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Results: 1 to 20 of 333


Genital inflammation and the risk of HIV acquisition in women.

Masson L, Passmore JA, Liebenberg LJ, Werner L, Baxter C, Arnold KB, Williamson C, Little F, Mansoor LE, Naranbhai V, Lauffenburger DA, Ronacher K, Walzl G, Garrett NJ, Williams BL, Couto-Rodriguez M, Hornig M, Lipkin WI, Grobler A, Karim QA, Karim SS.

Clin Infect Dis. 2015 Apr 21. pii: civ298. [Epub ahead of print]


Differential levels of soluble inflammatory markers by human immunodeficiency virus controller status and demographics.

Li JZ, Arnold KB, Lo J, Dugast AS, Plants J, Ribaudo HJ, Cesa K, Heisey A, Kuritzkes DR, Lauffenburger DA, Alter G, Landay A, Grinspoon S, Pereyra F.

Open Forum Infect Dis. 2015 Jan 13;2(1):ofu117. doi: 10.1093/ofid/ofu117. eCollection 2015 Jan.


High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.

Wu L, Claas AM, Sarkar A, Lauffenburger DA, Han J.

Integr Biol (Camb). 2015 Apr 2. [Epub ahead of print]


ADAM8 as a drug target in pancreatic cancer.

Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW.

Nat Commun. 2015 Jan 28;6:6175. doi: 10.1038/ncomms7175.


Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.

Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH.

Lab Chip. 2015 Feb 21;15(4):1153-9. doi: 10.1039/c4lc01162g.


Innovation and insight in integrative biology.

Lauffenburger DA.

Integr Biol (Camb). 2015 Jan;7(1):9. doi: 10.1039/c4ib90047b. No abstract available.


Prioritisation and network analysis of Crohn's disease susceptibility genes.

Muraro D, Lauffenburger DA, Simmons A.

PLoS One. 2014 Sep 30;9(9):e108624. doi: 10.1371/journal.pone.0108624. eCollection 2014.


Reply to Azuaje: Predicting effective combined therapies for heterogeneous tumors.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4288. doi: 10.1073/pnas.1415737111. Epub 2014 Sep 24. No abstract available.


Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.

Tape CJ, Worboys JD, Sinclair J, Gourlay R, Vogt J, McMahon KM, Trost M, Lauffenburger DA, Lamont DJ, Jørgensen C.

Anal Chem. 2014 Oct 21;86(20):10296-302. doi: 10.1021/ac5025842. Epub 2014 Oct 2.


Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.

Palmer CD, Tomassilli J, Sirignano M, Romero-Tejeda M, Arnold KB, Che D, Lauffenburger DA, Jost S, Allen T, Mayer KH, Altfeld M.

AIDS. 2014 Sep 10;28(14):2162-6.


Intratumor heterogeneity alters most effective drugs in designed combinations.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10773-8. doi: 10.1073/pnas.1323934111. Epub 2014 Jul 7.


A microphysiological system model of therapy for liver micrometastases.

Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A.

Exp Biol Med (Maywood). 2014 Sep;239(9):1170-9. doi: 10.1177/1535370214532596. Epub 2014 May 12. Review.


Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture.

Tape CJ, Norrie IC, Worboys JD, Lim L, Lauffenburger DA, Jørgensen C.

Mol Cell Proteomics. 2014 Jul;13(7):1866-76. doi: 10.1074/mcp.O113.037119. Epub 2014 May 12.


Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.

Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT.

Drug Discov Today. 2014 Jun;19(6):754-62. doi: 10.1016/j.drudis.2014.04.017. Epub 2014 May 2. Review.


Microfluidic probe for single-cell analysis in adherent tissue culture.

Sarkar A, Kolitz S, Lauffenburger DA, Han J.

Nat Commun. 2014 Mar 5;5:3421. doi: 10.1038/ncomms4421.


Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.

Beste MT, Pfäffle-Doyle N, Prentice EA, Morris SN, Lauffenburger DA, Isaacson KB, Griffith LG.

Sci Transl Med. 2014 Feb 5;6(222):222ra16. doi: 10.1126/scitranslmed.3007988.


Addressing genetic tumor heterogeneity through computationally predictive combination therapy.

Zhao B, Pritchard JR, Lauffenburger DA, Hemann MT.

Cancer Discov. 2014 Feb;4(2):166-74. doi: 10.1158/2159-8290.CD-13-0465. Epub 2013 Dec 6.


Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.

Arneja A, Johnson H, Gabrovsek L, Lauffenburger DA, White FM.

J Immunol. 2014 Jan 1;192(1):123-35. doi: 10.4049/jimmunol.1302291. Epub 2013 Dec 2.


Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data.

Melas IN, Lauffenburger DA, Alexopoulos LG.

Proc IEEE Int Symp Bioinformatics Bioeng. 2013 Nov;2013. pii: 14026468.


HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways.

Simmons RP, Scully EP, Groden EE, Arnold KB, Chang JJ, Lane K, Lifson J, Rosenberg E, Lauffenburger DA, Altfeld M.

AIDS. 2013 Oct 23;27(16):2505-17. doi: 10.1097/01.aids.0000432455.06476.bc.

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