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Results: 1 to 20 of 52

1.

Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes.

Langley RJ, Tipper JL, Bruse S, Baron RM, Tsalik EL, Huntley J, Rogers AJ, Jaramillo RJ, O'Donnell D, Mega WM, Keaton M, Kensicki E, Gazourian L, Fredenburgh LE, Massaro AF, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF, Sopori ML, Perrella MA, Choi AM, Harrod KS.

Am J Respir Crit Care Med. 2014 Aug 15;190(4):445-55. doi: 10.1164/rccm.201404-0624OC.

PMID:
25054455
[PubMed - in process]
2.

Metabolomic derangements are associated with mortality in critically ill adult patients.

Rogers AJ, McGeachie M, Baron RM, Gazourian L, Haspel JA, Nakahira K, Fredenburgh LE, Hunninghake GM, Raby BA, Matthay MA, Otero RM, Fowler VG, Rivers EP, Woods CW, Kingsmore S, Langley RJ, Choi AM.

PLoS One. 2014 Jan 30;9(1):e87538. doi: 10.1371/journal.pone.0087538. eCollection 2014.

PMID:
24498130
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors.

Gundavarapu S, Mishra NC, Singh SP, Langley RJ, Saeed AI, Feghali-Bostwick CA, McIntosh JM, Hutt J, Hegde R, Buch S, Sopori ML.

PLoS One. 2013 Oct 14;8(10):e77160. doi: 10.1371/journal.pone.0077160. eCollection 2013.

PMID:
24155926
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

An integrated clinico-metabolomic model improves prediction of death in sepsis.

Langley RJ, Tsalik EL, van Velkinburgh JC, Glickman SW, Rice BJ, Wang C, Chen B, Carin L, Suarez A, Mohney RP, Freeman DH, Wang M, You J, Wulff J, Thompson JW, Moseley MA, Reisinger S, Edmonds BT, Grinnell B, Nelson DR, Dinwiddie DL, Miller NA, Saunders CJ, Soden SS, Rogers AJ, Gazourian L, Fredenburgh LE, Massaro AF, Baron RM, Choi AM, Corey GR, Ginsburg GS, Cairns CB, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF.

Sci Transl Med. 2013 Jul 24;5(195):195ra95. doi: 10.1126/scitranslmed.3005893.

PMID:
23884467
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Gestational exposure of mice to secondhand cigarette smoke causes bronchopulmonary dysplasia blocked by the nicotinic receptor antagonist mecamylamine.

Singh SP, Gundavarapu S, Smith KR, Chand HS, Saeed AI, Mishra NC, Hutt J, Barrett EG, Husain M, Harrod KS, Langley RJ, Sopori ML.

Environ Health Perspect. 2013 Aug;121(8):957-64. doi: 10.1289/ehp.1306611. Epub 2013 Jun 7.

PMID:
23757602
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans.

Ahn SH, Tsalik EL, Cyr DD, Zhang Y, van Velkinburgh JC, Langley RJ, Glickman SW, Cairns CB, Zaas AK, Rivers EP, Otero RM, Veldman T, Kingsmore SF, Lucas J, Woods CW, Ginsburg GS, Fowler VG Jr.

PLoS One. 2013;8(1):e48979. doi: 10.1371/journal.pone.0048979. Epub 2013 Jan 9.

PMID:
23326304
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structural and functional properties of staphylococcal superantigen-like protein 4.

Hermans SJ, Baker HM, Sequeira RP, Langley RJ, Baker EN, Fraser JD.

Infect Immun. 2012 Nov;80(11):4004-13. doi: 10.1128/IAI.00764-12. Epub 2012 Sep 4.

PMID:
22949551
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3.

Deng L, Langley RJ, Wang Q, Topalian SL, Mariuzza RA.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14960-5. doi: 10.1073/pnas.1207186109. Epub 2012 Aug 28.

PMID:
22930819
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.

Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Peña-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML.

J Allergy Clin Immunol. 2012 Sep;130(3):770-780.e11. doi: 10.1016/j.jaci.2012.04.002. Epub 2012 May 9.

PMID:
22578901
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Inhalation of sulfur mustard causes long-term T cell-dependent inflammation: possible role of Th17 cells in chronic lung pathology.

Mishra NC, Rir-sima-ah J, Grotendorst GR, Langley RJ, Singh SP, Gundavarapu S, Weber WM, Pena-Philippides JC, Duncan MR, Sopori ML.

Int Immunopharmacol. 2012 May;13(1):101-8. doi: 10.1016/j.intimp.2012.03.010. Epub 2012 Mar 28.

PMID:
22465472
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Discriminative value of inflammatory biomarkers for suspected sepsis.

Tsalik EL, Jaggers LB, Glickman SW, Langley RJ, van Velkinburgh JC, Park LP, Fowler VG, Cairns CB, Kingsmore SF, Woods CW.

J Emerg Med. 2012 Jul;43(1):97-106. doi: 10.1016/j.jemermed.2011.05.072. Epub 2011 Nov 6.

PMID:
22056545
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Prenatal secondhand cigarette smoke promotes Th2 polarization and impairs goblet cell differentiation and airway mucus formation.

Singh SP, Gundavarapu S, Peña-Philippides JC, Rir-Sima-ah J, Mishra NC, Wilder JA, Langley RJ, Smith KR, Sopori ML.

J Immunol. 2011 Nov 1;187(9):4542-52. doi: 10.4049/jimmunol.1101567. Epub 2011 Sep 19.

PMID:
21930963
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Fibrogenic and redox-related but not proinflammatory genes are upregulated in Lewis rat model of chronic silicosis.

Langley RJ, Mishra NC, Peña-Philippides JC, Rice BJ, Seagrave JC, Singh SP, Sopori ML.

J Toxicol Environ Health A. 2011;74(19):1261-79. doi: 10.1080/15287394.2011.595669.

PMID:
21830856
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The role of IL-1β in nicotine-induced immunosuppression and neuroimmune communication.

Razani-Boroujerdi S, Langley RJ, Singh SP, Pena-Philippides JC, Rir-sima-ah J, Gundavarapu S, Mishra NC, Sopori ML.

J Neuroimmune Pharmacol. 2011 Dec;6(4):585-96. doi: 10.1007/s11481-011-9284-5. Epub 2011 Jun 14.

PMID:
21671006
[PubMed - indexed for MEDLINE]
15.

Carrier testing for severe childhood recessive diseases by next-generation sequencing.

Bell CJ, Dinwiddie DL, Miller NA, Hateley SL, Ganusova EE, Mudge J, Langley RJ, Zhang L, Lee CC, Schilkey FD, Sheth V, Woodward JE, Peckham HE, Schroth GP, Kim RW, Kingsmore SF.

Sci Transl Med. 2011 Jan 12;3(65):65ra4. doi: 10.1126/scitranslmed.3001756.

PMID:
21228398
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes.

Chen C, Farmer AD, Langley RJ, Mudge J, Crow JA, May GD, Huntley J, Smith AG, Retzel EF.

BMC Plant Biol. 2010 Dec 17;10:280. doi: 10.1186/1471-2229-10-280.

PMID:
21167045
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Nicotine inhibits Fc epsilon RI-induced cysteinyl leukotrienes and cytokine production without affecting mast cell degranulation through alpha 7/alpha 9/alpha 10-nicotinic receptors.

Mishra NC, Rir-sima-ah J, Boyd RT, Singh SP, Gundavarapu S, Langley RJ, Razani-Boroujerdi S, Sopori ML.

J Immunol. 2010 Jul 1;185(1):588-96. doi: 10.4049/jimmunol.0902227. Epub 2010 May 26.

PMID:
20505147
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Specificity of staphylococcal superantigen-like protein 10 toward the human IgG1 Fc domain.

Patel D, Wines BD, Langley RJ, Fraser JD.

J Immunol. 2010 Jun 1;184(11):6283-92. doi: 10.4049/jimmunol.0903311. Epub 2010 Apr 28.

PMID:
20427768
[PubMed - indexed for MEDLINE]
Free Article
19.

An integrated transcriptome atlas of the crop model Glycine max, and its use in comparative analyses in plants.

Libault M, Farmer A, Joshi T, Takahashi K, Langley RJ, Franklin LD, He J, Xu D, May G, Stacey G.

Plant J. 2010 Jul 1;63(1):86-99. doi: 10.1111/j.1365-313X.2010.04222.x. Epub 2010 Apr 7.

PMID:
20408999
[PubMed - indexed for MEDLINE]
20.

Granuloma formation induced by low-dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats.

Langley RJ, Mishra NC, Peña-Philippides JC, Hutt JA, Sopori ML.

J Toxicol Environ Health A. 2010;73(10):669-83. doi: 10.1080/15287390903578521.

PMID:
20391111
[PubMed - indexed for MEDLINE]
Free PMC Article

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