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Results: 14

1.

DNA methylation markers for early detection of women's cancer: promise and challenges.

Wittenberger T, Sleigh S, Reisel D, Zikan M, Wahl B, Alunni-Fabbroni M, Jones A, Evans I, Koch J, Paprotka T, Lempiäinen H, Rujan T, Rack B, Cibula D, Widschwendter M.

Epigenomics. 2014 Jun;6(3):311-27. doi: 10.2217/epi.14.20.

PMID:
25111485
[PubMed - in process]
Free Article
2.

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG.

Toxicol Sci. 2014 Jun;139(2):501-11. doi: 10.1093/toxsci/kfu038. Epub 2014 Apr 1.

PMID:
24690595
[PubMed - in process]
3.

Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.

Unterberger EB, Eichner J, Wrzodek C, Lempiäinen H, Luisier R, Terranova R, Metzger U, Plummer S, Knorpp T, Braeuning A, Moggs J, Templin MF, Honndorf V, Piotto M, Zell A, Schwarz M.

Int J Cancer. 2014 Oct 1;135(7):1574-85. doi: 10.1002/ijc.28798. Epub 2014 Mar 3.

PMID:
24535843
[PubMed - indexed for MEDLINE]
4.

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, Meehan RR.

Nucleic Acids Res. 2013 Jun;41(11):5639-54. doi: 10.1093/nar/gkt232. Epub 2013 Apr 17.

PMID:
23598998
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.

Lempiäinen H, Couttet P, Bolognani F, Müller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, Brasa S, Kalteis M, Marcellin M, Giudicelli F, Braeuning A, Morawiec L, Zamurovic N, Längle U, Scheer N, Schübeler D, Goodman J, Chibout SD, Marlowe J, Theil D, Heard DJ, Grenet O, Zell A, Templin MF, Meehan RR, Wolf RC, Elcombe CR, Schwarz M, Moulin P, Terranova R, Moggs JG.

Toxicol Sci. 2013 Feb;131(2):375-86. doi: 10.1093/toxsci/kfs303. Epub 2012 Oct 22.

PMID:
23091169
[PubMed - indexed for MEDLINE]
Free Article
6.

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.

Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR.

Genome Biol. 2012 Oct 3;13(10):R93. doi: 10.1186/gb-2012-13-10-r93.

PMID:
23034186
[PubMed - in process]
Free PMC Article
7.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R.

PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216.

PMID:
21455306
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Growth control and ribosome biogenesis.

Lempiäinen H, Shore D.

Curr Opin Cell Biol. 2009 Dec;21(6):855-63. doi: 10.1016/j.ceb.2009.09.002. Epub 2009 Sep 30. Review. Erratum in: Curr Opin Cell Biol. 2010 Aug;22(4):555.

PMID:
19796927
[PubMed - indexed for MEDLINE]
9.

Emerging common themes in regulation of PIKKs and PI3Ks.

Lempiäinen H, Halazonetis TD.

EMBO J. 2009 Oct 21;28(20):3067-73. doi: 10.1038/emboj.2009.281. Epub 2009 Sep 24. Review.

PMID:
19779456
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling.

Lempiäinen H, Uotila A, Urban J, Dohnal I, Ammerer G, Loewith R, Shore D.

Mol Cell. 2009 Mar 27;33(6):704-16. doi: 10.1016/j.molcel.2009.01.034.

PMID:
19328065
[PubMed - indexed for MEDLINE]
Free Article
11.

Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response.

Hosiner D, Lempiäinen H, Reiter W, Urban J, Loewith R, Ammerer G, Schweyen R, Shore D, Schüller C.

Mol Biol Cell. 2009 Feb;20(3):1048-57. doi: 10.1091/mbc.E08-04-0438. Epub 2008 Dec 10.

PMID:
19073887
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Occurrence of virulence factors among human intestinal enterococcal isolates.

Lempiäinen H, Kinnunen K, Mertanen A, von Wright A.

Lett Appl Microbiol. 2005;41(4):341-4.

PMID:
16162141
[PubMed - indexed for MEDLINE]
13.

Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein.

Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, Carlberg C.

Mol Endocrinol. 2005 Sep;19(9):2258-72. Epub 2005 May 19.

PMID:
15905360
[PubMed - indexed for MEDLINE]
14.

Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.

Frank C, Molnár F, Matilainen M, Lempiäinen H, Carlberg C.

J Biol Chem. 2004 Aug 6;279(32):33558-66. Epub 2004 May 19.

PMID:
15151997
[PubMed - indexed for MEDLINE]
Free Article

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