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Results: 1 to 20 of 221


Large oligomeric complex structures can be computationally assembled by efficiently combining docked interfaces.

Dietzen M, Kalinina OV, Taškova K, Kneissl B, Hildebrandt AK, Jaenicke E, Decker H, Lengauer T, Hildebrandt A.

Proteins. 2015 Aug 6. doi: 10.1002/prot.24873. [Epub ahead of print]


Proviral DNA as a Target for HIV-1 Resistance Analysis.

Lübke N, Di Cristanziano V, Sierra S, Knops E, Schülter E, Jensen B, Oette M, Lengauer T, Kaiser R.

Intervirology. 2015;58(3):184-9. doi: 10.1159/000431093. Epub 2015 Jun 27.


ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.

Karp PD, Berger B, Kovats D, Lengauer T, Linial M, Sabeti P, Hide W, Rost B.

F1000Res. 2015 Jan 15;4:12. doi: 10.12688/f1000research.6038.1. eCollection 2015.


A general concept for consistent documentation of computational analyses.

Ebert P, Müller F, Nordström K, Lengauer T, Schulz MH.

Database (Oxford). 2015 Jun 8;2015:bav050. doi: 10.1093/database/bav050. Print 2015.


Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc.

Sierra S, Dybowski JN, Pironti A, Heider D, Güney L, Thielen A, Reuter S, Esser S, Fätkenheuer G, Lengauer T, Hoffmann D, Pfister H, Jensen B, Kaiser R.

PLoS One. 2015 May 13;10(5):e0125502. doi: 10.1371/journal.pone.0125502. eCollection 2015.


Effects of sequence alterations on results from genotypic tropism testing.

Pironti A, Sierra S, Kaiser R, Lengauer T, Pfeifer N.

J Clin Virol. 2015 Apr;65:68-73. doi: 10.1016/j.jcv.2015.02.006. Epub 2015 Feb 10.


How to write a presubmission inquiry.

Lengauer T, Nussinov R.

PLoS Comput Biol. 2015 Feb 26;11(2):e1004098. doi: 10.1371/journal.pcbi.1004098. eCollection 2015 Feb. No abstract available.


Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus.

Karp PD, Berger B, Kovats D, Lengauer T, Linial M, Sabeti P, Hide W, Rost B.

Bioinformatics. 2015 Feb 15;31(4):616-7. doi: 10.1093/bioinformatics/btv019. Epub 2015 Feb 2.


Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences.

Pironti A, Pfeifer N, Kaiser R, Walter H, Lengauer T.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19743. doi: 10.7448/IAS.17.4.19743. eCollection 2014.


Comprehensive analysis of DNA methylation data with RnBeads.

Assenov Y, Müller F, Lutsik P, Walter J, Lengauer T, Bock C.

Nat Methods. 2014 Nov;11(11):1138-40. doi: 10.1038/nmeth.3115. Epub 2014 Sep 28.


Association between HIV-1 coreceptor usage and resistance to broadly neutralizing antibodies.

Pfeifer N, Walter H, Lengauer T.

J Acquir Immune Defic Syndr. 2014 Oct 1;67(2):107-12. doi: 10.1097/QAI.0000000000000283.


BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives.

Becker D, Lutsik P, Ebert P, Bock C, Lengauer T, Walter J.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W501-7. doi: 10.1093/nar/gku457. Epub 2014 May 29.


Personalized HIV therapy to control drug resistance.

Lengauer T, Pfeifer N, Kaiser R.

Drug Discov Today Technol. 2014 Mar;11:57-64. doi: 10.1016/j.ddtec.2014.02.004. Review.


Inferring short-range linkage information from sequencing chromatograms.

Beggel B, Neumann-Fraune M, Kaiser R, Verheyen J, Lengauer T.

PLoS One. 2013 Dec 20;8(12):e81687. doi: 10.1371/journal.pone.0081687. eCollection 2013.


Efficient computation of root mean square deviations under rigid transformations.

Hildebrandt AK, Dietzen M, Lengauer T, Lenhof HP, Althaus E, Hildebrandt A.

J Comput Chem. 2014 Apr 15;35(10):765-71. doi: 10.1002/jcc.23513. Epub 2013 Dec 19.


Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.

Beggel B, Münk C, Däumer M, Hauck K, Häussinger D, Lengauer T, Erhardt A.

J Viral Hepat. 2013 Dec;20(12):882-9. doi: 10.1111/jvh.12110. Epub 2013 Jun 7.


Ambulatory care for HIV-infected patients: differences in outcomes between hospital-based units and private practices: analysis of the RESINA cohort.

Oette M, Reuter S, Kaiser R, Jensen B, Lengauer T, Fätkenheuer G, Knechten H, Hower M, Sagir A, Pfister H, Häussinger D; RESINA study group.

Eur J Med Res. 2013 Nov 21;18:48. doi: 10.1186/2047-783X-18-48.


[Importance of bioinformatics in personalised medicine].

Lengauer T.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Nov;56(11):1489-94. doi: 10.1007/s00103-013-1819-x. German.


Sensitive detection of viral transcripts in human tumor transcriptomes.

Schelhorn SE, Fischer M, Tolosi L, Altmüller J, Nürnberg P, Pfister H, Lengauer T, Berthold F.

PLoS Comput Biol. 2013;9(10):e1003228. doi: 10.1371/journal.pcbi.1003228. Epub 2013 Oct 3.

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