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Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.

Nicod J, Davies RW, Cai N, Hassett C, Goodstadt L, Cosgrove C, Yee BK, Lionikaite V, McIntyre RE, Remme CA, Lodder EM, Gregory JS, Hough T, Joynson R, Phelps H, Nell B, Rowe C, Wood J, Walling A, Bopp N, Bhomra A, Hernandez-Pliego P, Callebert J, Aspden RM, Talbot NP, Robbins PA, Harrison M, Fray M, Launay JM, Pinto YM, Blizard DA, Bezzina CR, Adams DJ, Franken P, Weaver T, Wells S, Brown SD, Potter PK, Klenerman P, Lionikas A, Mott R, Flint J.

Nat Genet. 2016 Jul 4. doi: 10.1038/ng.3595. [Epub ahead of print]


Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.

Parker CC, Gopalakrishnan S, Carbonetto P, Gonzales NM, Leung E, Park YJ, Aryee E, Davis J, Blizard DA, Ackert-Bicknell CL, Lionikas A, Pritchard JK, Palmer AA.

Nat Genet. 2016 Jul 4. doi: 10.1038/ng.3609. [Epub ahead of print]


Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.

Joyce PI, Fratta P, Landman AS, Mcgoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, Hilton H, Teboul L, Tucker J, Lionikas A, Estabel J, Ramirez-Solis R, White JK, Brandner S, Plagnol V, Bennet DL, Abramov AY, Greensmith L, Fisher EM, Acevedo-Arozena A.

Hum Mol Genet. 2016 Jan 15;25(2):291-307. doi: 10.1093/hmg/ddv471. Epub 2015 Nov 24.


Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice.

Minderis P, Kilikevicius A, Baltusnikas J, Alhindi Y, Venckunas T, Bunger L, Lionikas A, Ratkevicius A.

Scand J Med Sci Sports. 2016 Aug;26(8):894-901. doi: 10.1111/sms.12532. Epub 2015 Aug 24.


Myostatin dysfunction impairs force generation in extensor digitorum longus muscle and increases exercise-induced protein efflux from extensor digitorum longus and soleus muscles.

Baltusnikas J, Kilikevicius A, Venckunas T, Fokin A, Bünger L, Lionikas A, Ratkevicius A.

Appl Physiol Nutr Metab. 2015 Aug;40(8):817-21. doi: 10.1139/apnm-2014-0513. Epub 2015 Apr 6.


Regenerated soleus muscle shows reduced creatine kinase efflux after contractile activity in vitro.

Baltusnikas J, Kilikevicius A, Venckunas T, Fokin A, Lionikas A, Ratkevicius A.

Appl Physiol Nutr Metab. 2015 Feb;40(2):129-33. doi: 10.1139/apnm-2014-0274. Epub 2014 Oct 15.


Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis.

Corrochano S, Männikkö R, Joyce PI, McGoldrick P, Wettstein J, Lassi G, Raja Rayan DL, Blanco G, Quinn C, Liavas A, Lionikas A, Amior N, Dick J, Healy EG, Stewart M, Carter S, Hutchinson M, Bentley L, Fratta P, Cortese A, Cox R, Brown SD, Tucci V, Wackerhage H, Amato AA, Greensmith L, Koltzenburg M, Hanna MG, Acevedo-Arozena A.

Brain. 2014 Dec;137(Pt 12):3171-85. doi: 10.1093/brain/awu292. Epub 2014 Oct 27.


Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice.

Carbonetto P, Cheng R, Gyekis JP, Parker CC, Blizard DA, Palmer AA, Lionikas A.

Physiol Genomics. 2014 Aug 15;46(16):571-82. doi: 10.1152/physiolgenomics.00055.2014. Epub 2014 Jun 24.


Genetic and genomic analyses of musculoskeletal differences between BEH and BEL strains.

Lionikas A, Kilikevicius A, Bünger L, Meharg C, Carroll AM, Ratkevicius A, Venckunas T, Blizard DA.

Physiol Genomics. 2013 Oct 16;45(20):940-7. doi: 10.1152/physiolgenomics.00109.2013. Epub 2013 Aug 20.


Analyses of muscle spindles in the soleus of six inbred mouse strains.

Lionikas A, Smith CJ, Smith TL, Bünger L, Banks RW, Bewick GS.

J Anat. 2013 Sep;223(3):289-96. doi: 10.1111/joa.12076. Epub 2013 Jul 8.


Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy.

Judson RN, Gray SR, Walker C, Carroll AM, Itzstein C, Lionikas A, Zammit PS, De Bari C, Wackerhage H.

PLoS One. 2013;8(3):e59622. doi: 10.1371/journal.pone.0059622. Epub 2013 Mar 27.


Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses.

Lionikas A, Meharg C, Derry JM, Ratkevicius A, Carroll AM, Vandenbergh DJ, Blizard DA.

BMC Genomics. 2012 Nov 5;13:592. doi: 10.1186/1471-2164-13-592.


Divergent physiological characteristics and responses to endurance training among inbred mouse strains.

Kilikevicius A, Venckunas T, Zelniene R, Carroll AM, Lionikaite S, Ratkevicius A, Lionikas A.

Scand J Med Sci Sports. 2013 Oct;23(5):657-68. doi: 10.1111/j.1600-0838.2012.01451.x. Epub 2012 Mar 13.


QTL Analysis of Type I and Type IIA Fibers in Soleus Muscle in a Cross between LG/J and SM/J Mouse Strains.

Carroll AM, Palmer AA, Lionikas A.

Front Genet. 2012 Jan 6;2:99. doi: 10.3389/fgene.2011.00099. eCollection 2011.


B6-MSM consomic mouse strains reveal multiple loci for genetic variation in sucrose octaacetate aversion.

Ishii A, Koide T, Takahashi A, Shiroishi T, Hettinger TP, Frank ME, Savoy LD, Formaker BK, Yertutanol S, Lionikas A, Blizard DA.

Behav Genet. 2011 Sep;41(5):716-23. doi: 10.1007/s10519-011-9464-3. Epub 2011 Apr 3.


H55N polymorphism as a likely cause of variation in citrate synthase activity of mouse skeletal muscle.

Ratkevicius A, Carroll AM, Kilikevicius A, Venckunas T, McDermott KT, Gray SR, Wackerhage H, Lionikas A.

Physiol Genomics. 2010 Oct;42A(2):96-102. doi: 10.1152/physiolgenomics.00066.2010. Epub 2010 Aug 17.


Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses.

Lionikas A, Cheng R, Lim JE, Palmer AA, Blizard DA.

Physiol Genomics. 2010 Sep;42A(1):33-8. doi: 10.1152/physiolgenomics.00100.2010. Epub 2010 Jul 13.


Genomic analysis of variation in hindlimb musculature of mice from the C57BL/6J and DBA/2J lineage.

Lionikas A, Carlborg O, Lu L, Peirce JL, Williams RW, Yu F, Vogler GP, McClearn GE, Blizard DA.

J Hered. 2010 May-Jun;101(3):360-7. doi: 10.1093/jhered/esq023. Epub 2010 Mar 16.


Genetic architecture for hole-board behaviors across substantial time intervals in young, middle-aged and old mice.

Foreman JE, Lionikas A, Lang DH, Gyekis JP, Krishnan M, Sharkey NA, Gerhard GS, Grant MD, Vogler GP, Mack HA, Stout JT, Griffith JW, Lakoski JM, Hofer SM, McClearn GE, Vandenbergh DJ, Blizard DA.

Genes Brain Behav. 2009 Oct;8(7):714-27. doi: 10.1111/j.1601-183X.2009.00516.x. Epub 2009 Jun 23.


QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains.

Umemori J, Nishi A, Lionikas A, Sakaguchi T, Kuriki S, Blizard DA, Koide T.

BMC Genet. 2009 Jul 29;10:40. doi: 10.1186/1471-2156-10-40.

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