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Results: 1 to 20 of 216

1.

Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer.

Martinez VD, Vucic EA, Thu KL, Pikor LA, Hubaux R, Lam WL.

Biomed Res Int. 2014;2014:159459. doi: 10.1155/2014/159459. Epub 2014 Jul 9.

PMID:
25114896
[PubMed - in process]
Free PMC Article
2.

Re: the Wnt signaling pathway in non-small cell lung cancer.

Hubaux R, Thu KL, Lam WL.

J Natl Cancer Inst. 2014 Jul 31;106(8). pii: dju188. doi: 10.1093/jnci/dju188. Print 2014 Aug. No abstract available.

PMID:
25082336
[PubMed - in process]
3.

A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets.

Taguchi A, Taylor AD, Rodriguez J, Celiktaş M, Liu H, Ma X, Zhang Q, Wong CH, Chin A, Girard L, Behrens C, Lam WL, Lam S, Minna JD, Wistuba II, Gazdar AF, Hanash SM.

Cancer Res. 2014 Jun 26. [Epub ahead of print]

PMID:
24970476
[PubMed - as supplied by publisher]
4.

Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.

Martinez VD, Vucic EA, Thu KL, Pikor LA, Lam S, Lam WL.

Head Neck. 2014 Mar 5. doi: 10.1002/hed.23663. [Epub ahead of print]

PMID:
24596130
[PubMed - as supplied by publisher]
5.

Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.

Olthof NC, Speel EJ, Kolligs J, Haesevoets A, Henfling M, Ramaekers FC, Preuss SF, Drebber U, Wieland U, Silling S, Lam WL, Vucic EA, Kremer B, Klussmann JP, Huebbers CU.

PLoS One. 2014 Feb 24;9(2):e88718. doi: 10.1371/journal.pone.0088718. eCollection 2014.

PMID:
24586376
[PubMed - in process]
Free PMC Article
6.

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer.

Crea F, Watahiki A, Quagliata L, Xue H, Pikor L, Parolia A, Wang Y, Lin D, Lam WL, Farrar WL, Isogai T, Morant R, Castori-Eppenberger S, Chi KN, Wang Y, Helgason CD.

Oncotarget. 2014 Feb 15;5(3):764-74.

PMID:
24519926
[PubMed - in process]
Free PMC Article
7.

Sarcomatoid carcinoma in head and neck: a review of 30 years of experience--clinical outcomes and reconstructive results.

Chang NJ, Kao DS, Lee LY, Chang JW, Hou MM, Lam WL, Cheng MH.

Ann Plast Surg. 2013 Dec;71 Suppl 1:S1-7. doi: 10.1097/SAP.0000000000000069.

PMID:
24284734
[PubMed - in process]
8.

DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways.

Vucic EA, Chari R, Thu KL, Wilson IM, Cotton AM, Kennett JY, Zhang M, Lonergan KM, Steiling K, Brown CJ, McWilliams A, Ohtani K, Lenburg ME, Sin DD, Spira A, Macaulay CE, Lam S, Lam WL.

Am J Respir Cell Mol Biol. 2014 May;50(5):912-22. doi: 10.1165/rcmb.2013-0304OC.

PMID:
24298892
[PubMed - indexed for MEDLINE]
9.

Emerging arsenic threat in Canada.

Martinez VD, Vucic EA, Lam S, Lam WL.

Science. 2013 Nov 1;342(6158):559. doi: 10.1126/science.342.6158.559-a. No abstract available.

PMID:
24179203
[PubMed - indexed for MEDLINE]
10.

YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway.

Pikor LA, Lockwood WW, Thu KL, Vucic EA, Chari R, Gazdar AF, Lam S, Lam WL.

Cancer Res. 2013 Dec 15;73(24):7301-12. doi: 10.1158/0008-5472.CAN-13-1897. Epub 2013 Oct 29.

PMID:
24170126
[PubMed - indexed for MEDLINE]
11.

Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.

Martinez VD, Vucic EA, Pikor LA, Thu KL, Hubaux R, Lam WL.

Mol Cancer. 2013 Oct 20;12(1):124. doi: 10.1186/1476-4598-12-124.

PMID:
24138990
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

In response.

Hubaux R, Thu KL, Lam WL, Alex A.

J Thorac Oncol. 2013 Nov;8(11):e103-4. doi: 10.1097/01.JTO.0000435739.64803.99. No abstract available.

PMID:
24128723
[PubMed - indexed for MEDLINE]
13.

Whole-genome sequencing analysis identifies a distinctive mutational spectrum in an arsenic-related lung tumor.

Martinez VD, Thu KL, Vucic EA, Hubaux R, Adonis M, Gil L, MacAulay C, Lam S, Lam WL.

J Thorac Oncol. 2013 Nov;8(11):1451-5. doi: 10.1097/JTO.0b013e3182a4dd8e.

PMID:
24128716
[PubMed - indexed for MEDLINE]
14.

EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.

Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, Macaulay CE, Karsan A, Gazdar AF, Lam S, Lam WL.

Oncogene. 2013 Oct 7. doi: 10.1038/onc.2013.396. [Epub ahead of print]

PMID:
24096489
[PubMed - as supplied by publisher]
15.

CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer.

Tam KW, Zhang W, Soh J, Stastny V, Chen M, Sun H, Thu K, Rios JJ, Yang C, Marconett CN, Selamat SA, Laird-Offringa IA, Taguchi A, Hanash S, Shames D, Ma X, Zhang MQ, Lam WL, Gazdar A.

J Thorac Oncol. 2013 Nov;8(11):1378-88. doi: 10.1097/JTO.0b013e3182a46c0c.

PMID:
24077454
[PubMed - indexed for MEDLINE]
16.

Genetic alterations defining NSCLC subtypes and their therapeutic implications.

Pikor LA, Ramnarine VR, Lam S, Lam WL.

Lung Cancer. 2013 Nov;82(2):179-89. doi: 10.1016/j.lungcan.2013.07.025. Epub 2013 Aug 20. Review.

PMID:
24011633
[PubMed - indexed for MEDLINE]
Free Article
17.

Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer.

Coe BP, Thu KL, Aviel-Ronen S, Vucic EA, Gazdar AF, Lam S, Tsao MS, Lam WL.

PLoS One. 2013 Aug 15;8(8):e71670. doi: 10.1371/journal.pone.0071670. eCollection 2013.

PMID:
23967231
[PubMed - in process]
Free PMC Article
18.

Mutational analysis of Polycomb genes in solid tumours identifies PHC3 amplification as a possible cancer-driving genetic alteration.

Crea F, Sun L, Pikor L, Frumento P, Lam WL, Helgason CD.

Br J Cancer. 2013 Sep 17;109(6):1699-702. doi: 10.1038/bjc.2013.454. Epub 2013 Aug 13.

PMID:
23942079
[PubMed - indexed for MEDLINE]
19.

Improving the extensor lag and range of motion following free vascularized joint transfer to the proximal interphalangeal joint: Part 2. A clinical series.

Lam WL, Waughlock N, Hsu CC, Lin YT, Wei FC.

Plast Reconstr Surg. 2013 Aug;132(2):271e-280e. doi: 10.1097/PRS.0b013e31829589db.

PMID:
23897355
[PubMed - indexed for MEDLINE]
20.

Improving the extensor lag and range of motion following free vascularized joint transfer to the proximal interphalangeal joint: Part 1. An observational and cadaveric study.

Waughlock N, Hsu CC, Lam WL, Lin YT, Wei FC.

Plast Reconstr Surg. 2013 Aug;132(2):263e-270e. doi: 10.1097/PRS.0b013e31829589bd.

PMID:
23897354
[PubMed - indexed for MEDLINE]

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