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Results: 1 to 20 of 77

1.

DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation.

Soto I, Howell GR, John CW, Kief JL, Libby RT, John SW.

PLoS One. 2014 Sep 10;9(9):e107291. doi: 10.1371/journal.pone.0107291. eCollection 2014.

PMID:
25207540
[PubMed - in process]
Free PMC Article
2.

DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.

Fernandes KA, Harder JM, John SW, Shrager P, Libby RT.

Neurobiol Dis. 2014 Sep;69:108-16. doi: 10.1016/j.nbd.2014.05.015. Epub 2014 May 27.

PMID:
24878510
[PubMed - in process]
3.

Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival.

Coleman JA, Zhu X, Djajadi HR, Molday LL, Smith RS, Libby RT, John SW, Molday RS.

J Cell Sci. 2014 Mar 1;127(Pt 5):1138-49. doi: 10.1242/jcs.145052. Epub 2014 Jan 10.

PMID:
24413176
[PubMed - in process]
Free PMC Article
4.

Focal damage to macaque photoreceptors produces persistent visual loss.

Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, DiLoreto DA Jr, Libby RT, Williams DR, Merigan WH.

Exp Eye Res. 2014 Feb;119:88-96. doi: 10.1016/j.exer.2013.11.001. Epub 2013 Dec 5.

PMID:
24316158
[PubMed - indexed for MEDLINE]
5.

Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.

Mason AG, Tomé S, Simard JP, Libby RT, Bammler TK, Beyer RP, Morton AJ, Pearson CE, La Spada AR.

Hum Mol Genet. 2014 Mar 15;23(6):1606-18. doi: 10.1093/hmg/ddt551. Epub 2013 Nov 3.

PMID:
24191263
[PubMed - in process]
6.

Adding metabolomics to the toolbox for studying retinal disease.

Howell GR, Libby RT.

Invest Ophthalmol Vis Sci. 2013 Jun 21;54(6):4260. doi: 10.1167/iovs.13-12479. No abstract available.

PMID:
23794537
[PubMed - indexed for MEDLINE]
Free Article
7.

Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.

Zhou Y, Tanzie C, Yan Z, Chen S, Duncan M, Gaudenz K, Li H, Seidel C, Lewis B, Moran A, Libby RT, Kiernan AE, Xie T.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8966-71. doi: 10.1073/pnas.1218145110. Epub 2013 May 15.

PMID:
23676271
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.

Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L.

J Biol Chem. 2013 Jun 21;288(25):18429-38. doi: 10.1074/jbc.M113.478503. Epub 2013 May 6.

PMID:
23649630
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells.

Fernandes KA, Harder JM, Kim J, Libby RT.

Exp Eye Res. 2013 Jul;112:106-17. doi: 10.1016/j.exer.2013.04.021. Epub 2013 May 3.

PMID:
23648575
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Lack of C9ORF72 coding mutations supports a gain of function for repeat expansions in amyotrophic lateral sclerosis.

Harms MB, Cady J, Zaidman C, Cooper P, Bali T, Allred P, Cruchaga C, Baughn M, Libby RT, Pestronk A, Goate A, Ravits J, Baloh RH.

Neurobiol Aging. 2013 Sep;34(9):2234.e13-9. doi: 10.1016/j.neurobiolaging.2013.03.006. Epub 2013 Apr 16.

PMID:
23597494
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death.

Harder JM, Libby RT.

Cell Death Differ. 2013 Jan;20(1):182. doi: 10.1038/cdd.2012.119. Epub 2012 Sep 21. No abstract available.

PMID:
22996683
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutations in a P-type ATPase gene cause axonal degeneration.

Zhu X, Libby RT, de Vries WN, Smith RS, Wright DL, Bronson RT, Seburn KL, John SW.

PLoS Genet. 2012;8(8):e1002853. doi: 10.1371/journal.pgen.1002853. Epub 2012 Aug 9.

PMID:
22912588
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells.

Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT.

Mol Cell Neurosci. 2012 Aug;51(1-2):53-9. doi: 10.1016/j.mcn.2012.07.006. Epub 2012 Jul 24.

PMID:
22836101
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice.

Harder JM, Fernandes KA, Libby RT.

Sci Rep. 2012;2:530. doi: 10.1038/srep00530. Epub 2012 Jul 25.

PMID:
22833783
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Adaptive optics retinal imaging in the living mouse eye.

Geng Y, Dubra A, Yin L, Merigan WH, Sharma R, Libby RT, Williams DR.

Biomed Opt Express. 2012 Apr 1;3(4):715-34. doi: 10.1364/BOE.3.000715. Epub 2012 Mar 15.

PMID:
22574260
[PubMed]
Free PMC Article
16.

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.

Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, Anderson MG, Smith RS, Clark AF, Libby RT, John SW.

J Clin Invest. 2012 Apr 2;122(4):1246-61. doi: 10.1172/JCI61135. Epub 2012 Mar 19.

PMID:
22426214
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.

Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT.

Neurobiol Dis. 2012 May;46(2):393-401. doi: 10.1016/j.nbd.2012.02.003. Epub 2012 Feb 14.

PMID:
22353563
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Intrinsic axonal degeneration pathways are critical for glaucomatous damage.

Howell GR, Soto I, Libby RT, John SW.

Exp Neurol. 2013 Aug;246:54-61. doi: 10.1016/j.expneurol.2012.01.014. Epub 2012 Jan 18. Review.

PMID:
22285251
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data.

Howell GR, Walton DO, King BL, Libby RT, John SW.

BMC Genomics. 2011 Aug 24;12:429. doi: 10.1186/1471-2164-12-429.

PMID:
21864367
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina.

Harder JM, Libby RT.

Mol Neurodegener. 2011 Jul 15;6:50. doi: 10.1186/1750-1326-6-50.

PMID:
21762490
[PubMed]
Free PMC Article

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