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Results: 1 to 20 of 146

1.

Stable Isotope-Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS.

Higashi RM, Fan TW, Lorkiewicz PK, Moseley HN, Lane AN.

Methods Mol Biol. 2014;1198:147-67. doi: 10.1007/978-1-4939-1258-2_11.

PMID:
25270929
[PubMed - in process]
2.

Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics.

Mitchell JM, Fan TW, Lane AN, Moseley HN.

Front Genet. 2014 Jul 28;5:237. doi: 10.3389/fgene.2014.00237. eCollection 2014.

PMID:
25120557
[PubMed]
Free PMC Article
3.

Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth.

Chesney J, Clark J, Klarer AC, Imbert-Fernandez Y, Lane AN, Telang S.

Oncotarget. 2014 Aug 30;5(16):6670-86.

PMID:
25115398
[PubMed - in process]
Free PMC Article
4.

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.

Ren JG, Seth P, Clish CB, Lorkiewicz PK, Higashi RM, Lane AN, Fan TW, Sukhatme VP.

Sci Rep. 2014 Jun 24;4:5414. doi: 10.1038/srep05414.

PMID:
24957098
[PubMed - in process]
Free PMC Article
5.

Structural insights into the evolution of a sexy protein: novel topology and restricted backbone flexibility in a hypervariable pheromone from the red-legged salamander, Plethodon shermani.

Wilburn DB, Bowen KE, Doty KA, Arumugam S, Lane AN, Feldhoff PW, Feldhoff RC.

PLoS One. 2014 May 21;9(5):e96975. doi: 10.1371/journal.pone.0096975. eCollection 2014.

PMID:
24849290
[PubMed - in process]
Free PMC Article
6.

Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.

Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M 2nd, Lane AN, Higashi RM, Fan TW, Pandolfi PP, Sukhatme VP, Seth P.

Cell Metab. 2014 May 6;19(5):795-809. doi: 10.1016/j.cmet.2014.03.003. Epub 2014 Apr 10.

PMID:
24726384
[PubMed - in process]
7.

Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.

Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, Fan TW, Theodorescu D.

J Natl Cancer Inst. 2014 Apr 3;106(5). pii: dju062. doi: 10.1093/jnci/dju062.

PMID:
24700805
[PubMed - indexed for MEDLINE]
8.

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma.

Yang Y, Lane AN, Ricketts CJ, Sourbier C, Wei MH, Shuch B, Pike L, Wu M, Rouault TA, Boros LG, Fan TW, Linehan WM.

PLoS One. 2013 Aug 15;8(8):e72179. doi: 10.1371/journal.pone.0072179. eCollection 2013.

PMID:
23967283
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.

Buscaglia R, Miller MC, Dean WL, Gray RD, Lane AN, Trent JO, Chaires JB.

Nucleic Acids Res. 2013 Sep;41(16):7934-46. doi: 10.1093/nar/gkt440. Epub 2013 Jun 26.

PMID:
23804761
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Control of glutamine metabolism by the tumor suppressor Rb.

Reynolds MR, Lane AN, Robertson B, Kemp S, Liu Y, Hill BG, Dean DC, Clem BF.

Oncogene. 2014 Jan 30;33(5):556-66. doi: 10.1038/onc.2012.635. Epub 2013 Jan 28.

PMID:
23353822
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.

Lorkiewicz P, Higashi RM, Lane AN, Fan TW.

Metabolomics. 2012;8(5):930-939. Epub 2011 Dec 9.

PMID:
23101002
[PubMed]
Free PMC Article
12.

Administration of exogenous adenosine triphosphate to ischemic skeletal muscle induces an energy-sparing effect: role of adenosine receptors.

Maldonado C, Pushpakumar SB, Perez-Abadia G, Arumugam S, Lane AN.

J Surg Res. 2013 May 1;181(1):e15-22. doi: 10.1016/j.jss.2012.06.033. Epub 2012 Jul 6.

PMID:
22795271
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.

Liu W, Le A, Hancock C, Lane AN, Dang CV, Fan TW, Phang JM.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8983-8. doi: 10.1073/pnas.1203244109. Epub 2012 May 21.

PMID:
22615405
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.

Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, Zhang H, Zimmerman LJ, Liebler DC, Slebos RJ, Lorkiewicz PK, Higashi RM, Fan TW, Dang CV.

Cell Metab. 2012 Jan 4;15(1):110-21. doi: 10.1016/j.cmet.2011.12.009.

PMID:
22225880
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Stable isotope-resolved metabolomics and applications for drug development.

Fan TW, Lorkiewicz PK, Sellers K, Moseley HN, Higashi RM, Lane AN.

Pharmacol Ther. 2012 Mar;133(3):366-91. doi: 10.1016/j.pharmthera.2011.12.007. Epub 2011 Dec 23. Review.

PMID:
22212615
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Scaled-up separation of cellobiohydrolase1 from a cellulase mixture by ion-exchange chromatography.

Ye Z, Lane AN, Willing GA, Berson RE.

Biotechnol Prog. 2011 Nov-Dec;27(6):1644-52. doi: 10.1002/btpr.696. Epub 2011 Sep 8.

PMID:
21905272
[PubMed - indexed for MEDLINE]
17.

The stability of intramolecular DNA G-quadruplexes compared with other macromolecules.

Lane AN.

Biochimie. 2012 Feb;94(2):277-86. doi: 10.1016/j.biochi.2011.08.004. Epub 2011 Aug 11. Review.

PMID:
21854828
[PubMed - indexed for MEDLINE]
18.

Stable isotope resolved metabolomics of lung cancer in a SCID mouse model.

Fan TW, Lane AN, Higashi RM, Yan J.

Metabolomics. 2011 Jun 1;7(2):257-269.

PMID:
21666826
[PubMed]
Free PMC Article
19.

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions.

Moseley HN, Lane AN, Belshoff AC, Higashi RM, Fan TW.

BMC Biol. 2011 May 31;9:37. doi: 10.1186/1741-7007-9-37.

PMID:
21627825
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

NMR-based stable isotope resolved metabolomics in systems biochemistry.

Fan TW, Lane AN.

J Biomol NMR. 2011 Apr;49(3-4):267-80. doi: 10.1007/s10858-011-9484-6. Epub 2011 Feb 26. Erratum in: J Biomol NMR. 2011 Apr;49(3-4):325.

PMID:
21350847
[PubMed - indexed for MEDLINE]
Free PMC Article

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