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Effects of sequence alterations on results from genotypic tropism testing.

Pironti A, Sierra S, Kaiser R, Lengauer T, Pfeifer N.

J Clin Virol. 2015 Apr;65:68-73. doi: 10.1016/j.jcv.2015.02.006. Epub 2015 Feb 10.

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How to write a presubmission inquiry.

Lengauer T, Nussinov R.

PLoS Comput Biol. 2015 Feb 26;11(2):e1004098. doi: 10.1371/journal.pcbi.1004098. eCollection 2015 Feb. No abstract available.


Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus.

Karp PD, Berger B, Kovats D, Lengauer T, Linial M, Sabeti P, Hide W, Rost B.

Bioinformatics. 2015 Feb 15;31(4):616-7. doi: 10.1093/bioinformatics/btv019. Epub 2015 Feb 2.


Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences.

Pironti A, Pfeifer N, Kaiser R, Walter H, Lengauer T.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19743. doi: 10.7448/IAS.17.4.19743. eCollection 2014.


Comprehensive analysis of DNA methylation data with RnBeads.

Assenov Y, Müller F, Lutsik P, Walter J, Lengauer T, Bock C.

Nat Methods. 2014 Nov;11(11):1138-40. doi: 10.1038/nmeth.3115. Epub 2014 Sep 28.


Association between HIV-1 coreceptor usage and resistance to broadly neutralizing antibodies.

Pfeifer N, Walter H, Lengauer T.

J Acquir Immune Defic Syndr. 2014 Oct 1;67(2):107-12. doi: 10.1097/QAI.0000000000000283.


BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives.

Becker D, Lutsik P, Ebert P, Bock C, Lengauer T, Walter J.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W501-7. doi: 10.1093/nar/gku457. Epub 2014 May 29.


Personalized HIV therapy to control drug resistance.

Lengauer T, Pfeifer N, Kaiser R.

Drug Discov Today Technol. 2014 Mar;11:57-64. doi: 10.1016/j.ddtec.2014.02.004. Review.


Inferring short-range linkage information from sequencing chromatograms.

Beggel B, Neumann-Fraune M, Kaiser R, Verheyen J, Lengauer T.

PLoS One. 2013 Dec 20;8(12):e81687. doi: 10.1371/journal.pone.0081687. eCollection 2013.


Efficient computation of root mean square deviations under rigid transformations.

Hildebrandt AK, Dietzen M, Lengauer T, Lenhof HP, Althaus E, Hildebrandt A.

J Comput Chem. 2013 Dec 19. doi: 10.1002/jcc.23513. [Epub ahead of print]


Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.

Beggel B, Münk C, Däumer M, Hauck K, Häussinger D, Lengauer T, Erhardt A.

J Viral Hepat. 2013 Dec;20(12):882-9. doi: 10.1111/jvh.12110. Epub 2013 Jun 7.


Ambulatory care for HIV-infected patients: differences in outcomes between hospital-based units and private practices: analysis of the RESINA cohort.

Oette M, Reuter S, Kaiser R, Jensen B, Lengauer T, Fätkenheuer G, Knechten H, Hower M, Sagir A, Pfister H, Häussinger D; RESINA study group.

Eur J Med Res. 2013 Nov 21;18:48. doi: 10.1186/2047-783X-18-48.


[Importance of bioinformatics in personalised medicine].

Lengauer T.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Nov;56(11):1489-94. doi: 10.1007/s00103-013-1819-x. German.


Sensitive detection of viral transcripts in human tumor transcriptomes.

Schelhorn SE, Fischer M, Tolosi L, Altmüller J, Nürnberg P, Pfister H, Lengauer T, Berthold F.

PLoS Comput Biol. 2013;9(10):e1003228. doi: 10.1371/journal.pcbi.1003228. Epub 2013 Oct 3.


DNA methylation patterns facilitate the identification of microRNA transcription start sites: a brain-specific study.

Bhadra T, Bhattacharyya M, Feuerbach L, Lengauer T, Bandyopadhyay S.

PLoS One. 2013 Jun 24;8(6):e66722. doi: 10.1371/journal.pone.0066722. Print 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/dd8f4acc-3859-46e2-9136-20b6b4d08d21.


A method for finding consensus breakpoints in the cancer genome from copy number data.

Toloşi L, Theißen J, Halachev K, Hero B, Berthold F, Lengauer T.

Bioinformatics. 2013 Jul 15;29(14):1793-800. doi: 10.1093/bioinformatics/btt300. Epub 2013 May 28.


Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage.

Bozek K, Lengauer T, Sierra S, Kaiser R, Domingues FS.

PLoS Comput Biol. 2013;9(3):e1002977. doi: 10.1371/journal.pcbi.1002977. Epub 2013 Mar 21.


Deep sequencing reveals mutagenic effects of ribavirin during monotherapy of hepatitis C virus genotype 1-infected patients.

Dietz J, Schelhorn SE, Fitting D, Mihm U, Susser S, Welker MW, Füller C, Däumer M, Teuber G, Wedemeyer H, Berg T, Lengauer T, Zeuzem S, Herrmann E, Sarrazin C.

J Virol. 2013 Jun;87(11):6172-81. doi: 10.1128/JVI.02778-12. Epub 2013 Mar 27.


Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues.

Simmer F, Brinkman AB, Assenov Y, Matarese F, Kaan A, Sabatino L, Villanueva A, Huertas D, Esteller M, Lengauer T, Bock C, Colantuoni V, Altucci L, Stunnenberg HG.

Epigenetics. 2012 Dec 1;7(12):1355-67. doi: 10.4161/epi.22562. Epub 2012 Oct 18.

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