Moltke J, Ji M, Liang HE, Locksley RM.

Nature. 2016 Jan 14;529(7585):221-5. doi: 10.1038/nature16161. Epub 2015 Dec 14.


Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis.

Mohapatra A, Van Dyken SJ, Schneider C, Nussbaum JC, Liang HE, Locksley RM.

Mucosal Immunol. 2016 Jan;9(1):275-86. doi: 10.1038/mi.2015.59. Epub 2015 Jul 1.


Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation.

Molofsky AB, Van Gool F, Liang HE, Van Dyken SJ, Nussbaum JC, Lee J, Bluestone JA, Locksley RM.

Immunity. 2015 Jul 21;43(1):161-74. doi: 10.1016/j.immuni.2015.05.019. Epub 2015 Jun 16.


Interleukin-33 in Tissue Homeostasis, Injury, and Inflammation.

Molofsky AB, Savage AK, Locksley RM.

Immunity. 2015 Jun 16;42(6):1005-19. doi: 10.1016/j.immuni.2015.06.006. Review.


New blood: Creative funding of disease-specific research.

Seaman WE, Locksley RM, Welsh MJ.

Sci Transl Med. 2015 May 20;7(288):288ed5. doi: 10.1126/scitranslmed.aaa9513. No abstract available.


IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function.

Cheng LE, Sullivan BM, Retana LE, Allen CD, Liang HE, Locksley RM.

J Exp Med. 2015 Apr 6;212(4):513-24. doi: 10.1084/jem.20141671. Epub 2015 Mar 16.


A novel model for IFN-γ-mediated autoinflammatory syndromes.

Reinhardt RL, Liang HE, Bao K, Price AE, Mohrs M, Kelly BL, Locksley RM.

J Immunol. 2015 Mar 1;194(5):2358-68. doi: 10.4049/jimmunol.1401992. Epub 2015 Jan 30.


Activated type 2 innate lymphoid cells regulate beige fat biogenesis.

Lee MW, Odegaard JI, Mukundan L, Qiu Y, Molofsky AB, Nussbaum JC, Yun K, Locksley RM, Chawla A.

Cell. 2015 Jan 15;160(1-2):74-87. doi: 10.1016/j.cell.2014.12.011. Epub 2014 Dec 24.


Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine.

Bando JK, Liang HE, Locksley RM.

Nat Immunol. 2015 Feb;16(2):153-60. doi: 10.1038/ni.3057. Epub 2014 Dec 15.


I-L-C-2 it: type 2 immunity and group 2 innate lymphoid cells in homeostasis.

von Moltke J, Locksley RM.

Curr Opin Immunol. 2014 Dec;31:58-65. doi: 10.1016/j.coi.2014.09.009. Epub 2014 Oct 13. Review.


Allergic inflammation--innately homeostatic.

Cheng LE, Locksley RM.

Cold Spring Harb Perspect Biol. 2014 Nov 20;7(3):a016352. doi: 10.1101/cshperspect.a016352. Review.


Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy.

Van Gool F, Molofsky AB, Morar MM, Rosenzwajg M, Liang HE, Klatzmann D, Locksley RM, Bluestone JA.

Blood. 2014 Dec 4;124(24):3572-6. doi: 10.1182/blood-2014-07-587493. Epub 2014 Oct 16.


Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.

Qiu Y, Nguyen KD, Odegaard JI, Cui X, Tian X, Locksley RM, Palmiter RD, Chawla A.

Cell. 2014 Jun 5;157(6):1292-308. doi: 10.1016/j.cell.2014.03.066.


Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.

Patnode ML, Bando JK, Krummel MF, Locksley RM, Rosen SD.

J Exp Med. 2014 Jun 30;211(7):1281-8. doi: 10.1084/jem.20132336. Epub 2014 Jun 2.


Eosinophils are recruited in response to chitin exposure and enhance Th2-mediated immune pathology in Aspergillus fumigatus infection.

O'Dea EM, Amarsaikhan N, Li H, Downey J, Steele E, Van Dyken SJ, Locksley RM, Templeton SP.

Infect Immun. 2014 Aug;82(8):3199-205. doi: 10.1128/IAI.01990-14. Epub 2014 May 19.


Asthma and the flu: a tricky two-step.

Locksley RM, Fahy JV.

Immunol Cell Biol. 2014 May-Jun;92(5):389-91. doi: 10.1038/icb.2014.24. Epub 2014 Apr 1. No abstract available.


Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and γδ T cells.

Van Dyken SJ, Mohapatra A, Nussbaum JC, Molofsky AB, Thornton EE, Ziegler SF, McKenzie AN, Krummel MF, Liang HE, Locksley RM.

Immunity. 2014 Mar 20;40(3):414-24. doi: 10.1016/j.immuni.2014.02.003. Epub 2014 Mar 13.


Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.

Hams E, Locksley RM, McKenzie AN, Fallon PG.

J Immunol. 2013 Dec 1;191(11):5349-53. doi: 10.4049/jimmunol.1301176. Epub 2013 Oct 28.


Type 2 innate lymphoid cells control eosinophil homeostasis.

Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM.

Nature. 2013 Oct 10;502(7470):245-8. doi: 10.1038/nature12526. Epub 2013 Sep 15.

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