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Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: abstracts from the 2014 Scientific and Educational Symposium.

Kline AD, Calof AL, Lander AD, Gerton JL, Krantz ID, Dorsett D, Deardorff MA, Blagowidow N, Yokomori K, Shirahige K, Santos R, Woodman J, Megee PC, O'Connor JT, Egense A, Noon S, Belote M, Goodban MT, Hansen BD, Timmons JG, Musio A, Ishman SL, Bryan Y, Wu Y, Bettini LR, Mehta D, Zakari M, Mills JA, Srivastava S, Haaland RE.

Am J Med Genet A. 2015 Jun;167(6):1179-92. doi: 10.1002/ajmg.a.37056. Epub 2015 Apr 21.


Organ-level quorum sensing directs regeneration in hair stem cell populations.

Chen CC, Wang L, Plikus MV, Jiang TX, Murray PJ, Ramos R, Guerrero-Juarez CF, Hughes MW, Lee OK, Shi S, Widelitz RB, Lander AD, Chuong CM.

Cell. 2015 Apr 9;161(2):277-90. doi: 10.1016/j.cell.2015.02.016.


Cell lineage branching as a strategy for proliferative control.

Buzi G, Lander AD, Khammash M.

BMC Biol. 2015 Feb 19;13:13. doi: 10.1186/s12915-015-0122-8.


Robust and precise morphogen-mediated patterning: trade-offs, constraints and mechanisms.

Lo WC, Zhou S, Wan FY, Lander AD, Nie Q.

J R Soc Interface. 2015 Jan 6;12(102):20141041.


Nipbl and mediator cooperatively regulate gene expression to control limb development.

Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF.

PLoS Genet. 2014 Sep 25;10(9):e1004671. doi: 10.1371/journal.pgen.1004671. eCollection 2014 Sep.


Making sense in biology: an appreciation of Julian Lewis.

Lander AD.

BMC Biol. 2014 Aug 2;12:57. doi: 10.1186/s12915-014-0057-5. No abstract available.


The protective role of symmetric stem cell division on the accumulation of heritable damage.

McHale PT, Lander AD.

PLoS Comput Biol. 2014 Aug 14;10(8):e1003802. doi: 10.1371/journal.pcbi.1003802. eCollection 2014 Aug.


Predicting mechanism of biphasic growth factor action on tumor growth using a multi-species model with feedback control.

Konstorum A, Sprowl SA, Waterman ML, Lander AD, Lowengrub JS.

J Coupled Syst Multiscale Dyn. 2013 Dec 1;1(4):459-467.


A BMP-FGF morphogen toggle switch drives the ultrasensitive expression of multiple genes in the developing forebrain.

Srinivasan S, Hu JS, Currle DS, Fung ES, Hayes WB, Lander AD, Monuki ES.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003463. doi: 10.1371/journal.pcbi.1003463. eCollection 2014 Feb.


Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I.

Visnes T, Giordano F, Kuznetsova A, Suja JA, Lander AD, Calof AL, Ström L.

Chromosoma. 2014 Jun;123(3):239-52. doi: 10.1007/s00412-013-0444-7. Epub 2013 Nov 28.


Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

Remeseiro S, Cuadrado A, Kawauchi S, Calof AL, Lander AD, Losada A.

Biochim Biophys Acta. 2013 Dec;1832(12):2097-102. doi: 10.1016/j.bbadis.2013.07.020. Epub 2013 Aug 3.


How cells know where they are.

Lander AD.

Science. 2013 Feb 22;339(6122):923-7. doi: 10.1126/science.1224186. Review.


Dynamics and precision in retinoic acid morphogen gradients.

Schilling TF, Nie Q, Lander AD.

Curr Opin Genet Dev. 2012 Dec;22(6):562-9. doi: 10.1016/j.gde.2012.11.012. Epub 2012 Dec 19. Review.


The genetics of alcohol dependence: advancing towards systems-based approaches.

Palmer RH, McGeary JE, Francazio S, Raphael BJ, Lander AD, Heath AC, Knopik VS.

Drug Alcohol Depend. 2012 Oct 1;125(3):179-91. doi: 10.1016/j.drugalcdep.2012.07.005. Epub 2012 Jul 31. Review.


Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish.

Cai AQ, Radtke K, Linville A, Lander AD, Nie Q, Schilling TF.

Development. 2012 Jun;139(12):2150-5. doi: 10.1242/dev.077065.


Multispecies model of cell lineages and feedback control in solid tumors.

Youssefpour H, Li X, Lander AD, Lowengrub JS.

J Theor Biol. 2012 Jul 7;304:39-59. doi: 10.1016/j.jtbi.2012.02.030. Epub 2012 Mar 31.


Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster.

Kim MS, Kim JR, Kim D, Lander AD, Cho KH.

BMC Syst Biol. 2012 May 1;6:31. doi: 10.1186/1752-0509-6-31.


Free extracellular diffusion creates the Dpp morphogen gradient of the Drosophila wing disc.

Zhou S, Lo WC, Suhalim JL, Digman MA, Gratton E, Nie Q, Lander AD.

Curr Biol. 2012 Apr 24;22(8):668-75. doi: 10.1016/j.cub.2012.02.065. Epub 2012 Mar 22.


What does the concept of the stem cell niche really mean today?

Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T.

BMC Biol. 2012 Mar 9;10:19. doi: 10.1186/1741-7007-10-19. No abstract available.

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