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Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice.

Jara A, Liu X, Sim D, Benner CM, Duran-Ortiz S, Qian Y, List EO, Berryman DE, Kim JK, Kopchick JJ.

Endocrinology. 2016 May;157(5):1929-41. doi: 10.1210/en.2015-1686. Epub 2016 Apr 1.


Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland.

Liu Y, Knop E, Knop N, Sullivan DA, List EO, Kopchick JJ, Kam WR, Ding J.

J Ophthalmol. 2016;2016:5728071. doi: 10.1155/2016/5728071. Epub 2016 Feb 14.


Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging.

Visser WE, Bombardieri CR, Zevenbergen C, Barnhoorn S, Ottaviani A, van der Pluijm I, Brandt R, Kaptein E, van Heerebeek R, van Toor H, Garinis GA, Peeters RP, Medici M, van Ham W, Vermeij WP, de Waard MC, de Krijger RR, Boelen A, Kwakkel J, Kopchick JJ, List EO, Melis JP, Darras VM, Dollé ME, van der Horst GT, Hoeijmakers JH, Visser TJ.

PLoS One. 2016 Mar 8;11(3):e0149941. doi: 10.1371/journal.pone.0149941. eCollection 2016.


Deconstructing the Growth Hormone Receptor(GHR): Physical and Metabolic Phenotypes of Tissue-Specific GHR Gene-Disrupted Mice.

Young JA, List EO, Kopchick JJ.

Prog Mol Biol Transl Sci. 2016;138:27-39. doi: 10.1016/bs.pmbts.2015.10.014. Epub 2016 Jan 13.


The somatotropic axis and aging: Benefits of endocrine defects.

Bartke A, List EO, Kopchick JJ.

Growth Horm IGF Res. 2016 Apr;27:41-5. doi: 10.1016/j.ghir.2016.02.002. Epub 2016 Feb 16. Review.


Transcriptome profiling reveals divergent expression shifts in brown and white adipose tissue from long-lived GHRKO mice.

Stout MB, Swindell WR, Zhi X, Rohde K, List EO, Berryman DE, Kopchick JJ, Gesing A, Fang Y, Masternak MM.

Oncotarget. 2015 Sep 29;6(29):26702-15. doi: 10.18632/oncotarget.5760.


Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular Senescence.

Comisford R, Lubbers ER, Householder LA, Suer O, Tchkonia T, Kirkland JL, List EO, Kopchick JJ, Berryman DE.

Gerontology. 2016;62(2):163-72. doi: 10.1159/000439050. Epub 2015 Sep 16.


Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice.

Sadagurski M, Landeryou T, Cady G, Kopchick JJ, List EO, Berryman DE, Bartke A, Miller RA.

Aging Cell. 2015 Dec;14(6):1045-54. doi: 10.1111/acel.12382. Epub 2015 Aug 12.


Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice.

List EO, Berryman DE, Ikeno Y, Hubbard GB, Funk K, Comisford R, Young JA, Stout MB, Tchkonia T, Masternak MM, Bartke A, Kirkland JL, Miller RA, Kopchick JJ.

Aging (Albany NY). 2015 Jul;7(7):500-12.


Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice.

Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD.

Diabetes. 2015 Sep;64(9):3093-103. doi: 10.2337/db15-0370. Epub 2015 May 26.


GH action influences adipogenesis of mouse adipose tissue-derived mesenchymal stem cells.

Olarescu NC, Berryman DE, Householder LA, Lubbers ER, List EO, Benencia F, Kopchick JJ, Bollerslev J.

J Endocrinol. 2015 Jul;226(1):13-23. doi: 10.1530/JOE-15-0012. Epub 2015 May 5.


Glucose and Fat Metabolism in Acromegaly: From Mice Models to Patient Care.

Dal J, List EO, Jørgensen JO, Berryman DE.

Neuroendocrinology. 2016;103(1):96-105. doi: 10.1159/000430819. Epub 2015 Apr 29.


Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.

Zawada I, Masternak MM, List EO, Stout MB, Berryman DE, Lewinski A, Kopchick JJ, Bartke A, Karbownik-Lewinska M, Gesing A.

Aging (Albany NY). 2015 Mar;7(3):195-204.

Free PMC Article

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength.

Lim SV, Marenzana M, Hopkinson M, List EO, Kopchick JJ, Pereira M, Javaheri B, Roux JP, Chavassieux P, Korbonits M, Chenu C.

Endocrinology. 2015 Apr;156(4):1362-71. doi: 10.1210/en.2014-1572. Epub 2015 Feb 3.


Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations.

Benencia F, Harshman S, Duran-Ortiz S, Lubbers ER, List EO, Householder L, Al-Naeeli M, Liang X, Welch L, Kopchick JJ, Berryman DE.

Endocrinology. 2015 May;156(5):1794-803. doi: 10.1210/en.2014-1794. Epub 2014 Dec 18.


Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.

Dominick G, Berryman DE, List EO, Kopchick JJ, Li X, Miller RA, Garcia GG.

Endocrinology. 2015 Feb;156(2):565-75. doi: 10.1210/en.2014-1690. Epub 2014 Dec 2.


Growth hormone receptor antagonist transgenic mice are protected from hyperinsulinemia and glucose intolerance despite obesity when placed on a HF diet.

Yang T, Householder LA, Lubbers ER, List EO, Troike K, Vesel C, Duran-Ortiz S, Kopchick JJ, Berryman DE.

Endocrinology. 2015 Feb;156(2):555-64. doi: 10.1210/en.2014-1617. Epub 2014 Nov 18.


The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice.

Baquedano E, Ruiz-Lopez AM, Sustarsic EG, Herpy J, List EO, Chowen JA, Frago LM, Kopchick JJ, Argente J.

Endocrinology. 2014 Dec;155(12):4856-67. doi: 10.1210/en.2014-1367. Epub 2014 Sep 19.


Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

Stout MB, Tchkonia T, Pirtskhalava T, Palmer AK, List EO, Berryman DE, Lubbers ER, Escande C, Spong A, Masternak MM, Oberg AL, LeBrasseur NK, Miller RA, Kopchick JJ, Bartke A, Kirkland JL.

Aging (Albany NY). 2014 Jul;6(7):575-86.


Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent.

Gesing A, Wang F, List EO, Berryman DE, Masternak MM, Lewinski A, Karbownik-Lewinska M, Kopchick JJ, Bartke A.

J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):44-52. doi: 10.1093/gerona/glu008. Epub 2014 Feb 18.

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