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Cost-effectiveness of self-management of blood pressure in hypertensive patients over 70 years with suboptimal control and established cardiovascular disease or additional cardiovascular risk diseases (TASMIN-SR).

Penaloza-Ramos MC, Jowett S, Mant J, Schwartz C, Bray EP, Sayeed Haque M, Richard Hobbs FD, Little P, Bryan S, Williams B, McManus RJ.

Eur J Prev Cardiol. 2015 Nov 24. pii: 2047487315618784. [Epub ahead of print]


Digital Interventions to Promote Self-Management in Adults With Hypertension: Protocol for Systematic Review and Meta-Analysis.

McLean G, Murray E, Band R, Saunderson K, Hanlon P, Little P, McManus RJ, Yardley L, Mair FS.

JMIR Res Protoc. 2015 Nov 20;4(4):e133.


"Lovely Pie in the Sky Plans": A Qualitative Study of Clinicians' Perspectives on Guidelines for Managing Low Back Pain in Primary Care in England.

Bishop FL, Dima AL, Ngui J, Little P, Moss-Morris R, Foster NE, Lewith GT.

Spine (Phila Pa 1976). 2015 Dec;40(23):1842-50. doi: 10.1097/BRS.0000000000001215.


Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes.

Kamato D, Thach L, Getachew R, Burch M, Hollenberg MD, Zheng W, Little PJ, Osman N.

Cell Signal. 2015 Nov 5;28(1):110-119. doi: 10.1016/j.cellsig.2015.11.003. [Epub ahead of print]


Amoxicillin for clinically unsuspected pneumonia in primary care: subgroup analysis.

Teepe J, Little P, Elshof N, Broekhuizen BD, Moore M, Stuart B, Butler CC, Hood K, Ieven M, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Eur Respir J. 2015 Nov 5. pii: ERJ-00611-2015. doi: 10.1183/13993003.00611-2015. [Epub ahead of print] No abstract available.


Bath additives for the treatment of childhood eczema (BATHE): protocol for multicentre parallel group randomised trial.

Santer M, Rumsby K, Ridd MJ, Francis NA, Stuart B, Chorozoglou M, Wood W, Roberts A, Thomas KS, Williams HC, Little P.

BMJ Open. 2015 Nov 1;5(10):e009575. doi: 10.1136/bmjopen-2015-009575.


Views of People With High and Low Levels of Health Literacy About a Digital Intervention to Promote Physical Activity for Diabetes: A Qualitative Study in Five Countries.

Rowsell A, Muller I, Murray E, Little P, Byrne CD, Ganahl K, Müller G, Gibney S, Lyles CR, Lucas A, Nutbeam D, Yardley L.

J Med Internet Res. 2015 Oct 12;17(10):e230. doi: 10.2196/jmir.4999.


Prevalence, diagnosis, and disease course of pertussis in adults with acute cough: a prospective, observational study in primary care.

Teepe J, Broekhuizen BD, Ieven M, Loens K, Huygen K, Kretzschmar M, de Melker H, Butler CC, Little P, Stuart B, Coenen S, Goossens H, Verheij TJ; GRACE consortium.

Br J Gen Pract. 2015 Oct;65(639):e662-7. doi: 10.3399/bjgp15X686917.


Using an internet intervention to support self-management of low back pain in primary care: protocol for a randomised controlled feasibility trial (SupportBack).

Geraghty AW, Stanford R, Little P, Roberts L, Foster NE, Hill JC, Hay E, Stuart B, Turner D, Yardley L.

BMJ Open. 2015 Sep 23;5(9):e009524. doi: 10.1136/bmjopen-2015-009524.


An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Breen M, Bradley B, Kelly S, Yao G, Raftery J, Mant D, Little P.

Health Technol Assess. 2015 Sep;19(72):1-150. doi: 10.3310/hta19720.


The CHICO (Children's Cough) Trial protocol: a feasibility randomised controlled trial investigating the clinical and cost-effectiveness of a complex intervention to improve the management of children presenting to primary care with acute respiratory tract infection.

Turnbull SL, Redmond NM, Lucas P, Cabral C, Ingram J, Hollinghurst S, Hay AD, Peters TJ, Horwood J, Little P, Francis N, Blair PS.

BMJ Open. 2015 Sep 15;5(9):e008615. doi: 10.1136/bmjopen-2015-008615.


Forkhead box O transcription factors as possible mediators in the development of major depression.

Wang H, Quirion R, Little PJ, Cheng Y, Feng ZP, Sun HS, Xu J, Zheng W.

Neuropharmacology. 2015 Dec;99:527-37. doi: 10.1016/j.neuropharm.2015.08.020. Epub 2015 Aug 14. Review.


An internet-delivered handwashing intervention to modify influenza-like illness and respiratory infection transmission (PRIMIT): a primary care randomised trial.

Little P, Stuart B, Hobbs FD, Moore M, Barnett J, Popoola D, Middleton K, Kelly J, Mullee M, Raftery J, Yao G, Carman W, Fleming D, Stokes-Lampard H, Williamson I, Joseph J, Miller S, Yardley L.

Lancet. 2015 Oct 24;386(10004):1631-9. doi: 10.1016/S0140-6736(15)60127-1. Epub 2015 Aug 6.


Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial.

Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P.

CMAJ. 2015 Sep 22;187(13):961-9. doi: 10.1503/cmaj.141608. Epub 2015 Jul 27.


Assessing Cognitive behavioural Therapy in Irritable Bowel (ACTIB): protocol for a randomised controlled trial of clinical-effectiveness and cost-effectiveness of therapist delivered cognitive behavioural therapy and web-based self-management in irritable bowel syndrome in adults.

Everitt H, Landau S, Little P, Bishop FL, McCrone P, O'Reilly G, Coleman N, Logan R, Chalder T, Moss-Morris R; ACTIB trial team.

BMJ Open. 2015 Jul 15;5(7):e008622. doi: 10.1136/bmjopen-2015-008622.


Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

Wang X, Cheng CY, Liao J, Sim X, Liu J, Chia KS, Tai ES, Little P, Khor CC, Aung T, Wong TY, Teo YY.

Eur J Hum Genet. 2015 Jul 1. doi: 10.1038/ejhg.2015.150. [Epub ahead of print]


Symptom perceptions and help-seeking behaviour prior to lung and colorectal cancer diagnoses: a qualitative study.

McLachlan S, Mansell G, Sanders T, Yardley S, van der Windt D, Brindle L, Chew-Graham C, Little P.

Fam Pract. 2015 Oct;32(5):568-77. doi: 10.1093/fampra/cmv048. Epub 2015 Jun 22.


Distinguishing between emotional distress and psychiatric disorder in primary care attenders: A cross sectional study of the four-dimensional symptom questionnaire (4DSQ).

Geraghty AW, Stuart B, Terluin B, Kendrick T, Little P, Moore M.

J Affect Disord. 2015 Sep 15;184:198-204. doi: 10.1016/j.jad.2015.05.064. Epub 2015 Jun 9.


Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care.

van Vugt SF, Broekhuizen BD, Zuithoff NP, van Essen GA, Ebell MH, Coenen S, Ieven M, Lammens C, Goossens H, Butler CC, Hood K, Little P, Verheij TJ; GRACE Consortium.

Fam Pract. 2015 Aug;32(4):408-14. doi: 10.1093/fampra/cmv039. Epub 2015 Jun 4.


Verbal and non-verbal behaviour and patient perception of communication in primary care: an observational study.

Little P, White P, Kelly J, Everitt H, Gashi S, Bikker A, Mercer S.

Br J Gen Pract. 2015 Jun;65(635):e357-65. doi: 10.3399/bjgp15X685249.

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