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Items: 1 to 20 of 119


Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, Johns H, Karydas A, Knopman DS, Loboda A, Masliah E, Narasimhan R, Petersen RC, Podtelezhnikov A, Pradhan S, Rademakers R, Sun CH, Younkin SG, Miller BL, Ideker T, Wyss-Coray T.

Mol Neurodegener. 2016 Apr 26;11(1):31. doi: 10.1186/s13024-016-0095-2.


Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism.

Loboda A, Damulewicz M, Pyza E, Jozkowicz A, Dulak J.

Cell Mol Life Sci. 2016 Apr 21. [Epub ahead of print] Review.


GAM: a web-service for integrated transcriptional and metabolic network analysis.

Sergushichev AA, Loboda AA, Jha AK, Vincent EE, Driggers EM, Jones RG, Pearce EJ, Artyomov MN.

Nucleic Acids Res. 2016 Apr 20. pii: gkw266. [Epub ahead of print]


Influence of osteoclasts and osteoprotegerin on the mode of calcific degeneration of aortic valves.

Lis GJ, Czubek U, Jasek-Gajda E, Łoboda A, Dulak J, Nessler J, Kapelak B, Sadowski J, Litwin JA.

Pol Arch Med Wewn. 2016 Mar 22;126(3):149-58. doi: 10.20452/pamw.3326. Epub 2016 Mar 22.


An unbiased oncology compound screen to identify novel combination strategies.

O'Neil J, Benita Y, Feldman I, Chenard M, Roberts B, Liu Y, Li J, Kral A, Lejnine S, Loboda A, Arthur W, Cristescu R, Haines BB, Winter C, Zhang T, Bloecher A, Shumway SD.

Mol Cancer Ther. 2016 Mar 16. pii: molcanther.0843.2015. [Epub ahead of print]


An accessible pharmacodynamic transcriptional biomarker for notch target engagement.

Tanis KQ, Podtelezhnikov AA, Blackman SC, Hing J, Railkar RA, Lunceford J, Klappenbach JA, Wei B, Harman A, Camargo LM, Shah S, Finney EM, Hardwick JS, Loboda A, Watters J, Bergstrom DA, Demuth T, Herman GA, Strack PR, Iannone R.

Clin Pharmacol Ther. 2016 Apr;99(4):370-80. doi: 10.1002/cpt.335. Epub 2016 Feb 17.


Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination.

Fourati S, Cristescu R, Loboda A, Talla A, Filali A, Railkar R, Schaeffer AK, Favre D, Gagnon D, Peretz Y, Wang IM, Beals CR, Casimiro DR, Carayannopoulos LN, Sékaly RP.

Nat Commun. 2016 Jan 8;7:10369. doi: 10.1038/ncomms10369.


Effects of Long-Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate.

Muise ES, Podtelezhnikov AA, Pickarski M, Loboda A, Tan Y, Hu G, Thomspon JR, Duong le T.

J Bone Miner Res. 2016 Apr;31(4):839-51. doi: 10.1002/jbmr.2752. Epub 2016 Jan 8.


Letter by Loboda et al Regarding Article, "Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis": IL-8 Is Not Present in Murine Genome Hence it Cannot Be Responsible for the Bach1 Effect on Angiogenesis in Mice.

Loboda A, Florczyk U, Jazwa A, Grochot-Przeczek A, Nowak W, Jozkowicz A, Dulak J.

Circ Res. 2015 Oct 9;117(9):e75-6. doi: 10.1161/CIRCRESAHA.115.307450. No abstract available.


A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome.

Schell MJ, Yang M, Missiaglia E, Delorenzi M, Soneson C, Yue B, Nebozhyn MV, Loboda A, Bloom G, Yeatman TJ.

Clin Cancer Res. 2016 Feb 1;22(3):734-45. doi: 10.1158/1078-0432.CCR-15-0143. Epub 2015 Oct 7.


Clock and clock-controlled genes are differently expressed in the retina, lamina and in selected cells of the visual system of Drosophila melanogaster.

Damulewicz M, Loboda A, Bukowska-Strakova K, Jozkowicz A, Dulak J, Pyza E.

Front Cell Neurosci. 2015 Sep 15;9:353. doi: 10.3389/fncel.2015.00353. eCollection 2015.


A Randomized Phase II/III Study of Dalotuzumab in Combination With Cetuximab and Irinotecan in Chemorefractory, KRAS Wild-Type, Metastatic Colorectal Cancer.

Sclafani F, Kim TY, Cunningham D, Kim TW, Tabernero J, Schmoll HJ, Roh JK, Kim SY, Park YS, Guren TK, Hawkes E, Clarke SJ, Ferry D, Frödin JE, Ayers M, Nebozhyn M, Peckitt C, Loboda A, Mauro DJ, Watkins DJ.

J Natl Cancer Inst. 2015 Sep 23;107(12):djv258. doi: 10.1093/jnci/djv258. Print 2015 Dec.


HO-1/CO system in tumor growth, angiogenesis and metabolism - Targeting HO-1 as an anti-tumor therapy.

Loboda A, Jozkowicz A, Dulak J.

Vascul Pharmacol. 2015 Nov;74:11-22. doi: 10.1016/j.vph.2015.09.004. Epub 2015 Sep 25. Review.


Predicting Response to Histone Deacetylase Inhibitors Using High-Throughput Genomics.

Geeleher P, Loboda A, Lenkala D, Wang F, LaCroix B, Karovic S, Wang J, Nebozhyn M, Chisamore M, Hardwick J, Maitland ML, Huang RS.

J Natl Cancer Inst. 2015 Aug 21;107(11). pii: djv247. doi: 10.1093/jnci/djv247. Print 2015 Nov.


Carbon monoxide: pro- or anti-angiogenic agent? Comment on Ahmad et al. (Thromb Haemost 2015; 113: 329-337).

Loboda A, Jozkowicz A, Dulak J.

Thromb Haemost. 2015 Aug;114(2):432-3. doi: 10.1160/TH15-01-0082. Epub 2015 Apr 23. No abstract available.


Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.

Cristescu R, Lee J, Nebozhyn M, Kim KM, Ting JC, Wong SS, Liu J, Yue YG, Wang J, Yu K, Ye XS, Do IG, Liu S, Gong L, Fu J, Jin JG, Choi MG, Sohn TS, Lee JH, Bae JM, Kim ST, Park SH, Sohn I, Jung SH, Tan P, Chen R, Hardwick J, Kang WK, Ayers M, Hongyue D, Reinhard C, Loboda A, Kim S, Aggarwal A.

Nat Med. 2015 May;21(5):449-56. doi: 10.1038/nm.3850. Epub 2015 Apr 20.


Pre-treatment whole blood gene expression is associated with 14-week response assessed by dynamic contrast enhanced magnetic resonance imaging in infliximab-treated rheumatoid arthritis patients.

MacIsaac KD, Baumgartner R, Kang J, Loboda A, Peterfy C, DiCarlo J, Riek J, Beals C.

PLoS One. 2014 Dec 12;9(12):e113937. doi: 10.1371/journal.pone.0113937. eCollection 2014.


Comment on "role of microRNA-29b in the ochratoxin A-induced enhanced collagen formation in human kidney cells".

Loboda A, Jozkowicz A, Dulak J.

Toxicology. 2015 Feb 3;328:82-3. doi: 10.1016/j.tox.2014.12.002. Epub 2014 Dec 4. No abstract available.


Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.

Wong SS, Kim KM, Ting JC, Yu K, Fu J, Liu S, Cristescu R, Nebozhyn M, Gong L, Yue YG, Wang J, Ronghua C, Loboda A, Hardwick J, Liu X, Dai H, Jin JG, Ye XS, Kang SY, Do IG, Park JO, Sohn TS, Reinhard C, Lee J, Kim S, Aggarwal A.

Nat Commun. 2014 Nov 19;5:5477. doi: 10.1038/ncomms6477.


MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis.

Booher RN, Hatch H, Dolinski BM, Nguyen T, Harmonay L, Al-Assaad AS, Ayers M, Nebozhyn M, Loboda A, Hirsch HA, Zhang T, Shi B, Merkel CE, Angagaw MH, Wang Y, Long BJ, Lennon XQ, Miselis N, Pucci V, Monahan JW, Lee J, Kondic AG, Im EK, Mauro D, Blanchard R, Gilliland G, Fawell SE, Zawel L, Schuller AG, Strack P.

PLoS One. 2014 Oct 7;9(10):e108371. doi: 10.1371/journal.pone.0108371. eCollection 2014.

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