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Results: 1 to 20 of 72


MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons.

Lee W, Yun JM, Woods R, Dunaway K, Yasui DH, Lasalle JM, Gong Q.

Hum Mol Genet. 2014 Dec 1;23(23):6366-74. doi: 10.1093/hmg/ddu358. Epub 2014 Jul 9.


Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease.

Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, LaSalle JM, Halsted CH, Keen CL, Medici V.

Int J Mol Sci. 2014 May 7;15(5):8004-23. doi: 10.3390/ijms15058004.


Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis.

Selmi C, Cavaciocchi F, Lleo A, Cheroni C, De Francesco R, Lombardi SA, De Santis M, Meda F, Raimondo MG, Crotti C, Folci M, Zammataro L, Mayo MJ, Bach N, Shimoda S, Gordon SC, Miozzo M, Invernizzi P, Podda M, Scavelli R, Martin MR, Seldin MF, Lasalle JM, Gershwin ME.

Front Immunol. 2014 Mar 28;5:128. doi: 10.3389/fimmu.2014.00128. eCollection 2014. Erratum in: Front Immunol. 2014;5:371. Seldin, Michael F [added].


Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.

Medici V, Schroeder DI, Woods R, LaSalle JM, Geng Y, Shibata NM, Peerson J, Hodzic E, Dayal S, Tsukamoto H, Kharbanda KK, Tillman B, French SW, Halsted CH.

Alcohol Clin Exp Res. 2014 Jun;38(6):1540-9. doi: 10.1111/acer.12405. Epub 2014 Apr 14.


Autism genes keep turning up chromatin.

Lasalle JM.

OA Autism. 2013 Jun 19;1(2):14.


Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome.

Yasui DH, Gonzales ML, Aflatooni JO, Crary FK, Hu DJ, Gavino BJ, Golub MS, Vincent JB, Carolyn Schanen N, Olson CO, Rastegar M, Lasalle JM.

Hum Mol Genet. 2014 May 1;23(9):2447-58. doi: 10.1093/hmg/ddt640. Epub 2013 Dec 18. Erratum in: Hum Mol Genet. 2014 Dec 15;23(24):6695.


How has the study of the human placenta aided our understanding of partially methylated genes?

Schroeder DI, LaSalle JM.

Epigenomics. 2013 Dec;5(6):645-54. doi: 10.2217/epi.13.62.


Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease.

Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM.

Epigenetics. 2014 Feb;9(2):286-96. doi: 10.4161/epi.27110. Epub 2013 Nov 12.


R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.

Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13938-43. doi: 10.1073/pnas.1305426110. Epub 2013 Aug 5.


A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure.

Powell WT, Coulson RL, Crary FK, Wong SS, Ach RA, Tsang P, Alice Yamada N, Yasui DH, Lasalle JM.

Hum Mol Genet. 2013 Nov 1;22(21):4318-28. doi: 10.1093/hmg/ddt281. Epub 2013 Jun 13.


Epigenetic layers and players underlying neurodevelopment.

LaSalle JM, Powell WT, Yasui DH.

Trends Neurosci. 2013 Aug;36(8):460-70. doi: 10.1016/j.tins.2013.05.001. Epub 2013 May 31. Review.


Epigenomic strategies at the interface of genetic and environmental risk factors for autism.

LaSalle JM.

J Hum Genet. 2013 Jul;58(7):396-401. doi: 10.1038/jhg.2013.49. Epub 2013 May 16. Review.


The human placenta methylome.

Schroeder DI, Blair JD, Lott P, Yu HO, Hong D, Crary F, Ashwood P, Walker C, Korf I, Robinson WP, LaSalle JM.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6037-42. doi: 10.1073/pnas.1215145110. Epub 2013 Mar 25.


MeCP2 modulates gene expression pathways in astrocytes.

Yasui DH, Xu H, Dunaway KW, Lasalle JM, Jin LW, Maezawa I.

Mol Autism. 2013 Jan 25;4(1):3. doi: 10.1186/2040-2392-4-3.


Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.

Medici V, Shibata NM, Kharbanda KK, LaSalle JM, Woods R, Liu S, Engelberg JA, Devaraj S, Török NJ, Jiang JX, Havel PJ, Lönnerdal B, Kim K, Halsted CH.

Hepatology. 2013 Feb;57(2):555-65. doi: 10.1002/hep.26047. Epub 2013 Jan 10.


Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder.

Mitchell MM, Woods R, Chi LH, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM.

Environ Mol Mutagen. 2012 Oct;53(8):589-98. doi: 10.1002/em.21722. Epub 2012 Aug 29.


X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma.

Selmi C, Feghali-Bostwick CA, Lleo A, Lombardi SA, De Santis M, Cavaciocchi F, Zammataro L, Mitchell MM, Lasalle JM, Medsger T Jr, Gershwin ME.

Clin Exp Immunol. 2012 Sep;169(3):253-62. doi: 10.1111/j.1365-2249.2012.04621.x.


Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation.

Gonzales ML, Adams S, Dunaway KW, LaSalle JM.

Mol Cell Biol. 2012 Jul;32(14):2894-903. doi: 10.1128/MCB.06728-11. Epub 2012 May 21.


Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation.

Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, LaSalle JM.

Hum Mol Genet. 2012 Jun 1;21(11):2399-411. doi: 10.1093/hmg/dds046. Epub 2012 Feb 15.


Role of DNMT3B in the regulation of early neural and neural crest specifiers.

Martins-Taylor K, Schroeder DI, LaSalle JM, Lalande M, Xu RH.

Epigenetics. 2012 Jan 1;7(1):71-82. doi: 10.4161/epi.7.1.18750. Epub 2012 Jan 1.

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