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Results: 1 to 20 of 62

1.

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.

Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ.

Mol Neurodegener. 2014 Apr 28;9:15. doi: 10.1186/1750-1326-9-15.

PMID:
24773620
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model.

Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ.

J Neurosci. 2013 Dec 4;33(49):19086-98. doi: 10.1523/JNEUROSCI.2508-13.2013.

PMID:
24305806
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.

Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16562-7. doi: 10.1073/pnas.1310249110. Epub 2013 Sep 10.

PMID:
24023061
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Neuron enriched nuclear proteome isolated from human brain.

Dammer EB, Duong DM, Diner I, Gearing M, Feng Y, Lah JJ, Levey AI, Seyfried NT.

J Proteome Res. 2013 Jul 5;12(7):3193-206. doi: 10.1021/pr400246t. Epub 2013 Jun 17.

PMID:
23768213
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.

Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ.

Alzheimers Res Ther. 2013 Jun 13;5(3):32. doi: 10.1186/alzrt186. eCollection 2013.

PMID:
23764030
[PubMed]
Free PMC Article
6.

NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.

Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R.

Neurosci Lett. 2013 Jun 28;547:16-20. doi: 10.1016/j.neulet.2013.04.056. Epub 2013 May 10.

PMID:
23669642
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Proteomic analysis of postsynaptic density in Alzheimer's disease.

Zhou J, Jones DR, Duong DM, Levey AI, Lah JJ, Peng J.

Clin Chim Acta. 2013 May;420:62-8. doi: 10.1016/j.cca.2013.03.016. Epub 2013 Mar 26.

PMID:
23537733
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Behavior matters--cognitive predictors of survival in amyotrophic lateral sclerosis.

Hu WT, Shelnutt M, Wilson A, Yarab N, Kelly C, Grossman M, Libon DJ, Khan J, Lah JJ, Levey AI, Glass J.

PLoS One. 2013;8(2):e57584. doi: 10.1371/journal.pone.0057584. Epub 2013 Feb 27.

PMID:
23460879
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells.

Pranski EL, Dalal NV, Sanford CV, Herskowitz JH, Gearing M, Lazo C, Miller GW, Lah JJ, Levey AI, Betarbet RS.

Neurobiol Dis. 2013 Jun;54:264-79. doi: 10.1016/j.nbd.2012.12.018. Epub 2013 Jan 11.

PMID:
23318928
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A behavioral task predicts conversion to mild cognitive impairment and Alzheimer's disease.

Zola SM, Manzanares CM, Clopton P, Lah JJ, Levey AI.

Am J Alzheimers Dis Other Demen. 2013 Mar;28(2):179-84. doi: 10.1177/1533317512470484. Epub 2012 Dec 26.

PMID:
23271330
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Variant of TREM2 associated with the risk of Alzheimer's disease.

Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K.

N Engl J Med. 2013 Jan 10;368(2):107-16. doi: 10.1056/NEJMoa1211103. Epub 2012 Nov 14.

PMID:
23150908
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

RNF11 modulates microglia activation through NF-κB signalling cascade.

Dalal NV, Pranski EL, Tansey MG, Lah JJ, Levey AI, Betarbet RS.

Neurosci Lett. 2012 Oct 24;528(2):174-9. doi: 10.1016/j.neulet.2012.08.060. Epub 2012 Sep 11.

PMID:
22975135
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains.

Sager KL, Wuu J, Herskowitz JH, Mufson EJ, Levey AI, Lah JJ.

PLoS One. 2012;7(8):e40527. doi: 10.1371/journal.pone.0040527. Epub 2012 Aug 21.

PMID:
22927900
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.

Dammer EB, Fallini C, Gozal YM, Duong DM, Rossoll W, Xu P, Lah JJ, Levey AI, Peng J, Bassell GJ, Seyfried NT.

PLoS One. 2012;7(6):e38658. doi: 10.1371/journal.pone.0038658. Epub 2012 Jun 21.

PMID:
22761693
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Asparaginyl endopeptidase cleaves TDP-43 in brain.

Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT.

Proteomics. 2012 Aug;12(15-16):2455-63. doi: 10.1002/pmic.201200006.

PMID:
22718532
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.

Pranski EL, Van Sanford CD, Dalal NV, Orr AL, Karmali D, Cooper DS, Costa N, Heilman CJ, Gearing M, Lah JJ, Levey AI, Betarbet RS.

Neurosci Lett. 2012 Jun 27;520(1):104-9. doi: 10.1016/j.neulet.2012.05.043. Epub 2012 May 23.

PMID:
22634524
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.

Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ.

Mol Biol Cell. 2012 Jul;23(14):2645-57. doi: 10.1091/mbc.E12-01-0014. Epub 2012 May 23.

PMID:
22621900
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.

Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI.

Proteomics Clin Appl. 2012 Apr;6(3-4):201-11. doi: 10.1002/prca.201100068.

PMID:
22532456
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.

Pranski EL, Dalal NV, Herskowitz JH, Orr AL, Roesch LA, Fritz JJ, Heilman C, Lah JJ, Levey AI, Betarbet RS.

J Neuroinflammation. 2012 Apr 16;9:67. doi: 10.1186/1742-2094-9-67.

PMID:
22507528
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards.

Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, Feng Y, Levey AI, Peng J.

J Proteome Res. 2012 May 4;11(5):2721-38. doi: 10.1021/pr2010814. Epub 2012 Apr 4.

PMID:
22416763
[PubMed - indexed for MEDLINE]
Free PMC Article

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