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Items: 1 to 20 of 176

1.

CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection.

Côme C, Cvrljevic A, Khan MM, Treise I, Adler T, Aguilar-Pimentel JA, Au-Yeung B, Sittig E, Laajala TD, Chen Y, Oeder S, Calzada-Wack J, Horsch M, Aittokallio T, Busch DH, Ollert MW, Neff F, Beckers J, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Chen Z, Lahesmaa R, Westermarck J.

PLoS One. 2016 Apr 21;11(4):e0152996. doi: 10.1371/journal.pone.0152996. eCollection 2016.

2.

Comparative analysis of human and mouse transcriptomes of Th17 cell priming.

Tuomela S, Rautio S, Ahlfors H, Öling V, Salo V, Ullah U, Chen Z, Hämälistö S, Tripathi SK, Äijö T, Rasool O, Soueidan H, Wessels L, Stockinger B, Lähdesmäki H, Lahesmaa R.

Oncotarget. 2016 Mar 7. doi: 10.18632/oncotarget.7963. [Epub ahead of print]

3.

Epigenetic Silencing of the Key Antioxidant Enzyme Catalase in Karyotypically Abnormal Human Pluripotent Stem Cells.

Konki M, Pasumarthy K, Malonzo M, Sainio A, Valensisi C, Söderström M, Emani MR, Stubb A, Närvä E, Ghimire B, Laiho A, Järveläinen H, Lahesmaa R, Lähdesmäki H, Hawkins RD, Lund RJ.

Sci Rep. 2016 Feb 25;6:22190. doi: 10.1038/srep22190.

4.

Identification of global regulators of T-helper cell lineage specification.

Kanduri K, Tripathi S, Larjo A, Mannerström H, Ullah U, Lund R, Hawkins RD, Ren B, Lähdesmäki H, Lahesmaa R.

Genome Med. 2015 Nov 20;7:122. doi: 10.1186/s13073-015-0237-0.

5.

Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data.

Intosalmi J, Ahlfors H, Rautio S, Mannerstöm H, Chen ZJ, Lahesmaa R, Stockinger B, Lähdesmäki H.

BMC Syst Biol. 2015 Nov 17;9:81. doi: 10.1186/s12918-015-0223-6.

6.

A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.

Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M.

Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722.

PMID:
26560356
7.

New Insights and Biomarkers for Type 1 Diabetes: Review for Scandinavian Journal of Immunology.

Heinonen MT, Moulder R, Lahesmaa R.

Scand J Immunol. 2015 Sep;82(3):244-53. doi: 10.1111/sji.12338. Review.

PMID:
26119046
8.

GIMAP GTPase family genes: potential modifiers in autoimmune diabetes, asthma, and allergy.

Heinonen MT, Laine AP, Söderhäll C, Gruzieva O, Rautio S, Melén E, Pershagen G, Lähdesmäki HJ, Knip M, Ilonen J, Henttinen TA, Kere J, Lahesmaa R; Finnish Pediatric Diabetes Registry.

J Immunol. 2015 Jun 15;194(12):5885-94. doi: 10.4049/jimmunol.1500016. Epub 2015 May 11.

9.

The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency.

Emani MR, Närvä E, Stubb A, Chakroborty D, Viitala M, Rokka A, Rahkonen N, Moulder R, Denessiouk K, Trokovic R, Lund R, Elo LL, Lahesmaa R.

Stem Cell Reports. 2015 Mar 10;4(3):519-28. doi: 10.1016/j.stemcr.2015.01.014. Epub 2015 Feb 19.

10.

Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells.

Laurila K, Autio R, Kong L, Närvä E, Hussein S, Otonkoski T, Lahesmaa R, Lähdesmäki H.

BioData Min. 2014 Dec 13;7(1):32. doi: 10.1186/s13040-014-0032-2. eCollection 2014.

11.

Serum proteomes distinguish children developing type 1 diabetes in a cohort with HLA-conferred susceptibility.

Moulder R, Bhosale SD, Erkkilä T, Laajala E, Salmi J, Nguyen EV, Kallionpää H, Mykkänen J, Vähä-Mäkilä M, Hyöty H, Veijola R, Ilonen J, Simell T, Toppari J, Knip M, Goodlett DR, Lähdesmäki H, Simell O, Lahesmaa R.

Diabetes. 2015 Jun;64(6):2265-78. doi: 10.2337/db14-0983. Epub 2015 Jan 23.

12.

Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity.

Hrdlickova B, Kumar V, Kanduri K, Zhernakova DV, Tripathi S, Karjalainen J, Lund RJ, Li Y, Ullah U, Modderman R, Abdulahad W, Lähdesmäki H, Franke L, Lahesmaa R, Wijmenga C, Withoff S.

Genome Med. 2014 Oct 28;6(10):88. doi: 10.1186/s13073-014-0088-0. eCollection 2014.

13.

Tubulin- and actin-associating GIMAP4 is required for IFN-γ secretion during Th cell differentiation.

Heinonen MT, Kanduri K, Lähdesmäki HJ, Lahesmaa R, Henttinen TA.

Immunol Cell Biol. 2015 Feb;93(2):158-66. doi: 10.1038/icb.2014.86. Epub 2014 Oct 7.

14.

Standard of hygiene and immune adaptation in newborn infants.

Kallionpää H, Laajala E, Öling V, Härkönen T, Tillmann V, Dorshakova NV, Ilonen J, Lähdesmäki H, Knip M, Lahesmaa R; DIABIMMUNE Study Group.

Clin Immunol. 2014 Nov;155(1):136-47. doi: 10.1016/j.clim.2014.09.009. Epub 2014 Sep 22.

15.

Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels.

Kumar V, Gutierrez-Achury J, Kanduri K, Almeida R, Hrdlickova B, Zhernakova DV, Westra HJ, Karjalainen J, Ricaño-Ponce I, Li Y, Stachurska A, Tigchelaar EF, Abdulahad WH, Lähdesmäki H, Hofker MH, Zhernakova A, Franke L, Lahesmaa R, Wijmenga C, Withoff S.

Hum Mol Genet. 2015 Jan 15;24(2):397-409. doi: 10.1093/hmg/ddu453. Epub 2014 Sep 4.

16.

Transcriptional and epigenetic regulation of T-helper lineage specification.

Tripathi SK, Lahesmaa R.

Immunol Rev. 2014 Sep;261(1):62-83. doi: 10.1111/imr.12204. Review.

17.

The regulation and role of c-FLIP in human Th cell differentiation.

Kyläniemi MK, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R.

PLoS One. 2014 Jul 14;9(7):e102022. doi: 10.1371/journal.pone.0102022. eCollection 2014.

18.

Methods for time series analysis of RNA-seq data with application to human Th17 cell differentiation.

Äijö T, Butty V, Chen Z, Salo V, Tripathi S, Burge CB, Lahesmaa R, Lähdesmäki H.

Bioinformatics. 2014 Jun 15;30(12):i113-20. doi: 10.1093/bioinformatics/btu274.

19.

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.

Kelkka T, Kienhöfer D, Hoffmann M, Linja M, Wing K, Sareila O, Hultqvist M, Laajala E, Chen Z, Vasconcelos J, Neves E, Guedes M, Marques L, Krönke G, Helminen M, Kainulainen L, Olofsson P, Jalkanen S, Lahesmaa R, Souto-Carneiro MM, Holmdahl R.

Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29.

20.

Identification of Sphingomyelinase on the Surface of Chlamydia pneumoniae: Possible Role in the Entry into Its Host Cells.

Peñate Medina TA, Korhonen JT, Lahesmaa R, Puolakkainen M, Peñate Medina O, Kinnunen PK.

Interdiscip Perspect Infect Dis. 2014;2014:412827. doi: 10.1155/2014/412827. Epub 2014 Mar 13.

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