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Results: 1 to 20 of 324

1.

Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.

Palmer CD, Tomassilli J, Sirignano M, Tejeda MR, Arnold KB, Che D, Lauffenburger DA, Jost S, Allen T, Mayer KH, Altfeld M.

AIDS. 2014 Jul 4. [Epub ahead of print]

PMID:
25003719
[PubMed - as supplied by publisher]
2.

Intratumor heterogeneity alters most effective drugs in designed combinations.

Zhao B, Hemann MT, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10773-8. doi: 10.1073/pnas.1323934111. Epub 2014 Jul 7.

PMID:
25002493
[PubMed - in process]
Free Article
3.

A microphysiological system model of therapy for liver micrometastases.

Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A.

Exp Biol Med (Maywood). 2014 May 12. [Epub ahead of print]

PMID:
24821820
[PubMed - as supplied by publisher]
4.

Cell-specific Labeling Enzymes for Analysis of Cell-Cell Communication in Continuous Co-culture.

Tape CJ, Norrie IC, Worboys JD, Lim L, Lauffenburger DA, Jørgensen C.

Mol Cell Proteomics. 2014 Jul;13(7):1866-76. doi: 10.1074/mcp.O113.037119. Epub 2014 May 12.

PMID:
24820872
[PubMed - in process]
5.

Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.

Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT.

Drug Discov Today. 2014 Jun;19(6):754-62. doi: 10.1016/j.drudis.2014.04.017. Epub 2014 May 2.

PMID:
24793141
[PubMed - in process]
6.

Microfluidic probe for single-cell analysis in adherent tissue culture.

Sarkar A, Kolitz S, Lauffenburger DA, Han J.

Nat Commun. 2014 Mar 5;5:3421. doi: 10.1038/ncomms4421.

PMID:
24594667
[PubMed - in process]
7.

Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.

Beste MT, Pfäffle-Doyle N, Prentice EA, Morris SN, Lauffenburger DA, Isaacson KB, Griffith LG.

Sci Transl Med. 2014 Feb 5;6(222):222ra16. doi: 10.1126/scitranslmed.3007988.

PMID:
24500404
[PubMed - in process]
8.

Addressing genetic tumor heterogeneity through computationally predictive combination therapy.

Zhao B, Pritchard JR, Lauffenburger DA, Hemann MT.

Cancer Discov. 2014 Feb;4(2):166-74. doi: 10.1158/2159-8290.CD-13-0465. Epub 2013 Dec 6.

PMID:
24318931
[PubMed - in process]
Free PMC Article
9.

Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.

Arneja A, Johnson H, Gabrovsek L, Lauffenburger DA, White FM.

J Immunol. 2014 Jan 1;192(1):123-35. doi: 10.4049/jimmunol.1302291. Epub 2013 Dec 2.

PMID:
24298013
[PubMed - indexed for MEDLINE]
10.

Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data.

Melas IN, Lauffenburger DA, Alexopoulos LG.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:2680-3. doi: 10.1109/EMBC.2013.6610092.

PMID:
24110279
[PubMed - in process]
11.

HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways.

Simmons RP, Scully EP, Groden EE, Arnold KB, Chang JJ, Lane K, Lifson J, Rosenberg E, Lauffenburger DA, Altfeld M.

AIDS. 2013 Oct 23;27(16):2505-17. doi: 10.1097/01.aids.0000432455.06476.bc.

PMID:
24096630
[PubMed - indexed for MEDLINE]
12.

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM.

Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2.

PMID:
24084984
[PubMed - indexed for MEDLINE]
13.

Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context.

Hang TC, Tedford NC, Reddy RJ, Rimchala T, Wells A, White FM, Kamm RD, Lauffenburger DA.

Mol Cell Proteomics. 2013 Dec;12(12):3704-18. doi: 10.1074/mcp.M113.030528. Epub 2013 Sep 9.

PMID:
24023389
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells.

Meyer AS, Miller MA, Gertler FB, Lauffenburger DA.

Sci Signal. 2013 Aug 6;6(287):ra66. doi: 10.1126/scisignal.2004155.

PMID:
23921085
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.

Wagner JP, Wolf-Yadlin A, Sevecka M, Grenier JK, Root DE, Lauffenburger DA, MacBeath G.

Sci Signal. 2013 Jul 16;6(284):ra58. doi: 10.1126/scisignal.2003994.

PMID:
23861540
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrated network analyses for functional genomic studies in cancer.

Wilson JL, Hemann MT, Fraenkel E, Lauffenburger DA.

Semin Cancer Biol. 2013 Aug;23(4):213-8. doi: 10.1016/j.semcancer.2013.06.004. Epub 2013 Jun 27. Review.

PMID:
23811269
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Models of signalling networks - what cell biologists can gain from them and give to them.

Janes KA, Lauffenburger DA.

J Cell Sci. 2013 May 1;126(Pt 9):1913-21. doi: 10.1242/jcs.112045. Review.

PMID:
23720376
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.

Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9776-81. doi: 10.1073/pnas.1307478110. Epub 2013 May 29.

PMID:
23720309
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice.

Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, Saghatelian A, White FM.

Integr Biol (Camb). 2013 Jul 24;5(7):940-63. doi: 10.1039/c3ib40013a. Epub 2013 May 20.

PMID:
23685806
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.

Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):E2074-83. doi: 10.1073/pnas.1222387110. Epub 2013 May 14.

PMID:
23674691
[PubMed - indexed for MEDLINE]
Free PMC Article

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