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Results: 1 to 20 of 253

1.

Full FAAH inhibition combined with partial monoacylglycerol lipase inhibition: Augmented and sustained antinociceptive effects with negligible cannabimimetic side effects in mice.

Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdulla RA, Selley DE, Sim-Selley L, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2015 May 21. pii: jpet.115.222851. [Epub ahead of print]

2.

Dendritic Cells in Kidney Transplant Biopsy Samples Are Associated with T Cell Infiltration and Poor Allograft Survival.

Batal I, De Serres SA, Safa K, Bijol V, Ueno T, Onozato ML, Iafrate AJ, Herter JM, Lichtman AH, Mayadas TN, Guleria I, Rennke HG, Najafian N, Chandraker A.

J Am Soc Nephrol. 2015 Apr 8. pii: ASN.2014080804. [Epub ahead of print]

PMID:
25855773
3.

Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice.

Grim TW, Wiebelhaus JM, Morales AJ, Negus SS, Lichtman AH.

Drug Alcohol Depend. 2015 May 1;150:31-7. doi: 10.1016/j.drugalcdep.2015.01.022. Epub 2015 Jan 29.

PMID:
25772438
4.

Selective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in mice.

Ignatowska-Jankowska B, Wilkerson JL, Mustafa M, Abdullah R, Niphakis M, Wiley JL, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2015 May;353(2):424-32. doi: 10.1124/jpet.114.222315. Epub 2015 Mar 11.

PMID:
25762694
5.

HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction.

Poklis JL, Clay DJ, Ignatowska-Jankowska BM, Zanato C, Ross RA, Greig IR, Abdullah RA, Mustafa MA, Lichtman AH, Poklis A.

J Anal Toxicol. 2015 Jun;39(5):353-8. doi: 10.1093/jat/bkv015. Epub 2015 Mar 3.

PMID:
25737338
6.

Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge.

Nass SR, Long JZ, Schlosburg JE, Cravatt BF, Lichtman AH, Kinsey SG.

J Neuroimmune Pharmacol. 2015 Feb 27. [Epub ahead of print]

PMID:
25715681
7.

Simultaneous inhibition of fatty acid amide hydrolase and monoacylglycerol lipase shares discriminative stimulus effects with Δ9-tetrahydrocannabinol in mice.

Hruba L, Seillier A, Zaki A, Cravatt BF, Lichtman AH, Giuffrida A, McMahon LR.

J Pharmacol Exp Ther. 2015 May;353(2):261-8. doi: 10.1124/jpet.115.222836. Epub 2015 Feb 24.

PMID:
25711338
8.

IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis.

Watkins AA, Yasuda K, Wilson GE, Aprahamian T, Xie Y, Maganto-Garcia E, Shukla P, Oberlander L, Laskow B, Menn-Josephy H, Wu Y, Duffau P, Fried SK, Lichtman AH, Bonegio RG, Rifkin IR.

J Immunol. 2015 Feb 15;194(4):1467-79. doi: 10.4049/jimmunol.1402807. Epub 2015 Jan 16.

PMID:
25595782
9.

Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice.

Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH.

Drug Alcohol Depend. 2015 Jan 1;146:7-16. doi: 10.1016/j.drugalcdep.2014.11.015. Epub 2014 Nov 26.

PMID:
25479915
10.

Treating atherosclerosis with regulatory T cells.

Foks AC, Lichtman AH, Kuiper J.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):280-7. doi: 10.1161/ATVBAHA.114.303568. Epub 2014 Nov 20. Review.

PMID:
25414253
11.

Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice.

Wiebelhaus JM, Grim TW, Owens RA, Lazenka MF, Sim-Selley LJ, Abdullah RA, Niphakis MJ, Vann RE, Cravatt BF, Wiley JL, Negus SS, Lichtman AH.

J Pharmacol Exp Ther. 2015 Feb;352(2):195-207. doi: 10.1124/jpet.114.218677. Epub 2014 Nov 14.

PMID:
25398241
12.

NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.

Brown JD, Lin CY, Duan Q, Griffin G, Federation AJ, Paranal RM, Bair S, Newton G, Lichtman AH, Kung AL, Yang T, Wang H, Luscinskas FW, Croce KJ, Bradner JE, Plutzky J.

Mol Cell. 2014 Oct 23;56(2):219-31. doi: 10.1016/j.molcel.2014.08.024. Epub 2014 Sep 25.

PMID:
25263595
13.

Inhibition of monoacylglycerol lipase reduces nicotine withdrawal.

Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI.

Br J Pharmacol. 2015 Feb;172(3):869-82. doi: 10.1111/bph.12948.

PMID:
25258021
14.

Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters.

Sexton M, Cudaback E, Abdullah RA, Finnell J, Mischley LK, Rozga M, Lichtman AH, Stella N.

Inflammopharmacology. 2014 Oct;22(5):295-303. doi: 10.1007/s10787-014-0214-z. Epub 2014 Aug 19.

PMID:
25135301
15.

Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions.

Lazenka MF, David BG, Lichtman AH, Nestler EJ, Selley DE, Sim-Selley LJ.

Biochem Pharmacol. 2014 Oct 1;91(3):380-9. doi: 10.1016/j.bcp.2014.07.024. Epub 2014 Aug 2.

PMID:
25093286
16.

Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus.

Parker LA, Niphakis MJ, Downey R, Limebeer CL, Rock EM, Sticht MA, Morris H, Abdullah RA, Lichtman AH, Cravatt BF.

Psychopharmacology (Berl). 2015 Feb;232(3):583-93. doi: 10.1007/s00213-014-3696-x. Epub 2014 Aug 3.

PMID:
25085768
17.

Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models.

Grim TW, Ghosh S, Hsu KL, Cravatt BF, Kinsey SG, Lichtman AH.

Pharmacol Biochem Behav. 2014 Sep;124:405-11. doi: 10.1016/j.pbb.2014.07.008. Epub 2014 Jul 21.

PMID:
25058512
18.

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory.

Hait NC, Wise LE, Allegood JC, O'Brien M, Avni D, Reeves TM, Knapp PE, Lu J, Luo C, Miles MF, Milstien S, Lichtman AH, Spiegel S.

Nat Neurosci. 2014 Jul;17(7):971-80. doi: 10.1038/nn.3728. Epub 2014 May 25.

19.

Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents.

Wiley JL, Walentiny DM, Wright MJ Jr, Beardsley PM, Burston JJ, Poklis JL, Lichtman AH, Vann RE.

Eur J Pharmacol. 2014 Aug 15;737:97-105. doi: 10.1016/j.ejphar.2014.05.013. Epub 2014 May 22.

PMID:
24858366
20.

Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice.

Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2014 Aug;350(2):196-204. doi: 10.1124/jpet.114.212753. Epub 2014 May 21.

PMID:
24849924
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