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Items: 1 to 20 of 133

1.

Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.

Kumar G, Patlolla JM, Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Singh A, Gillaspy A, Lightfoot S, Steele VE, Kopelovich L, Rao CV.

Am J Cancer Res. 2016 May 1;6(5):894-909. eCollection 2016.

2.

The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice.

Campbell SC, Wisniewski PJ, Noji M, McGuinness LR, Häggblom MM, Lightfoot SA, Joseph LB, Kerkhof LJ.

PLoS One. 2016 Mar 8;11(3):e0150502. doi: 10.1371/journal.pone.0150502. eCollection 2016.

3.

Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer.

Rao CV, Janakiram NB, Madka V, Kumar G, Scott EJ, Pathuri G, Bryant T, Kutche H, Zhang Y, Biddick L, Gali H, Zhao YD, Lightfoot S, Mohammed A.

Cancer Res. 2016 Apr 1;76(7):1965-74. doi: 10.1158/0008-5472.CAN-15-2820. Epub 2016 Feb 15.

PMID:
26880801
4.

Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice.

Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Janakiram NB, Mohammed A, Dai W, Yamada HY.

Cancer Res. 2016 Feb 1;76(3):630-42. doi: 10.1158/0008-5472.CAN-15-0940.

PMID:
26833665
5.

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.

Kim TD, Jin F, Shin S, Oh S, Lightfoot SA, Grande JP, Johnson AJ, van Deursen JM, Wren JD, Janknecht R.

J Clin Invest. 2016 Feb;126(2):706-20. doi: 10.1172/JCI78132. Epub 2016 Jan 5.

6.

TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma.

Madka V, Mohammed A, Li Q, Zhang Y, Kumar G, Lightfoot S, Wu X, Steele V, Kopelovich L, Rao CV.

Am J Cancer Res. 2015 Sep 15;5(10):3030-41. eCollection 2015.

7.

Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo.

Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Patlolla JM, Lightfoot S, Towner RA, Wu XR, Steele VE, Kopelovich L, Rao CV.

Cancer Prev Res (Phila). 2016 Jan;9(1):53-62. doi: 10.1158/1940-6207.CAPR-15-0199. Epub 2015 Nov 17.

PMID:
26577454
8.

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.

Sureban SM, Madhoun MF, May R, Qu D, Ali N, Fazili J, Weygant N, Chandrakesan P, Ding K, Lightfoot SA, Houchen CW.

Oncotarget. 2015 Nov 10;6(35):37200-15. doi: 10.18632/oncotarget.5808.

9.

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma.

Rao CV, Janakiram NB, Madka V, Devarkonda V, Brewer M, Biddick L, Lightfoot S, Steele VE, Mohammed A.

Oncotarget. 2015 Oct 20;6(32):33290-305. doi: 10.18632/oncotarget.5396.

10.

Early and delayed intervention with rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice.

Patlolla JM, Kopelovich L, Qian L, Zhang Y, Kumar G, Madka V, Mohammed A, Biddick L, Sadeghi M, Lightfoot S, Rao CV.

Oncol Rep. 2015 Dec;34(6):2925-34. doi: 10.3892/or.2015.4277. Epub 2015 Sep 16.

PMID:
26397133
11.

Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury.

Sureban SM, May R, Qu D, Chandrakesan P, Weygant N, Ali N, Lightfoot SA, Ding K, Umar S, Schlosser MJ, Houchen CW.

PLoS One. 2015 Aug 13;10(8):e0135561. doi: 10.1371/journal.pone.0135561. eCollection 2015.

12.

A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes.

Rendina-Ruedy E, Hembree KD, Sasaki A, Davis MR, Lightfoot SA, Clarke SL, Lucas EA, Smith BJ.

J Nutr Metab. 2015;2015:758080. doi: 10.1155/2015/758080. Epub 2015 Jun 3.

13.

Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.

Mohammed A, Janakiram NB, Madka V, Brewer M, Ritchie RL, Lightfoot S, Kumar G, Sadeghi M, Patlolla JM, Yamada HY, Cruz-Monserrate Z, May R, Houchen CW, Steele VE, Rao CV.

Oncotarget. 2015 Jun 20;6(17):15524-39.

14.

Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model.

Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Dai W, Yamada HY.

Mol Carcinog. 2016 May;55(5):600-10. doi: 10.1002/mc.22306. Epub 2015 Mar 14.

PMID:
25773652
15.

Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice.

Yamada HY, Zhang Y, Reddy A, Mohammed A, Lightfoot S, Dai W, Rao CV.

Carcinogenesis. 2015 Apr;36(4):429-40. doi: 10.1093/carcin/bgv011. Epub 2015 Mar 4.

16.

Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells.

Qu D, Johnson J, Chandrakesan P, Weygant N, May R, Aiello N, Rhim A, Zhao L, Zheng W, Lightfoot S, Pant S, Irvan J, Postier R, Hocker J, Hanas JS, Ali N, Sureban SM, An G, Schlosser MJ, Stanger B, Houchen CW.

PLoS One. 2015 Feb 27;10(2):e0118933. doi: 10.1371/journal.pone.0118933. eCollection 2015.

17.

Improved innate immune responses by Frondanol A5, a sea cucumber extract, prevent intestinal tumorigenesis.

Janakiram NB, Mohammed A, Bryant T, Lightfoot S, Collin PD, Steele VE, Rao CV.

Cancer Prev Res (Phila). 2015 Apr;8(4):327-37. doi: 10.1158/1940-6207.CAPR-14-0380. Epub 2015 Feb 5.

18.

Discriminating patients with early-stage pancreatic cancer or chronic pancreatitis using serum electrospray mass profiling.

Hocker JR, Postier RG, Li M, Lerner MR, Lightfoot SA, Peyton MD, Deb SJ, Baker CM, Williams TL, Hanas RJ, Stowell DE, Lander TJ, Brackett DJ, Hanas JS.

Cancer Lett. 2015 Apr 10;359(2):314-24. doi: 10.1016/j.canlet.2015.01.035. Epub 2015 Jan 28.

19.

Designing safety policies to meet evolving needs: iGEM as a testbed for proactive and adaptive risk management.

McNamara J, Lightfoot SB, Drinkwater K, Appleton E, Oye K.

ACS Synth Biol. 2014 Dec 19;3(12):983-5. doi: 10.1021/sb500058e.

PMID:
25524105
20.

DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma.

Whorton J, Sureban SM, May R, Qu D, Lightfoot SA, Madhoun M, Johnson M, Tierney WM, Maple JT, Vega KJ, Houchen CW.

Dig Dis Sci. 2015 Feb;60(2):509-13. doi: 10.1007/s10620-014-3347-4. Epub 2014 Oct 5.

PMID:
25283374
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