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Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens.

Vijendravarma RK, Narasimha S, Chakrabarti S, Babin A, Kolly S, Lemaitre B, Kawecki TJ.

Ecol Lett. 2015 Aug 6. doi: 10.1111/ele.12490. [Epub ahead of print]


The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial.

Huttner A, Dayer JA, Yerly S, Combescure C, Auderset F, Desmeules J, Eickmann M, Finckh A, Goncalves AR, Hooper JW, Kaya G, Krähling V, Kwilas S, Lemaître B, Matthey A, Silvera P, Becker S, Fast PE, Moorthy V, Kieny MP, Kaiser L, Siegrist CA; VSV-Ebola Consortium.

Lancet Infect Dis. 2015 Aug 3. pii: S1473-3099(15)00154-1. doi: 10.1016/S1473-3099(15)00154-1. [Epub ahead of print]


Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence.

Bou Sleiman MS, Osman D, Massouras A, Hoffmann AA, Lemaitre B, Deplancke B.

Nat Commun. 2015 Jul 27;6:7829. doi: 10.1038/ncomms8829.


Different flavors of Toll guide olfaction.

Neyen C, Lemaitre B.

Trends Immunol. 2015 Aug;36(8):439-41. doi: 10.1016/ Epub 2015 Jul 3.


From Embryo to Adult: Hematopoiesis along the Drosophila Life Cycle.

Ramond E, Meister M, Lemaitre B.

Dev Cell. 2015 May 26;33(4):367-8. doi: 10.1016/j.devcel.2015.05.002.


Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties.

Speciale I, Paciello I, Fazio LL, Sturiale L, Palmigiano A, Lanzetta R, Parrilli M, Garozzo D, Lemaitre B, Bernardini ML, Molinaro A, De Castro C.

Carbohydr Res. 2015 Aug 14;412:20-7. doi: 10.1016/j.carres.2015.04.017. Epub 2015 May 1.


X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.

Leone P, Bebeacua C, Opota O, Kellenberger C, Klaholz B, Orlov I, Cambillau C, Lemaitre B, Roussel A.

J Biol Chem. 2015 May 22;290(21):13191-201. doi: 10.1074/jbc.M115.646109. Epub 2015 Apr 5.


Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe - Preliminary Report.

Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, Fernandes JF, Yerly S, Dayer JA, Kraehling V, Kasonta R, Adegnika AA, Altfeld M, Auderset F, Bache EB, Biedenkopf N, Borregaard S, Brosnahan JS, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling SK, Finckh A, Goncalves AR, Grobusch MP, Hooper J, Jambrecina A, Kabwende AL, Kaya G, Kimani D, Lell B, Lemaître B, Lohse AW, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl FR, Staines HM, Strecker T, Stubbe HC, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny MP, Bejon P, Kremsner PG, Addo MM, Siegrist CA.

N Engl J Med. 2015 Apr 1. [Epub ahead of print]


Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont.

Paredes JC, Herren JK, Schüpfer F, Marin R, Claverol S, Kuo CH, Lemaitre B, Béven L.

MBio. 2015 Mar 31;6(2). pii: e02437-14. doi: 10.1128/mBio.02437-14.


The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster.

Bretscher AJ, Honti V, Binggeli O, Burri O, Poidevin M, Kurucz É, Zsámboki J, Andó I, Lemaitre B.

Biol Open. 2015 Feb 13;4(3):355-63. doi: 10.1242/bio.201410595.


The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects.

Neyen C, Binggeli O, Roversi P, Bertin L, Sleiman MB, Lemaitre B.

Dev Comp Immunol. 2015 Jun;50(2):166-74. doi: 10.1016/j.dci.2014.12.011. Epub 2014 Dec 24.


Transforming growth factor β/activin signaling functions as a sugar-sensing feedback loop to regulate digestive enzyme expression.

Chng WB, Bou Sleiman MS, Schüpfer F, Lemaitre B.

Cell Rep. 2014 Oct 9;9(1):336-48. doi: 10.1016/j.celrep.2014.08.064. Epub 2014 Oct 2.


The Drosophila MAPK p38c regulates oxidative stress and lipid homeostasis in the intestine.

Chakrabarti S, Poidevin M, Lemaitre B.

PLoS Genet. 2014 Sep 25;10(9):e1004659. doi: 10.1371/journal.pgen.1004659. eCollection 2014 Sep.


Insect endosymbiont proliferation is limited by lipid availability.

Herren JK, Paredes JC, Schüpfer F, Arafah K, Bulet P, Lemaitre B.

Elife. 2014 Jul 15;3:e02964. doi: 10.7554/eLife.02964.


Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology.

Broderick NA, Buchon N, Lemaitre B.

MBio. 2014 May 27;5(3):e01117-14. doi: 10.1128/mBio.01117-14.


Prophenoloxidase activation is required for survival to microbial infections in Drosophila.

Binggeli O, Neyen C, Poidevin M, Lemaitre B.

PLoS Pathog. 2014 May 1;10(5):e1004067. doi: 10.1371/journal.ppat.1004067. eCollection 2014 May.


Methods to study Drosophila immunity.

Neyen C, Bretscher AJ, Binggeli O, Lemaitre B.

Methods. 2014 Jun 15;68(1):116-28. doi: 10.1016/j.ymeth.2014.02.023. Epub 2014 Mar 12. Review.


The digestive tract of Drosophila melanogaster.

Lemaitre B, Miguel-Aliaga I.

Annu Rev Genet. 2013;47:377-404. doi: 10.1146/annurev-genet-111212-133343. Review.


Functional analysis of PGRP-LA in Drosophila immunity.

Gendrin M, Zaidman-Rémy A, Broderick NA, Paredes J, Poidevin M, Roussel A, Lemaitre B.

PLoS One. 2013 Jul 26;8(7):e69742. doi: 10.1371/journal.pone.0069742. Print 2013.


Crystallization and preliminary X-ray analysis of monalysin, a novel β-pore-forming toxin from the entomopathogen Pseudomonas entomophila.

Blemont M, Vincentelli R, Kellenberger C, Opota O, Lemaitre B, Roussel A, Leone P.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):930-3. doi: 10.1107/S174430911301885X. Epub 2013 Jul 27.

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