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Results: 1 to 20 of 326

1.

Prioritisation and network analysis of Crohn's disease susceptibility genes.

Muraro D, Lauffenburger DA, Simmons A.

PLoS One. 2014 Sep 30;9(9):e108624. doi: 10.1371/journal.pone.0108624. eCollection 2014.

PMID:
25268122
[PubMed - in process]
Free PMC Article
2.

Reply to Azuaje: Predicting effective combined therapies for heterogeneous tumors.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4288. doi: 10.1073/pnas.1415737111. Epub 2014 Sep 24. No abstract available.

PMID:
25253893
[PubMed - in process]
3.

Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC.

Tape CJ, Worboys JD, Sinclair J, Gourlay R, Vogt J, McMahon KM, Trost M, Lauffenburger DA, Lamont DJ, Jørgensen C.

Anal Chem. 2014 Oct 21;86(20):10296-302. doi: 10.1021/ac5025842. Epub 2014 Oct 2.

PMID:
25233145
[PubMed - in process]
4.

Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.

Palmer CD, Tomassilli J, Sirignano M, Tejeda MR, Arnold KB, Che D, Lauffenburger DA, Jost S, Allen T, Mayer KH, Altfeld M.

AIDS. 2014 Jul 4. [Epub ahead of print]

PMID:
25003719
[PubMed - as supplied by publisher]
5.

Intratumor heterogeneity alters most effective drugs in designed combinations.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10773-8. doi: 10.1073/pnas.1323934111. Epub 2014 Jul 7.

PMID:
25002493
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A microphysiological system model of therapy for liver micrometastases.

Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A.

Exp Biol Med (Maywood). 2014 Sep;239(9):1170-9. doi: 10.1177/1535370214532596. Epub 2014 May 12.

PMID:
24821820
[PubMed - in process]
7.

Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture.

Tape CJ, Norrie IC, Worboys JD, Lim L, Lauffenburger DA, Jørgensen C.

Mol Cell Proteomics. 2014 Jul;13(7):1866-76. doi: 10.1074/mcp.O113.037119. Epub 2014 May 12.

PMID:
24820872
[PubMed - in process]
8.

Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.

Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT.

Drug Discov Today. 2014 Jun;19(6):754-62. doi: 10.1016/j.drudis.2014.04.017. Epub 2014 May 2.

PMID:
24793141
[PubMed - in process]
9.

Microfluidic probe for single-cell analysis in adherent tissue culture.

Sarkar A, Kolitz S, Lauffenburger DA, Han J.

Nat Commun. 2014 Mar 5;5:3421. doi: 10.1038/ncomms4421.

PMID:
24594667
[PubMed - in process]
Free PMC Article
10.

Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.

Beste MT, Pfäffle-Doyle N, Prentice EA, Morris SN, Lauffenburger DA, Isaacson KB, Griffith LG.

Sci Transl Med. 2014 Feb 5;6(222):222ra16. doi: 10.1126/scitranslmed.3007988.

PMID:
24500404
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Addressing genetic tumor heterogeneity through computationally predictive combination therapy.

Zhao B, Pritchard JR, Lauffenburger DA, Hemann MT.

Cancer Discov. 2014 Feb;4(2):166-74. doi: 10.1158/2159-8290.CD-13-0465. Epub 2013 Dec 6.

PMID:
24318931
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.

Arneja A, Johnson H, Gabrovsek L, Lauffenburger DA, White FM.

J Immunol. 2014 Jan 1;192(1):123-35. doi: 10.4049/jimmunol.1302291. Epub 2013 Dec 2.

PMID:
24298013
[PubMed - indexed for MEDLINE]
13.

HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways.

Simmons RP, Scully EP, Groden EE, Arnold KB, Chang JJ, Lane K, Lifson J, Rosenberg E, Lauffenburger DA, Altfeld M.

AIDS. 2013 Oct 23;27(16):2505-17. doi: 10.1097/01.aids.0000432455.06476.bc.

PMID:
24096630
[PubMed - indexed for MEDLINE]
14.

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM.

Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2.

PMID:
24084984
[PubMed - indexed for MEDLINE]
15.

Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context.

Hang TC, Tedford NC, Reddy RJ, Rimchala T, Wells A, White FM, Kamm RD, Lauffenburger DA.

Mol Cell Proteomics. 2013 Dec;12(12):3704-18. doi: 10.1074/mcp.M113.030528. Epub 2013 Sep 9.

PMID:
24023389
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells.

Meyer AS, Miller MA, Gertler FB, Lauffenburger DA.

Sci Signal. 2013 Aug 6;6(287):ra66. doi: 10.1126/scisignal.2004155.

PMID:
23921085
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, MacBeath G.

Sci Signal. 2013 Jul 16;6(284):ra58. doi: 10.1126/scisignal.2003994.

PMID:
23861540
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Integrated network analyses for functional genomic studies in cancer.

Wilson JL, Hemann MT, Fraenkel E, Lauffenburger DA.

Semin Cancer Biol. 2013 Aug;23(4):213-8. doi: 10.1016/j.semcancer.2013.06.004. Epub 2013 Jun 27. Review.

PMID:
23811269
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Models of signalling networks - what cell biologists can gain from them and give to them.

Janes KA, Lauffenburger DA.

J Cell Sci. 2013 May 1;126(Pt 9):1913-21. doi: 10.1242/jcs.112045. Review.

PMID:
23720376
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.

Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9776-81. doi: 10.1073/pnas.1307478110. Epub 2013 May 29.

PMID:
23720309
[PubMed - indexed for MEDLINE]
Free PMC Article

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