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Results: 12

1.

Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo.

Posch C, Moslehi H, Feeney L, Green GA, Ebaee A, Feichtenschlager V, Chong K, Peng L, Dimon MT, Phillips T, Daud AI, McCalmont TH, LeBoit PE, Ortiz-Urda S.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4015-20. doi: 10.1073/pnas.1216013110. Epub 2013 Feb 19.

PMID:
23431193
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mosaic activating RAS mutations in nevus sebaceus and nevus sebaceus syndrome.

Sun BK, Saggini A, Sarin KY, Kim J, Benjamin L, LeBoit PE, Khavari PA.

J Invest Dermatol. 2013 Mar;133(3):824-7. doi: 10.1038/jid.2012.377. Epub 2012 Oct 25. No abstract available.

PMID:
23096709
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.

Wang NJ, Sanborn Z, Arnett KL, Bayston LJ, Liao W, Proby CM, Leigh IM, Collisson EA, Gordon PB, Jakkula L, Pennypacker S, Zou Y, Sharma M, North JP, Vemula SS, Mauro TM, Neuhaus IM, Leboit PE, Hur JS, Park K, Huh N, Kwok PY, Arron ST, Massion PP, Bale AE, Haussler D, Cleaver JE, Gray JW, Spellman PT, South AP, Aster JC, Blacklow SC, Cho RJ.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17761-6. doi: 10.1073/pnas.1114669108. Epub 2011 Oct 17.

PMID:
22006338
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Temporal dissection of tumorigenesis in primary cancers.

Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC, Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho RJ.

Cancer Discov. 2011 Jul;1(2):137-43. doi: 10.1158/2159-8290.CD-11-0028. Epub 2011 Jun 29.

PMID:
21984974
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma.

Jalas JR, Vemula S, Bezrookove V, Leboit PE, Simko JP, Bastian BC.

Am J Surg Pathol. 2011 Sep;35(9):1413-8. doi: 10.1097/PAS.0b013e31822280d8.

PMID:
21836492
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanoma.

Dalton SR, Gerami P, Kolaitis NA, Charzan S, Werling R, LeBoit PE, Bastian BC.

Am J Surg Pathol. 2010 Feb;34(2):231-7. doi: 10.1097/PAS.0b013e3181c805c4.

PMID:
20087158
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma.

North JP, Kageshita T, Pinkel D, LeBoit PE, Bastian BC.

J Invest Dermatol. 2008 Aug;128(8):2024-30. doi: 10.1038/jid.2008.41. Epub 2008 Mar 6.

PMID:
18323782
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Classifying melanocytic tumors based on DNA copy number changes.

Bastian BC, Olshen AB, LeBoit PE, Pinkel D.

Am J Pathol. 2003 Nov;163(5):1765-70.

PMID:
14578177
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas.

Bastian BC, Xiong J, Frieden IJ, Williams ML, Chou P, Busam K, Pinkel D, LeBoit PE.

Am J Pathol. 2002 Oct;161(4):1163-9.

PMID:
12368190
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features.

Bastian BC, LeBoit PE, Pinkel D.

Am J Pathol. 2000 Sep;157(3):967-72.

PMID:
10980135
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Thick-section fluorescence in situ hybridization on formalin-fixed, paraffin-embedded archival tissue provides a histogenetic profile.

Thompson CT, LeBoit PE, Nederlof PM, Gray JW.

Am J Pathol. 1994 Feb;144(2):237-43.

PMID:
8311111
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pathology: lymphocyte gene rearrangements-a new technique in the diagnosis of lymphoma.

Leboit PE, Parslow TG.

West J Med. 1986 Sep;145(3):370-1. No abstract available.

PMID:
18750066
[PubMed]
Free PMC Article

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