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Items: 1 to 20 of 27


Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway.

Hsu MC, Hung WC, Yamaguchi H, Lim SO, Liao HW, Tsai CH, Hung MC.

Am J Cancer Res. 2016 Feb 15;6(3):628-38. eCollection 2016.


EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape.

Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D, Djukovic D, Gu H, Chang WC, Wang HL, Chen ML, Huo L, Chen CH, Wu Y, Sahin A, Hanash SM, Hortobagyi GN, Hung MC.

Cancer Res. 2016 Mar 1;76(5):1284-96. doi: 10.1158/0008-5472.CAN-15-2478. Epub 2016 Jan 12.


AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.

Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC.

Cancer Res. 2016 Mar 15;76(6):1451-62. doi: 10.1158/0008-5472.CAN-15-1941. Epub 2016 Jan 12.


Low pepsinogen I level predicts multiple gastric epithelial neoplasias for endoscopic resection.

Park SY, Lim SO, Ki HS, Jun CH, Park CH, Kim HS, Choi SK, Rew JS.

Gut Liver. 2014 May;8(3):277-81. doi: 10.5009/gnl.2014.8.3.277.


EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

Shen J, Xia W, Khotskaya YB, Huo L, Nakanishi K, Lim SO, Du Y, Wang Y, Chang WC, Chen CH, Hsu JL, Wu Y, Lam YC, James BP, Liu X, Liu CG, Patel DJ, Hung MC.

Nature. 2013 May 16;497(7449):383-7. doi: 10.1038/nature12080. Epub 2013 May 1.


Snail inhibits Notch1 intracellular domain mediated transcriptional activation via competing with MAML1.

Kim HS, Jeong H, Lim SO, Jung G.

Biochem Biophys Res Commun. 2013 Mar 29;433(1):6-10. doi: 10.1016/j.bbrc.2013.02.079. Epub 2013 Feb 27.


Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1.

Li CW, Xia W, Huo L, Lim SO, Wu Y, Hsu JL, Chao CH, Yamaguchi H, Yang NK, Ding Q, Wang Y, Lai YJ, LaBaff AM, Wu TJ, Lin BR, Yang MH, Hortobagyi GN, Hung MC.

Cancer Res. 2012 Mar 1;72(5):1290-300. doi: 10.1158/0008-5472.CAN-11-3123. Epub 2012 Jan 17.


Notch1 binds and induces degradation of Snail in hepatocellular carcinoma.

Lim SO, Kim HS, Quan X, Ahn SM, Kim H, Hsieh D, Seong JK, Jung G.

BMC Biol. 2011 Nov 30;9:83. doi: 10.1186/1741-7007-9-83.


Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.

Quan X, Lim SO, Jung G.

FEBS Lett. 2011 Nov 4;585(21):3436-41. doi: 10.1016/j.febslet.2011.09.035. Epub 2011 Oct 6.


Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma.

Lim SO, Park YM, Kim HS, Quan X, Yoo JE, Park YN, Choi GH, Jung G.

Hepatology. 2011 Apr;53(4):1352-62. doi: 10.1002/hep.24208.


Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors.

Song H, Li CW, Labaff AM, Lim SO, Li LY, Kan SF, Chen Y, Zhang K, Lang J, Xie X, Wang Y, Huo LF, Hsu SC, Chen X, Zhao Y, Hung MC.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):68-73. doi: 10.1016/j.bbrc.2010.11.064. Epub 2010 Nov 19.


Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt/β-catenin signaling.

Hsieh A, Kim HS, Lim SO, Yu DY, Jung G.

Cancer Lett. 2011 Jan 28;300(2):162-72. doi: 10.1016/j.canlet.2010.09.018. Epub 2010 Oct 23.


Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter.

Min JY, Lim SO, Jung G.

FEBS Lett. 2010 Jun 3;584(11):2427-32. doi: 10.1016/j.febslet.2010.04.048. Epub 2010 Apr 21.


p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma.

Lim SO, Kim H, Jung G.

FEBS Lett. 2010 Jun 3;584(11):2231-6. doi: 10.1016/j.febslet.2010.04.006. Epub 2010 Apr 10.


Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter.

Lim SO, Gu JM, Kim MS, Kim HS, Park YN, Park CK, Cho JW, Park YM, Jung G.

Gastroenterology. 2008 Dec;135(6):2128-40, 2140.e1-8. doi: 10.1053/j.gastro.2008.07.027. Epub 2008 Jul 31.


Requirement of the cyclic adenosine monophosphate response element-binding protein for hepatitis B virus replication.

Kim BK, Lim SO, Park YG.

Hepatology. 2008 Aug;48(2):361-73. doi: 10.1002/hep.22359.


A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion.

Gu JM, Lim SO, Park YM, Jung G.

FEBS J. 2008 Jun;275(12):3145-56. doi: 10.1111/j.1742-4658.2008.06467.x. Epub 2008 May 16.


HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species.

Gu JM, Lim SO, Oh SJ, Yoon SM, Seong JK, Jung G.

Virus Res. 2008 May;133(2):167-77. doi: 10.1016/j.virusres.2007.12.014. Epub 2008 Feb 8.


Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface.

Lee HH, Kim HS, Kang JY, Lee BI, Ha JY, Yoon HJ, Lim SO, Jung G, Suh SW.

Proteins. 2007 Nov 15;69(3):672-8. No abstract available.


The hepatitis B virus X protein up-regulates lymphotoxin alpha expression in hepatocytes.

Lee SH, Park SG, Lim SO, Jung G.

Biochim Biophys Acta. 2005 Jun 30;1741(1-2):75-84. Epub 2004 Oct 28.

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