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Treatment of human intestinal cryptosporidiosis: A review of published clinical trials.
Diptyanusa A, Sari IP. Diptyanusa A, et al. Int J Parasitol Drugs Drug Resist. 2021 Dec;17:128-138. doi: 10.1016/j.ijpddr.2021.09.001. Epub 2021 Sep 21. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34562754 Free PMC article. Review.
A total of 42 studies consisting of the use of nitazoxanide, paromomycin, macrolides, somatostatin analogues, letrazuril, albendazole, rifaximin, miltefosine, clofazimine, and colostrum were included in the review. ...
A total of 42 studies consisting of the use of nitazoxanide, paromomycin, macrolides, somatostatin analogues, letrazuril, albendazole …
A phase I study of letrazuril in AIDS-related cryptosporidiosis.
Harris M, Deutsch G, MacLean JD, Tsoukas CM. Harris M, et al. AIDS. 1994 Aug;8(8):1109-13. doi: 10.1097/00002030-199408000-00011. AIDS. 1994. PMID: 7986407 Clinical Trial.
Here we aim to determine the safety, tolerance, and clinical effect of letrazuril in the treatment of AIDS-related Cryptosporidiosis. DESIGN: A prospective, open-label study of letrazuril was performed. ...CONCLUSION: Fifty per cent of the AIDS patients in this stud …
Here we aim to determine the safety, tolerance, and clinical effect of letrazuril in the treatment of AIDS-related Cryptosporidiosis. …
Pilot studies of azithromycin, letrazuril and paromomycin in the treatment of cryptosporidiosis.
Blanshard C, Shanson DC, Gazzard BG. Blanshard C, et al. Int J STD AIDS. 1997 Feb;8(2):124-9. doi: 10.1258/0956462971919543. Int J STD AIDS. 1997. PMID: 9061412
Azithromycin 500 mg daily was ineffective. Letrazuril 150-200 mg daily was associated with an improvement in symptoms in 40% of patients treated and cessation of excretion of cryptosporidial oocysts in the stool in 70%; however biopsies remained positive. ...Dose escalatio …
Azithromycin 500 mg daily was ineffective. Letrazuril 150-200 mg daily was associated with an improvement in symptoms in 40% of patie …
Treatment with letrazuril of refractory cryptosporidial diarrhea complicating AIDS.
Loeb M, Walach C, Phillips J, Fong I, Salit I, Rachlis A, Walmsley S. Loeb M, et al. J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Sep 1;10(1):48-53. J Acquir Immune Defic Syndr Hum Retrovirol. 1995. PMID: 7648284 Clinical Trial.
Thirty-five AIDS patients (mean CD4 count 44 x 10(6)/L) with chronic cryptosporidiosis were treated with letrazuril at an initial oral daily dose of 50 mg in an open-label Phase I prospective trial. ...Of the responders, 15 (65%) had a clinical relapse with worsening diarr …
Thirty-five AIDS patients (mean CD4 count 44 x 10(6)/L) with chronic cryptosporidiosis were treated with letrazuril at an initial ora …
Successful treatment of AIDS-related cryptosporidial sclerosing cholangitis.
Hamour AA, Bonnington A, Hawthorne B, Wilkins EG. Hamour AA, et al. AIDS. 1993 Nov;7(11):1449-51. doi: 10.1097/00002030-199311000-00007. AIDS. 1993. PMID: 8280410
We evaluated the efficiency of the combination of paromomycin and letrazuril in the treatment of this condition. CASE REPORT: We report a case of cryptosporidial cholangitis in a patient with AIDS who responded to treatment with intravenous paromomycin followed by oral …
We evaluated the efficiency of the combination of paromomycin and letrazuril in the treatment of this condition. CASE REPORT: We repo …