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Items: 1 to 20 of 33


Hierarchical boosting: a machine-learning framework to detect and classify hard selective sweeps in human populations.

Pybus M, Luisi P, Dall'Olio GM, Uzkudun M, Laayouni H, Bertranpetit J, Engelken J.

Bioinformatics. 2015 Dec 15;31(24):3946-52. doi: 10.1093/bioinformatics/btv493. Epub 2015 Aug 26.


The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape.

Dobon B, Hassan HY, Laayouni H, Luisi P, Ricaño-Ponce I, Zhernakova A, Wijmenga C, Tahir H, Comas D, Netea MG, Bertranpetit J.

Sci Rep. 2015 May 28;5:9996. doi: 10.1038/srep09996.


Recent positive selection has acted on genes encoding proteins with more interactions within the whole human interactome.

Luisi P, Alvarez-Ponce D, Pybus M, Fares MA, Bertranpetit J, Laayouni H.

Genome Biol Evol. 2015 Apr 2;7(4):1141-54. doi: 10.1093/gbe/evv055.


Balancing immunity and tolerance: genetic footprint of natural selection in the transcriptional regulatory region of HLA-G.

Gineau L, Luisi P, Castelli EC, Milet J, Courtin D, Cagnin N, Patillon B, Laayouni H, Moreau P, Donadi EA, Garcia A, Sabbagh A.

Genes Immun. 2015 Jan-Feb;16(1):57-70. doi: 10.1038/gene.2014.63. Epub 2014 Nov 13.


VCF2Networks: applying genotype networks to single-nucleotide variants data.

Dall'Olio GM, Vahdati AR, Bertranpetit J, Wagner A, Laayouni H.

Bioinformatics. 2015 Feb 1;31(3):438-9. doi: 10.1093/bioinformatics/btu650. Epub 2014 Oct 4.


Population and genomic lessons from genetic analysis of two Indian populations.

Juyal G, Mondal M, Luisi P, Laayouni H, Sood A, Midha V, Heutink P, Bertranpetit J, Thelma BK, Casals F.

Hum Genet. 2014 Oct;133(10):1273-87. doi: 10.1007/s00439-014-1462-0. Epub 2014 Jul 1.


Human genome variation and the concept of genotype networks.

Dall'Olio GM, Bertranpetit J, Wagner A, Laayouni H.

PLoS One. 2014 Jun 9;9(6):e99424. doi: 10.1371/journal.pone.0099424. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e107347.


Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors.

Laayouni H, Oosting M, Luisi P, Ioana M, Alonso S, Ricaño-Ponce I, Trynka G, Zhernakova A, Plantinga TS, Cheng SC, van der Meer JW, Popp R, Sood A, Thelma BK, Wijmenga C, Joosten LA, Bertranpetit J, Netea MG.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2668-73. doi: 10.1073/pnas.1317723111. Epub 2014 Feb 3.


Worldwide genetic variation at the 3' untranslated region of the HLA-G gene: balancing selection influencing genetic diversity.

Sabbagh A, Luisi P, Castelli EC, Gineau L, Courtin D, Milet J, Massaro JD, Laayouni H, Moreau P, Donadi EA, Garcia A.

Genes Immun. 2014 Mar;15(2):95-106. doi: 10.1038/gene.2013.67. Epub 2013 Dec 19.


1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans.

Pybus M, Dall'Olio GM, Luisi P, Uzkudun M, Carreño-Torres A, Pavlidis P, Laayouni H, Bertranpetit J, Engelken J.

Nucleic Acids Res. 2014 Jan;42(Database issue):D903-9. doi: 10.1093/nar/gkt1188. Epub 2013 Nov 25.


Metabolic flux is a determinant of the evolutionary rates of enzyme-encoding genes.

Colombo M, Laayouni H, Invergo BM, Bertranpetit J, Montanucci L.

Evolution. 2014 Feb;68(2):605-13. doi: 10.1111/evo.12262. Epub 2013 Sep 19.


Great ape genetic diversity and population history.

Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, Hobolth A, Halager AE, Malig M, Hernandez-Rodriguez J, Hernando-Herraez I, Prüfer K, Pybus M, Johnstone L, Lachmann M, Alkan C, Twigg D, Petit N, Baker C, Hormozdiari F, Fernandez-Callejo M, Dabad M, Wilson ML, Stevison L, Camprubí C, Carvalho T, Ruiz-Herrera A, Vives L, Mele M, Abello T, Kondova I, Bontrop RE, Pusey A, Lankester F, Kiyang JA, Bergl RA, Lonsdorf E, Myers S, Ventura M, Gagneux P, Comas D, Siegismund H, Blanc J, Agueda-Calpena L, Gut M, Fulton L, Tishkoff SA, Mullikin JC, Wilson RK, Gut IG, Gonder MK, Ryder OA, Hahn BH, Navarro A, Akey JM, Bertranpetit J, Reich D, Mailund T, Schierup MH, Hvilsom C, Andrés AM, Wall JD, Bustamante CD, Hammer MF, Eichler EE, Marques-Bonet T.

Nature. 2013 Jul 25;499(7459):471-5. doi: 10.1038/nature12228. Epub 2013 Jul 3.


A system-level, molecular evolutionary analysis of mammalian phototransduction.

Invergo BM, Montanucci L, Laayouni H, Bertranpetit J.

BMC Evol Biol. 2013 Feb 23;13:52. doi: 10.1186/1471-2148-13-52.


Distribution of events of positive selection and population differentiation in a metabolic pathway: the case of asparagine N-glycosylation.

Dall'Olio GM, Laayouni H, Luisi P, Sikora M, Montanucci L, Bertranpetit J.

BMC Evol Biol. 2012 Jun 25;12:98. doi: 10.1186/1471-2148-12-98.


Network-level and population genetics analysis of the insulin/TOR signal transduction pathway across human populations.

Luisi P, Alvarez-Ponce D, Dall'Olio GM, Sikora M, Bertranpetit J, Laayouni H.

Mol Biol Evol. 2012 May;29(5):1379-92. doi: 10.1093/molbev/msr298. Epub 2011 Dec 1.


Ten simple rules for getting help from online scientific communities.

Dall'Olio GM, Marino J, Schubert M, Keys KL, Stefan MI, Gillespie CS, Poulain P, Shameer K, Sugar R, Invergo BM, Jensen LJ, Bertranpetit J, Laayouni H.

PLoS Comput Biol. 2011 Sep;7(9):e1002202. doi: 10.1371/journal.pcbi.1002202. Epub 2011 Sep 29. No abstract available.


A targeted association study of immunity genes and networks suggests novel associations with placental malaria infection.

Sikora M, Laayouni H, Menendez C, Mayor A, Bardaji A, Sigauque B, Netea MG, Casals F, Bertranpetit J.

PLoS One. 2011;6(9):e24996. doi: 10.1371/journal.pone.0024996. Epub 2011 Sep 19.


Genetic adaptation of the antibacterial human innate immunity network.

Casals F, Sikora M, Laayouni H, Montanucci L, Muntasell A, Lazarus R, Calafell F, Awadalla P, Netea MG, Bertranpetit J.

BMC Evol Biol. 2011 Jul 11;11:202. doi: 10.1186/1471-2148-11-202.


Similarity in recombination rate estimates highly correlates with genetic differentiation in humans.

Laayouni H, Montanucci L, Sikora M, Melé M, Dall'Olio GM, Lorente-Galdos B, McGee KM, Graffelman J, Awadalla P, Bosch E, Comas D, Navarro A, Calafell F, Casals F, Bertranpetit J.

PLoS One. 2011 Mar 28;6(3):e17913. doi: 10.1371/journal.pone.0017913.


The annotation of the asparagine N-linked glycosylation pathway in the Reactome database.

Dall'Olio GM, Jassal B, Montanucci L, Gagneux P, Bertranpetit J, Laayouni H.

Glycobiology. 2011 Nov;21(11):1395-400. doi: 10.1093/glycob/cwq215. Epub 2011 Jan 2.

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