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Results: 20

1.

Oncometabolites-driven tumorigenesis: From genetics to targeted therapy.

Morin A, Letouzé E, Gimenez-Roqueplo AP, Favier J.

Int J Cancer. 2014 Aug 14. doi: 10.1002/ijc.29080. [Epub ahead of print]

PMID:
25124653
[PubMed - as supplied by publisher]
2.

EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype.

Rebouissou S, Bernard-Pierrot I, de Reyniès A, Lepage ML, Krucker C, Chapeaublanc E, Hérault A, Kamoun A, Caillault A, Letouzé E, Elarouci N, Neuzillet Y, Denoux Y, Molinié V, Vordos D, Laplanche A, Maillé P, Soyeux P, Ofualuka K, Reyal F, Biton A, Sibony M, Paoletti X, Southgate J, Benhamou S, Lebret T, Allory Y, Radvanyi F.

Sci Transl Med. 2014 Jul 9;6(244):244ra91. doi: 10.1126/scitranslmed.3008970.

PMID:
25009231
[PubMed - in process]
3.

High-resolution analysis of DNA copy number alterations in rectal cancer : Correlation with metastasis, survival, and mRNA expression.

Doyen J, Letouzé E, Marisa L, de Reyniès A, Milano G, Etienne-Grimaldi MC, Olschwang S, Gaedcke J, Ghadimi M, Gérard JP.

Strahlenther Onkol. 2014 Apr 26. [Epub ahead of print]

PMID:
24770938
[PubMed - as supplied by publisher]
4.

SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma.

Hadoux J, Favier J, Scoazec JY, Leboulleux S, Al Ghuzlan A, Caramella C, Déandreis D, Borget I, Loriot C, Chougnet C, Letouzé E, Young J, Amar L, Bertherat J, Libé R, Dumont F, Deschamps F, Schlumberger M, Gimenez-Roqueplo AP, Baudin E.

Int J Cancer. 2014 Apr 18. doi: 10.1002/ijc.28913. [Epub ahead of print]

PMID:
24752622
[PubMed - as supplied by publisher]
5.

Integrated genomic characterization of adrenocortical carcinoma.

Assié G, Letouzé E, Fassnacht M, Jouinot A, Luscap W, Barreau O, Omeiri H, Rodriguez S, Perlemoine K, René-Corail F, Elarouci N, Sbiera S, Kroiss M, Allolio B, Waldmann J, Quinkler M, Mannelli M, Mantero F, Papathomas T, De Krijger R, Tabarin A, Kerlan V, Baudin E, Tissier F, Dousset B, Groussin L, Amar L, Clauser E, Bertagna X, Ragazzon B, Beuschlein F, Libé R, de Reyniès A, Bertherat J.

Nat Genet. 2014 Jun;46(6):607-12. doi: 10.1038/ng.2953. Epub 2014 Apr 20.

PMID:
24747642
[PubMed - indexed for MEDLINE]
6.

Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation.

Pilati C, Letouzé E, Nault JC, Imbeaud S, Boulai A, Calderaro J, Poussin K, Franconi A, Couchy G, Morcrette G, Mallet M, Taouji S, Balabaud C, Terris B, Canal F, Paradis V, Scoazec JY, de Muret A, Guettier C, Bioulac-Sage P, Chevet E, Calvo F, Zucman-Rossi J.

Cancer Cell. 2014 Apr 14;25(4):428-41. doi: 10.1016/j.ccr.2014.03.005.

PMID:
24735922
[PubMed - indexed for MEDLINE]
7.

Unsuspected task for an old team: succinate, fumarate and other Krebs cycle acids in metabolic remodeling.

Bénit P, Letouzé E, Rak M, Aubry L, Burnichon N, Favier J, Gimenez-Roqueplo AP, Rustin P.

Biochim Biophys Acta. 2014 Aug;1837(8):1330-7. doi: 10.1016/j.bbabio.2014.03.013. Epub 2014 Mar 31.

PMID:
24699309
[PubMed - in process]
8.

[Mutations in succinate dehydrogenase and DNA methylation].

Favier J, Letouzé E.

Med Sci (Paris). 2013 Dec;29(12):1092-4. doi: 10.1051/medsci/20132912010. Epub 2013 Dec 20. French. No abstract available.

PMID:
24356137
[PubMed - indexed for MEDLINE]
9.

Contrast enhancement in 1p/19q-codeleted anaplastic oligodendrogliomas is associated with 9p loss, genomic instability, and angiogenic gene expression.

Reyes-Botero G, Dehais C, Idbaih A, Martin-Duverneuil N, Lahutte M, Carpentier C, Letouzé E, Chinot O, Loiseau H, Honnorat J, Ramirez C, Moyal E, Figarella-Branger D, Ducray F; POLA Network.

Neuro Oncol. 2014 May;16(5):662-70. doi: 10.1093/neuonc/not235. Epub 2013 Dec 18.

PMID:
24353325
[PubMed - in process]
10.

SDH mutations establish a hypermethylator phenotype in paraganglioma.

Letouzé E, Martinelli C, Loriot C, Burnichon N, Abermil N, Ottolenghi C, Janin M, Menara M, Nguyen AT, Benit P, Buffet A, Marcaillou C, Bertherat J, Amar L, Rustin P, De Reyniès A, Gimenez-Roqueplo AP, Favier J.

Cancer Cell. 2013 Jun 10;23(6):739-52. doi: 10.1016/j.ccr.2013.04.018. Epub 2013 May 23.

PMID:
23707781
[PubMed - indexed for MEDLINE]
Free Article
11.

Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.

Rouault A, Banneau G, Macgrogan G, Jones N, Elarouci N, Barouk-Simonet E, Venat L, Coupier I, Letouzé E, de Reyniès A, Bonnet F, Iggo R, Sévenet N, Longy M.

PLoS One. 2012;7(12):e52079. doi: 10.1371/journal.pone.0052079. Epub 2012 Dec 21.

PMID:
23284877
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Towards a "Lyon molecular signature" to individualize the treatment of rectal cancer. Prognostic analysis of a prospective cohort of 94 rectal cancers T1-2-3 Nx MO to be the basis of a molecular signature.

Gérard JP, Baulieux J, Doyen J, Gal J, Letouze E, Olschwang S, Chapet O, Romestaing P.

Cancer Radiother. 2012 Dec;16(8):688-96. doi: 10.1016/j.canrad.2012.09.003. Epub 2012 Nov 13.

PMID:
23153504
[PubMed - indexed for MEDLINE]
13.

Recurrent inactivating mutations of ARID2 in non-small cell lung carcinoma.

Manceau G, Letouzé E, Guichard C, Didelot A, Cazes A, Corté H, Fabre E, Pallier K, Imbeaud S, Le Pimpec-Barthes F, Zucman-Rossi J, Laurent-Puig P, Blons H.

Int J Cancer. 2013 May 1;132(9):2217-21. doi: 10.1002/ijc.27900. Epub 2012 Nov 20.

PMID:
23047306
[PubMed - indexed for MEDLINE]
14.

Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma.

Burnichon N, Buffet A, Parfait B, Letouzé E, Laurendeau I, Loriot C, Pasmant E, Abermil N, Valeyrie-Allanore L, Bertherat J, Amar L, Vidaud D, Favier J, Gimenez-Roqueplo AP.

Hum Mol Genet. 2012 Dec 15;21(26):5397-405. doi: 10.1093/hmg/dds374. Epub 2012 Sep 6.

PMID:
22962301
[PubMed - indexed for MEDLINE]
Free Article
15.

Identity by descent mapping of founder mutations in cancer using high-resolution tumor SNP data.

Letouzé E, Sow A, Petel F, Rosati R, Figueiredo BC, Burnichon N, Gimenez-Roqueplo AP, Lalli E, de Reyniès A.

PLoS One. 2012;7(5):e35897. doi: 10.1371/journal.pone.0035897. Epub 2012 May 2.

PMID:
22567117
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma.

Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, Bioulac-Sage P, Letexier M, Degos F, Clément B, Balabaud C, Chevet E, Laurent A, Couchy G, Letouzé E, Calvo F, Zucman-Rossi J.

Nat Genet. 2012 May 6;44(6):694-8. doi: 10.1038/ng.2256.

PMID:
22561517
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

SNP array profiling of childhood adrenocortical tumors reveals distinct pathways of tumorigenesis and highlights candidate driver genes.

Letouzé E, Rosati R, Komechen H, Doghman M, Marisa L, Flück C, de Krijger RR, van Noesel MM, Mas JC, Pianovski MA, Zambetti GP, Figueiredo BC, Lalli E.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1284-93. doi: 10.1210/jc.2012-1184. Epub 2012 Apr 26.

PMID:
22539591
[PubMed - indexed for MEDLINE]
18.

CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma.

Rebouissou S, Hérault A, Letouzé E, Neuzillet Y, Laplanche A, Ofualuka K, Maillé P, Leroy K, Riou A, Lepage ML, Vordos D, de la Taille A, Denoux Y, Sibony M, Guyon F, Lebret T, Benhamou S, Allory Y, Radvanyi F.

J Pathol. 2012 Jul;227(3):315-24. doi: 10.1002/path.4017. Epub 2012 May 8.

PMID:
22422578
[PubMed - indexed for MEDLINE]
19.

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis.

Letouzé E, Allory Y, Bollet MA, Radvanyi F, Guyon F.

Genome Biol. 2010;11(7):R76. doi: 10.1186/gb-2010-11-7-r76. Epub 2010 Jul 22.

PMID:
20649963
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

Shepherd NE, Hoang HN, Desai VS, Letouze E, Young PR, Fairlie DP.

J Am Chem Soc. 2006 Oct 11;128(40):13284-9.

PMID:
17017810
[PubMed - indexed for MEDLINE]

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