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Prevalence, diagnosis, and disease course of pertussis in adults with acute cough: a prospective, observational study in primary care.

Teepe J, Broekhuizen BD, Ieven M, Loens K, Huygen K, Kretzschmar M, de Melker H, Butler CC, Little P, Stuart B, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2015 Oct;65(639):e662-7. doi: 10.3399/bjgp15X686917.


Using an internet intervention to support self-management of low back pain in primary care: protocol for a randomised controlled feasibility trial (SupportBack).

Geraghty AW, Stanford R, Little P, Roberts L, Foster NE, Hill JC, Hay E, Stuart B, Turner D, Yardley L.

BMJ Open. 2015 Sep 23;5(9):e009524. doi: 10.1136/bmjopen-2015-009524.


An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Breen M, Bradley B, Kelly S, Yao G, Raftery J, Mant D, Little P.

Health Technol Assess. 2015 Sep;19(72):1-150. doi: 10.3310/hta19720.


The CHICO (Children's Cough) Trial protocol: a feasibility randomised controlled trial investigating the clinical and cost-effectiveness of a complex intervention to improve the management of children presenting to primary care with acute respiratory tract infection.

Turnbull SL, Redmond NM, Lucas P, Cabral C, Ingram J, Hollinghurst S, Hay AD, Peters TJ, Horwood J, Little P, Francis N, Blair PS.

BMJ Open. 2015 Sep 15;5(9):e008615. doi: 10.1136/bmjopen-2015-008615.


Forkhead box O transcription factors as possible mediators in the development of major depression.

Wang H, Quirion R, Little PJ, Cheng Y, Feng ZP, Sun HS, Xu J, Zheng W.

Neuropharmacology. 2015 Aug 14;99:527-537. doi: 10.1016/j.neuropharm.2015.08.020. [Epub ahead of print] Review.


An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (PRIMIT): a primary care randomised trial.

Little P, Stuart B, Hobbs FD, Moore M, Barnett J, Popoola D, Middleton K, Kelly J, Mullee M, Raftery J, Yao G, Carman W, Fleming D, Stokes-Lampard H, Williamson I, Joseph J, Miller S, Yardley L.

Lancet. 2015 Aug 6. pii: S0140-6736(15)60127-1. doi: 10.1016/S0140-6736(15)60127-1. [Epub ahead of print]


Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P.

CMAJ. 2015 Sep 22;187(13):961-9. doi: 10.1503/cmaj.141608. Epub 2015 Jul 27.


Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised controlled trial of clinical-effectiveness and cost-effectiveness of therapist delivered cognitive behavioural therapy and web-based self-management in irritable bowel syndrome in adults.

Everitt H, Landau S, Little P, Bishop FL, McCrone P, O'Reilly G, Coleman N, Logan R, Chalder T, Moss-Morris R; ACTIB trial team.

BMJ Open. 2015 Jul 15;5(7):e008622. doi: 10.1136/bmjopen-2015-008622.


Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

Wang X, Cheng CY, Liao J, Sim X, Liu J, Chia KS, Tai ES, Little P, Khor CC, Aung T, Wong TY, Teo YY.

Eur J Hum Genet. 2015 Jul 1. doi: 10.1038/ejhg.2015.150. [Epub ahead of print]


Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study.

McLachlan S, Mansell G, Sanders T, Yardley S, van der Windt D, Brindle L, Chew-Graham C, Little P.

Fam Pract. 2015 Oct;32(5):568-77. doi: 10.1093/fampra/cmv048. Epub 2015 Jun 22.


Distinguishing between emotional distress and psychiatric disorder in primary care attenders: A cross sectional study of the four-dimensional symptom questionnaire (4DSQ).

Geraghty AW, Stuart B, Terluin B, Kendrick T, Little P, Moore M.

J Affect Disord. 2015 Sep 15;184:198-204. doi: 10.1016/j.jad.2015.05.064. Epub 2015 Jun 9.


Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care.

van Vugt SF, Broekhuizen BD, Zuithoff NP, van Essen GA, Ebell MH, Coenen S, Ieven M, Lammens C, Goossens H, Butler CC, Hood K, Little P, Verheij TJ; GRACE Consortium.

Fam Pract. 2015 Aug;32(4):408-14. doi: 10.1093/fampra/cmv039. Epub 2015 Jun 4.


Verbal and non-verbal behaviour and patient perception of communication in primary care: an observational study.

Little P, White P, Kelly J, Everitt H, Gashi S, Bikker A, Mercer S.

Br J Gen Pract. 2015 Jun;65(635):e357-65. doi: 10.3399/bjgp15X685249.


Randomised controlled trial of a brief intervention targeting predominantly non-verbal communication in general practice consultations.

Little P, White P, Kelly J, Everitt H, Mercer S.

Br J Gen Pract. 2015 Jun;65(635):e351-6. doi: 10.3399/bjgp15X685237.


Patients' treatment beliefs in low back pain: development and validation of a questionnaire in primary care.

Dima A, Lewith GT, Little P, Moss-Morris R, Foster NE, Hankins M, Surtees G, Bishop FL.

Pain. 2015 Aug;156(8):1489-500. doi: 10.1097/j.pain.0000000000000193.


Can oral corticosteroids reduce the severity or duration of an acute cough, and the associated National Health Service and societal costs, in adults presenting to primary care? Study protocol for a randomised controlled trial.

Downing HE, Carroll F, Brookes ST, Hollinghurst S, Timmins D, Orton E, Wang K, Kendrick D, Little P, Moore MV, Harnden A, Thompson M, May MT, Hay AD; OSAC trial team.

Trials. 2015 Mar 7;16:78. doi: 10.1186/s13063-015-0569-5.


'You don't know which bits to believe': qualitative study exploring carers' experiences of seeking information on the internet about childhood eczema.

Santer M, Muller I, Yardley L, Burgess H, Ersser SJ, Lewis-Jones S, Little P.

BMJ Open. 2015 Apr 8;5(4):e006339. doi: 10.1136/bmjopen-2014-006339.


Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery.

Butler CC, O'Brien K, Pickles T, Hood K, Wootton M, Howe R, Waldron CA, Thomas-Jones E, Hollingworth W, Little P, Van Der Voort J, Dudley J, Rumsby K, Downing H, Harman K, Hay AD; DUTY study team.

Br J Gen Pract. 2015 Apr;65(633):e217-23. doi: 10.3399/bjgp15X684361.


Adherence-adjusted estimates of benefits and harms from treatment with amoxicillin for LRTI: secondary analysis of a 12-country randomised placebo-controlled trial using randomisation-based efficacy estimators.

Gillespie D, Hood K, Farewell D, Butler CC, Verheij T, Goossens H, Stuart B, Mullee M, Little P; GRACE consortium.

BMJ Open. 2015 Mar 6;5(3):e006160. doi: 10.1136/bmjopen-2014-006160.


The added diagnostic value of five different C-reactive protein point-of-care test devices in detecting pneumonia in primary care: A nested case-control study.

Minnaard MC, van de Pol AC, de Groot JA, De Wit NJ, Hopstaken RM, van Delft S, Goossens H, Ieven M, Lammens C, Little P, Butler CC, Broekhuizen BD, Verheij TJ.

Scand J Clin Lab Invest. 2015 Jul;75(4):291-5. doi: 10.3109/00365513.2015.1006136. Epub 2015 Feb 27.

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