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Results: 1 to 20 of 129

1.

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

Tonomura N, Elvers I, Thomas R, Megquier K, Turner-Maier J, Howald C, Sarver AL, Swofford R, Frantz AM, Ito D, Mauceli E, Arendt M, Noh HJ, Koltookian M, Biagi T, Fryc S, Williams C, Avery AC, Kim JH, Barber L, Burgess K, Lander ES, Karlsson EK, Azuma C, Modiano JF, Breen M, Lindblad-Toh K.

PLoS Genet. 2015 Feb 2;11(2):e1004922. doi: 10.1371/journal.pgen.1004922. eCollection 2015 Feb.

2.

Convergent evolution of the genomes of marine mammals.

Foote AD, Liu Y, Thomas GW, Vinař T, Alföldi J, Deng J, Dugan S, van Elk CE, Hunter ME, Joshi V, Khan Z, Kovar C, Lee SL, Lindblad-Toh K, Mancia A, Nielsen R, Qin X, Qu J, Raney BJ, Vijay N, Wolf JB, Hahn MW, Muzny DM, Worley KC, Gilbert MT, Gibbs RA.

Nat Genet. 2015 Mar;47(3):272-5. doi: 10.1038/ng.3198. Epub 2015 Jan 26.

PMID:
25621460
3.

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.

Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, Berlin AM, Lara M, Russell P, Swofford R, Turner-Maier J, Young S, Hourlier T, Aken B, Searle S, Sun X, Yi Y, Suresh M, Tumpey TM, Siepel A, Wisely SM, Dessimoz C, Kawaoka Y, Birren BW, Lindblad-Toh K, Di Palma F, Engelhardt JF, Palermo RE, Katze MG.

Nat Biotechnol. 2014 Dec;32(12):1250-5. doi: 10.1038/nbt.3079. Epub 2014 Nov 17.

4.

The genomic substrate for adaptive radiation in African cichlid fish.

Brawand D, Wagner CE, Li YI, Malinsky M, Keller I, Fan S, Simakov O, Ng AY, Lim ZW, Bezault E, Turner-Maier J, Johnson J, Alcazar R, Noh HJ, Russell P, Aken B, Alföldi J, Amemiya C, Azzouzi N, Baroiller JF, Barloy-Hubler F, Berlin A, Bloomquist R, Carleton KL, Conte MA, D'Cotta H, Eshel O, Gaffney L, Galibert F, Gante HF, Gnerre S, Greuter L, Guyon R, Haddad NS, Haerty W, Harris RM, Hofmann HA, Hourlier T, Hulata G, Jaffe DB, Lara M, Lee AP, MacCallum I, Mwaiko S, Nikaido M, Nishihara H, Ozouf-Costaz C, Penman DJ, Przybylski D, Rakotomanga M, Renn SC, Ribeiro FJ, Ron M, Salzburger W, Sanchez-Pulido L, Santos ME, Searle S, Sharpe T, Swofford R, Tan FJ, Williams L, Young S, Yin S, Okada N, Kocher TD, Miska EA, Lander ES, Venkatesh B, Fernald RD, Meyer A, Ponting CP, Streelman JT, Lindblad-Toh K, Seehausen O, Di Palma F.

Nature. 2014 Sep 18;513(7518):375-81. doi: 10.1038/nature13726. Epub 2014 Sep 3.

5.

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.

Keane M, Craig T, Alföldi J, Berlin AM, Johnson J, Seluanov A, Gorbunova V, Di Palma F, Lindblad-Toh K, Church GM, de Magalhães JP.

Bioinformatics. 2014 Dec 15;30(24):3558-60. doi: 10.1093/bioinformatics/btu579. Epub 2014 Aug 28.

6.

Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication.

Carneiro M, Rubin CJ, Di Palma F, Albert FW, Alföldi J, Barrio AM, Pielberg G, Rafati N, Sayyab S, Turner-Maier J, Younis S, Afonso S, Aken B, Alves JM, Barrell D, Bolet G, Boucher S, Burbano HA, Campos R, Chang JL, Duranthon V, Fontanesi L, Garreau H, Heiman D, Johnson J, Mage RG, Peng Z, Queney G, Rogel-Gaillard C, Ruffier M, Searle S, Villafuerte R, Xiong A, Young S, Forsberg-Nilsson K, Good JM, Lander ES, Ferrand N, Lindblad-Toh K, Andersson L.

Science. 2014 Aug 29;345(6200):1074-9. doi: 10.1126/science.1253714.

PMID:
25170157
7.

Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.

Ahlgren KM, Fall T, Landegren N, Grimelius L, von Euler H, Sundberg K, Lindblad-Toh K, Lobell A, Hedhammar Å, Andersson G, Hansson-Hamlin H, Lernmark Å, Kämpe O.

PLoS One. 2014 Aug 25;9(8):e105473. doi: 10.1371/journal.pone.0105473. eCollection 2014.

8.

A simple repeat polymorphism in the MITF-M promoter is a key regulator of white spotting in dogs.

Baranowska Körberg I, Sundström E, Meadows JR, Rosengren Pielberg G, Gustafson U, Hedhammar Å, Karlsson EK, Seddon J, Söderberg A, Vilà C, Zhang X, Åkesson M, Lindblad-Toh K, Andersson G, Andersson L.

PLoS One. 2014 Aug 12;9(8):e104363. doi: 10.1371/journal.pone.0104363. eCollection 2014.

9.

Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder.

Tang R, Noh HJ, Wang D, Sigurdsson S, Swofford R, Perloski M, Duxbury M, Patterson EE, Albright J, Castelhano M, Auton A, Boyko AR, Feng G, Lindblad-Toh K, Karlsson EK.

Genome Biol. 2014 Mar 14;15(3):R25. doi: 10.1186/gb-2014-15-3-r25.

10.

Amylase activity is associated with AMY2B copy numbers in dog: implications for dog domestication, diet and diabetes.

Arendt M, Fall T, Lindblad-Toh K, Axelsson E.

Anim Genet. 2014 Oct;45(5):716-22. doi: 10.1111/age.12179. Epub 2014 Jun 28.

11.

The dog as a genetic model for immunoglobulin A (IgA) deficiency: identification of several breeds with low serum IgA concentrations.

Olsson M, Frankowiack M, Tengvall K, Roosje P, Fall T, Ivansson E, Bergvall K, Hansson-Hamlin H, Sundberg K, Hedhammar A, Lindblad-Toh K, Hammarström L.

Vet Immunol Immunopathol. 2014 Aug 15;160(3-4):255-9. doi: 10.1016/j.vetimm.2014.05.010. Epub 2014 May 27.

PMID:
24935667
12.

Genome-wide copy number variant discovery in dogs using the CanineHD genotyping array.

Molin AM, Berglund J, Webster MT, Lindblad-Toh K.

BMC Genomics. 2014 Mar 19;15:210. doi: 10.1186/1471-2164-15-210.

13.

An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.

Hoeppner MP, Lundquist A, Pirun M, Meadows JR, Zamani N, Johnson J, Sundström G, Cook A, FitzGerald MG, Swofford R, Mauceli E, Moghadam BT, Greka A, Alföldi J, Abouelleil A, Aftuck L, Bessette D, Berlin A, Brown A, Gearin G, Lui A, Macdonald JP, Priest M, Shea T, Turner-Maier J, Zimmer A, Lander ES, di Palma F, Lindblad-Toh K, Grabherr MG.

PLoS One. 2014 Mar 13;9(3):e91172. doi: 10.1371/journal.pone.0091172. eCollection 2014.

14.

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma.

Thomas R, Borst L, Rotroff D, Motsinger-Reif A, Lindblad-Toh K, Modiano JF, Breen M.

Chromosome Res. 2014 Sep;22(3):305-19. doi: 10.1007/s10577-014-9406-z. Epub 2014 Mar 6.

PMID:
24599718
15.

Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.

Gorden BH, Kim JH, Sarver AL, Frantz AM, Breen M, Lindblad-Toh K, O'Brien TD, Sharkey LC, Modiano JF, Dickerson EB.

Am J Pathol. 2014 Apr;184(4):985-95. doi: 10.1016/j.ajpath.2013.12.025. Epub 2014 Feb 11.

16.

Breed distribution of SOD1 alleles previously associated with canine degenerative myelopathy.

Zeng R, Coates JR, Johnson GC, Hansen L, Awano T, Kolicheski A, Ivansson E, Perloski M, Lindblad-Toh K, O'Brien DP, Guo J, Katz ML, Johnson GS.

J Vet Intern Med. 2014 Mar-Apr;28(2):515-21. doi: 10.1111/jvim.12317. Epub 2014 Feb 13.

17.

Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24.

Agler C, Nielsen DM, Urkasemsin G, Singleton A, Tonomura N, Sigurdsson S, Tang R, Linder K, Arepalli S, Hernandez D, Lindblad-Toh K, van de Leemput J, Motsinger-Reif A, O'Brien DP, Bell J, Harris T, Steinberg S, Olby NJ.

PLoS Genet. 2014 Feb 6;10(2):e1003991. doi: 10.1371/journal.pgen.1003991. eCollection 2014 Feb.

18.

Breed differences in natriuretic peptides in healthy dogs.

Sjöstrand K, Wess G, Ljungvall I, Häggström J, Merveille AC, Wiberg M, Gouni V, Lundgren Willesen J, Hanås S, Lequarré AS, Mejer Sørensen L, Wolf J, Tiret L, Kierczak M, Forsberg S, McEntee K, Battaille G, Seppälä E, Lindblad-Toh K, Georges M, Lohi H, Chetboul V, Fredholm M, Höglund K.

J Vet Intern Med. 2014 Mar-Apr;28(2):451-7. doi: 10.1111/jvim.12310. Epub 2014 Feb 3.

PMID:
24495256
19.

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.

Karlsson EK, Sigurdsson S, Ivansson E, Thomas R, Elvers I, Wright J, Howald C, Tonomura N, Perloski M, Swofford R, Biagi T, Fryc S, Anderson N, Courtay-Cahen C, Youell L, Ricketts SL, Mandlebaum S, Rivera P, von Euler H, Kisseberth WC, London CA, Lander ES, Couto G, Comstock K, Starkey MP, Modiano JF, Breen M, Lindblad-Toh K.

Genome Biol. 2013 Dec 12;14(12):R132. doi: 10.1186/gb-2013-14-12-r132.

20.

Thorough investigation of a canine autoinflammatory disease (AID) confirms one main risk locus and suggests a modifier locus for amyloidosis.

Olsson M, Tintle L, Kierczak M, Perloski M, Tonomura N, Lundquist A, Murén E, Fels M, Tengvall K, Pielberg G, Dufaure de Citres C, Dorso L, Abadie J, Hanson J, Thomas A, Leegwater P, Hedhammar Å, Lindblad-Toh K, Meadows JR.

PLoS One. 2013 Oct 9;8(10):e75242. doi: 10.1371/journal.pone.0075242. eCollection 2013.

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