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Results: 1 to 20 of 74


Mir-17-92 regulates bone marrow homing of plasma cells and production of immunoglobulin G2c.

Xu S, Ou X, Huo J, Lim K, Huang Y, Chee S, Lam KP.

Nat Commun. 2015 Apr 17;6:6764. doi: 10.1038/ncomms7764.


Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

Lee KG, Kim SS, Kui L, Voon DC, Mauduit M, Bist P, Bi X, Pereira NA, Liu C, Sukumaran B, Rénia L, Ito Y, Lam KP.

Cell Rep. 2015 Feb 24;10(7):1055-65. doi: 10.1016/j.celrep.2015.01.039. Epub 2015 Feb 19.


Multiplexed Separations for Biomarker Discovery in Metabolomics: Elucidating Adaptive Responses to Exercise Training.

Kuehnbaum NL, Gillen JB, Kormendi A, Lam KP, DiBattista A, Gibala MJ, Britz-McKibbin P.

Electrophoresis. 2015 Jan 28. doi: 10.1002/elps.201400604. [Epub ahead of print]


Aberrant presentation of self-lipids by autoimmune B cells depletes peripheral iNKT cells.

Tan AH, Chong WP, Ng SW, Basri N, Xu S, Lam KP.

Cell Rep. 2014 Oct 9;9(1):24-31. doi: 10.1016/j.celrep.2014.08.043. Epub 2014 Sep 25.


Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands.

Ou X, Xu S, Li YF, Lam KP.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11431-6. doi: 10.1073/pnas.1400539111. Epub 2014 Jul 22.


Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool.

Li YF, Xu S, Ou X, Lam KP.

Nat Commun. 2014 Jun 30;5:4273. doi: 10.1038/ncomms5273.


Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.

Badoud F, Lam KP, DiBattista A, Perreault M, Zulyniak MA, Cattrysse B, Stephenson S, Britz-McKibbin P, Mutch DM.

J Proteome Res. 2014 Jul 3;13(7):3455-66. doi: 10.1021/pr500416v. Epub 2014 Jun 23.


DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.

Kim SS, Lee KG, Chin CS, Ng SK, Pereira NA, Xu S, Lam KP.

J Immunol. 2014 Jul 15;193(2):840-8. doi: 10.4049/jimmunol.1301601. Epub 2014 Jun 13.


Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.

Loh WP, Loo B, Zhou L, Zhang P, Lee DY, Yang Y, Lam KP.

Biotechnol J. 2014 Sep;9(9):1140-51. doi: 10.1002/biot.201400050. Epub 2014 Jun 23.


Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected].

Bounab Y, Hesse AM, Iannascoli B, Grieco L, Couté Y, Niarakis A, Roncagalli R, Lie E, Lam KP, Demangel C, Thieffry D, Garin J, Malissen B, Daëron M.

Mol Cell Proteomics. 2013 Oct;12(10):2874-89. doi: 10.1074/mcp.M112.025908. Epub 2013 Jul 2. Erratum in: Mol Cell Proteomics. 2013 Feb ;13(2):678.


Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vector.

Ng SK, Tan TR, Wang Y, Ng D, Goh LT, Bardor M, Wong VV, Lam KP.

PLoS One. 2012;7(12):e52785. doi: 10.1371/journal.pone.0052785. Epub 2012 Dec 26.


Fas apoptosis inhibitory molecule is upregulated by IGF-1 signaling and modulates Akt activation and IRF4 expression in multiple myeloma.

Huo J, Xu S, Lin B, Chng WJ, Lam KP.

Leukemia. 2013 Apr;27(5):1165-71. doi: 10.1038/leu.2012.326. Epub 2012 Nov 9.


Identification of HEXIM1 as a positive regulator of p53.

Lew QJ, Chia YL, Chu KL, Lam YT, Gurumurthy M, Xu S, Lam KP, Cheong N, Chao SH.

J Biol Chem. 2012 Oct 19;287(43):36443-54. doi: 10.1074/jbc.M112.374157. Epub 2012 Sep 4.


Comprehensive analysis of CD4+ T cells in the decision between tolerance and immunity in vivo reveals a pivotal role for ICOS.

Lischke T, Hegemann A, Gurka S, Vu Van D, Burmeister Y, Lam KP, Kershaw O, Mollenkopf HJ, Mages HW, Hutloff A, Kroczek RA.

J Immunol. 2012 Jul 1;189(1):234-44. doi: 10.4049/jimmunol.1102034. Epub 2012 Jun 1.


Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response.

Lee KG, Xu S, Kang ZH, Huo J, Huang M, Liu D, Takeuchi O, Akira S, Lam KP.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5791-6. doi: 10.1073/pnas.1119238109. Epub 2012 Mar 27.


Integrative analysis workflow for the structural and functional classification of C-type lectins.

Koh G, Low A, Poh D, Yao Y, Ng SK, Wong VV, Vagenende V, Lam KP, Lee DY.

BMC Bioinformatics. 2011 Dec 14;12 Suppl 14:S5. doi: 10.1186/1471-2105-12-S14-S5.


The RNase III enzyme Dicer is essential for germinal center B-cell formation.

Xu S, Guo K, Zeng Q, Huo J, Lam KP.

Blood. 2012 Jan 19;119(3):767-76. doi: 10.1182/blood-2011-05-355412. Epub 2011 Nov 23.


Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells.

Silva DG, Daley SR, Hogan J, Lee SK, Teh CE, Hu DY, Lam KP, Goodnow CC, Vinuesa CG.

Diabetes. 2011 Aug;60(8):2102-11. doi: 10.2337/db10-1344.

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