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Sequence features accurately predict genome-wide MeCP2 binding in vivo.

Rube HT, Lee W, Hejna M, Chen H, Yasui DH, Hess JF, LaSalle JM, Song JS, Gong Q.

Nat Commun. 2016 Mar 24;7:11025. doi: 10.1038/ncomms11025.


Autism and Cancer Share Risk Genes, Pathways, and Drug Targets.

Crawley JN, Heyer WD, LaSalle JM.

Trends Genet. 2016 Mar;32(3):139-46. doi: 10.1016/j.tig.2016.01.001. Epub 2016 Jan 29.


Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.

LaSalle JM, Reiter LT, Chamberlain SJ.

Epigenomics. 2015 Oct;7(7):1213-28. doi: 10.2217/epi.15.70. Epub 2015 Nov 20.


Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas.

Schroeder DI, Jayashankar K, Douglas KC, Thirkill TL, York D, Dickinson PJ, Williams LE, Samollow PB, Ross PJ, Bannasch DL, Douglas GC, LaSalle JM.

PLoS Genet. 2015 Aug 4;11(8):e1005442. doi: 10.1371/journal.pgen.1005442. eCollection 2015 Aug.


Epigenetic mechanisms in diurnal cycles of metabolism and neurodevelopment.

Powell WT, LaSalle JM.

Hum Mol Genet. 2015 Oct 15;24(R1):R1-9. doi: 10.1093/hmg/ddv234. Epub 2015 Jun 23. Review.


Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity.

Li MM, Addepalli B, Tu MJ, Chen QX, Wang WP, Limbach PA, LaSalle JM, Zeng S, Huang M, Yu AM.

Drug Metab Dispos. 2015 Jul;43(7):1129-36. doi: 10.1124/dmd.115.064493. Epub 2015 May 1.


MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons.

Lee W, Yun JM, Woods R, Dunaway K, Yasui DH, Lasalle JM, Gong Q.

Hum Mol Genet. 2014 Dec 1;23(23):6366-74. doi: 10.1093/hmg/ddu358. Epub 2014 Jul 9.


Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease.

Le A, Shibata NM, French SW, Kim K, Kharbanda KK, Islam MS, LaSalle JM, Halsted CH, Keen CL, Medici V.

Int J Mol Sci. 2014 May 7;15(5):8004-23. doi: 10.3390/ijms15058004.


Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis.

Selmi C, Cavaciocchi F, Lleo A, Cheroni C, De Francesco R, Lombardi SA, De Santis M, Meda F, Raimondo MG, Crotti C, Folci M, Zammataro L, Mayo MJ, Bach N, Shimoda S, Gordon SC, Miozzo M, Invernizzi P, Podda M, Scavelli R, Martin MR, Seldin MF, Lasalle JM, Gershwin ME.

Front Immunol. 2014 Mar 28;5:128. doi: 10.3389/fimmu.2014.00128. eCollection 2014. Erratum in: Front Immunol. 2014;5:371. Seldin, Michael F [added].


Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.

Medici V, Schroeder DI, Woods R, LaSalle JM, Geng Y, Shibata NM, Peerson J, Hodzic E, Dayal S, Tsukamoto H, Kharbanda KK, Tillman B, French SW, Halsted CH.

Alcohol Clin Exp Res. 2014 Jun;38(6):1540-9. doi: 10.1111/acer.12405. Epub 2014 Apr 14.


Autism genes keep turning up chromatin.

Lasalle JM.

OA Autism. 2013 Jun 19;1(2):14.


Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome.

Yasui DH, Gonzales ML, Aflatooni JO, Crary FK, Hu DJ, Gavino BJ, Golub MS, Vincent JB, Carolyn Schanen N, Olson CO, Rastegar M, Lasalle JM.

Hum Mol Genet. 2014 May 1;23(9):2447-58. doi: 10.1093/hmg/ddt640. Epub 2013 Dec 18. Erratum in: Hum Mol Genet. 2014 Dec 15;23(24):6695.


How has the study of the human placenta aided our understanding of partially methylated genes?

Schroeder DI, LaSalle JM.

Epigenomics. 2013 Dec;5(6):645-54. doi: 10.2217/epi.13.62.


Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease.

Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM.

Epigenetics. 2014 Feb;9(2):286-96. doi: 10.4161/epi.27110. Epub 2013 Nov 12.


R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.

Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13938-43. doi: 10.1073/pnas.1305426110. Epub 2013 Aug 5.


A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure.

Powell WT, Coulson RL, Crary FK, Wong SS, Ach RA, Tsang P, Alice Yamada N, Yasui DH, Lasalle JM.

Hum Mol Genet. 2013 Nov 1;22(21):4318-28. doi: 10.1093/hmg/ddt281. Epub 2013 Jun 13.


Epigenetic layers and players underlying neurodevelopment.

LaSalle JM, Powell WT, Yasui DH.

Trends Neurosci. 2013 Aug;36(8):460-70. doi: 10.1016/j.tins.2013.05.001. Epub 2013 May 31. Review.


Epigenomic strategies at the interface of genetic and environmental risk factors for autism.

LaSalle JM.

J Hum Genet. 2013 Jul;58(7):396-401. doi: 10.1038/jhg.2013.49. Epub 2013 May 16. Review.


The human placenta methylome.

Schroeder DI, Blair JD, Lott P, Yu HO, Hong D, Crary F, Ashwood P, Walker C, Korf I, Robinson WP, LaSalle JM.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6037-42. doi: 10.1073/pnas.1215145110. Epub 2013 Mar 25.


MeCP2 modulates gene expression pathways in astrocytes.

Yasui DH, Xu H, Dunaway KW, Lasalle JM, Jin LW, Maezawa I.

Mol Autism. 2013 Jan 25;4(1):3. doi: 10.1186/2040-2392-4-3.

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