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Results: 1 to 20 of 57

1.

An upstream open reading frame is essential for feedback regulation of ascorbate biosynthesis in Arabidopsis.

Laing WA, Martínez-Sánchez M, Wright MA, Bulley SM, Brewster D, Dare AP, Rassam M, Wang D, Storey R, Macknight RC, Hellens RP.

Plant Cell. 2015 Mar;27(3):772-86. doi: 10.1105/tpc.114.133777. Epub 2015 Feb 27.

PMID:
25724639
2.

Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice.

Espley RV, Butts CA, Laing WA, Martell S, Smith H, McGhie TK, Zhang J, Paturi G, Hedderley D, Bovy A, Schouten HJ, Putterill J, Allan AC, Hellens RP.

J Nutr. 2014 Feb;144(2):146-54. doi: 10.3945/jn.113.182659. Epub 2013 Dec 18.

3.

Modulation of colonic inflammation in Mdr1a(-/-) mice by green tea polyphenols and their effects on the colon transcriptome and proteome.

Barnett MP, Cooney JM, Dommels YE, Nones K, Brewster DT, Park Z, Butts CA, McNabb WC, Laing WA, Roy NC.

J Nutr Biochem. 2013 Oct;24(10):1678-90. doi: 10.1016/j.jnutbio.2013.02.007. Epub 2013 May 2.

PMID:
23643524
4.

Post-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets.

Bermingham EN, Bassett SA, Young W, Roy NC, McNabb WC, Cooney JM, Brewster DT, Laing WA, Barnett MP.

BMC Med Genomics. 2013 Mar 5;6:7. doi: 10.1186/1755-8794-6-7.

5.

Unusual immuno-modulatory triterpene-caffeates in the skins of russeted varieties of apples and pears.

Andre CM, Larsen L, Burgess EJ, Jensen DJ, Cooney JM, Evers D, Zhang J, Perry NB, Laing WA.

J Agric Food Chem. 2013 Mar 20;61(11):2773-9. doi: 10.1021/jf305190e. Epub 2013 Mar 4.

PMID:
23418665
6.

Anti-inflammatory procyanidins and triterpenes in 109 apple varieties.

Andre CM, Greenwood JM, Walker EG, Rassam M, Sullivan M, Evers D, Perry NB, Laing WA.

J Agric Food Chem. 2012 Oct 24;60(42):10546-54. doi: 10.1021/jf302809k. Epub 2012 Oct 10.

PMID:
23013475
7.

Allelic variation in paralogs of GDP-L-galactose phosphorylase is a major determinant of vitamin C concentrations in apple fruit.

Mellidou I, Chagné D, Laing WA, Keulemans J, Davey MW.

Plant Physiol. 2012 Nov;160(3):1613-29. doi: 10.1104/pp.112.203786. Epub 2012 Sep 21.

8.

QTL and candidate gene mapping for polyphenolic composition in apple fruit.

Chagné D, Krieger C, Rassam M, Sullivan M, Fraser J, André C, Pindo M, Troggio M, Gardiner SE, Henry RA, Allan AC, McGhie TK, Laing WA.

BMC Plant Biol. 2012 Jan 23;12:12. doi: 10.1186/1471-2229-12-12.

9.

Effects of kiwifruit extracts on colonic gene and protein expression levels in IL-10 gene-deficient mice.

Edmunds SJ, Roy NC, Davy M, Cooney JM, Barnett MP, Zhu S, Park Z, Love DR, Laing WA.

Br J Nutr. 2012 Jul 14;108(1):113-29. doi: 10.1017/S0007114511005241. Epub 2011 Dec 9.

PMID:
22152591
10.

Enhancing ascorbate in fruits and tubers through over-expression of the L-galactose pathway gene GDP-L-galactose phosphorylase.

Bulley S, Wright M, Rommens C, Yan H, Rassam M, Lin-Wang K, Andre C, Brewster D, Karunairetnam S, Allan AC, Laing WA.

Plant Biotechnol J. 2012 May;10(4):390-7. doi: 10.1111/j.1467-7652.2011.00668.x. Epub 2011 Dec 1.

PMID:
22129455
11.

Proteomic analysis of colon tissue from interleukin-10 gene-deficient mice fed polyunsaturated Fatty acids with comparison to transcriptomic analysis.

Cooney JM, Barnett MP, Brewster D, Knoch B, McNabb WC, Laing WA, Roy NC.

J Proteome Res. 2012 Feb 3;11(2):1065-77. doi: 10.1021/pr200807p. Epub 2011 Dec 13.

PMID:
22106967
12.

Kiwifruit extracts inhibit cytokine production by lipopolysaccharide-activated macrophages, and intestinal epithelial cells isolated from IL10 gene deficient mice.

Edmunds SJ, Roy NC, Love DR, Laing WA.

Cell Immunol. 2011;270(1):70-9. doi: 10.1016/j.cellimm.2011.04.004. Epub 2011 Apr 23.

PMID:
21600571
13.

Ethylene-regulated (methylsulfanyl)alkanoate ester biosynthesis is likely to be modulated by precursor availability in Actinidia chinensis genotypes.

Günther CS, Heinemann K, Laing WA, Nicolau L, Marsh KB.

J Plant Physiol. 2011 May 1;168(7):629-38. doi: 10.1016/j.jplph.2010.10.001. Epub 2010 Nov 10.

PMID:
21071110
14.

Chronic inflammation, mutation and human disease.

Ferguson LR, Laing WA.

Mutat Res. 2010 Aug 7;690(1-2):1-2. doi: 10.1016/j.mrfmmm.2010.06.011. Epub 2010 Jun 23. No abstract available.

PMID:
20600166
15.

Solution structure of the squash aspartic acid proteinase inhibitor (SQAPI) and mutational analysis of pepsin inhibition.

Headey SJ, Macaskill UK, Wright MA, Claridge JK, Edwards PJ, Farley PC, Christeller JT, Laing WA, Pascal SM.

J Biol Chem. 2010 Aug 27;285(35):27019-25. doi: 10.1074/jbc.M110.137018. Epub 2010 Jun 9.

16.

Quantification of folate in fruits and vegetables: A fluorescence-based homogeneous assay.

Martin H, Comeskey D, Simpson RM, Laing WA, McGhie TK.

Anal Biochem. 2010 Jul 15;402(2):137-45. doi: 10.1016/j.ab.2010.03.032. Epub 2010 Mar 31.

PMID:
20361923
17.

Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.

Crowhurst RN, Gleave AP, MacRae EA, Ampomah-Dwamena C, Atkinson RG, Beuning LL, Bulley SM, Chagne D, Marsh KB, Matich AJ, Montefiori M, Newcomb RD, Schaffer RJ, Usadel B, Allan AC, Boldingh HL, Bowen JH, Davy MW, Eckloff R, Ferguson AR, Fraser LG, Gera E, Hellens RP, Janssen BJ, Klages K, Lo KR, MacDiarmid RM, Nain B, McNeilage MA, Rassam M, Richardson AC, Rikkerink EH, Ross GS, Schröder R, Snowden KC, Souleyre EJ, Templeton MD, Walton EF, Wang D, Wang MY, Wang YY, Wood M, Wu R, Yauk YK, Laing WA.

BMC Genomics. 2008 Jul 27;9:351. doi: 10.1186/1471-2164-9-351.

18.

MYB transcription factors that colour our fruit.

Allan AC, Hellens RP, Laing WA.

Trends Plant Sci. 2008 Mar;13(3):99-102. doi: 10.1016/j.tplants.2007.11.012. Epub 2008 Feb 14. Review.

PMID:
18280199
19.

The missing step of the L-galactose pathway of ascorbate biosynthesis in plants, an L-galactose guanyltransferase, increases leaf ascorbate content.

Laing WA, Wright MA, Cooney J, Bulley SM.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9534-9. Epub 2007 May 7.

20.

Pharmacogenomics and nutrigenomics: synergies and differences.

Ghosh D, Skinner MA, Laing WA.

Eur J Clin Nutr. 2007 May;61(5):567-74. Epub 2007 Jan 10. Review.

PMID:
17213870
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