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Page 1
Lyzl4, a novel mouse sperm-related protein, is involved in fertilization.
Sun R, Shen R, Li J, Xu G, Chi J, Li L, Ren J, Wang Z, Fei J. Sun R, et al. Acta Biochim Biophys Sin (Shanghai). 2011 May;43(5):346-53. doi: 10.1093/abbs/gmr017. Epub 2011 Mar 28. Acta Biochim Biophys Sin (Shanghai). 2011. PMID: 21444326 Free article.
The mature recombinant Lyzl4 protein expressed in yeast did not show the bacteriolytic activity. ...Immuno-neutralization of Lyzl4 protein in spermatozoa with its specific antibody significantly decreased in vitro fertilization percentage in a dose-dependent manner, …
The mature recombinant Lyzl4 protein expressed in yeast did not show the bacteriolytic activity. ...Immuno-neutralization of Lyzl4 …
[Preparation of a polyclonal antibody against human LYZL4 and its expression in the testis].
Huang P, Yang ZF, Xu YX, Bao JY, Zhang N, Cao XE, Li WS. Huang P, et al. Zhonghua Nan Ke Xue. 2017 Jan;23(1):3-10. Zhonghua Nan Ke Xue. 2017. PMID: 29658230 Chinese.
OBJECTIVE: To prepare a polyclonal antibody against human lysozyme-like protein 4 (LYZL4) expressed in the prokaryotic system and identify the distribution of LYZL4 in the testis. METHODS: The full-length cDNA of LYZL4 was cloned into the pET32a plasmid and t …
OBJECTIVE: To prepare a polyclonal antibody against human lysozyme-like protein 4 (LYZL4) expressed in the prokaryotic system and ide …
Structural, Functional and Phylogenetic Analysis of Sperm Lysozyme-Like Proteins.
Kalra S, Pradeep MA, Mohanty AK, Kaushik JK. Kalra S, et al. PLoS One. 2016 Nov 10;11(11):e0166321. doi: 10.1371/journal.pone.0166321. eCollection 2016. PLoS One. 2016. PMID: 27832206 Free PMC article.
Some studies suggested a role of SLLP1 and LYZL4 in fertilization; however, the function of other LYZL proteins is unknown. ...Residues at sites 62, 101, 114 in LYZL4; 101 in SLLP1; 37, 62, and 101 in LYZL6 were more variable among diverse species. ...
Some studies suggested a role of SLLP1 and LYZL4 in fertilization; however, the function of other LYZL proteins is unknown. ...Residu …
[The role of human lysozyme-like protein 4 in fertilization and its enzymatic properties].
Huang P, Qian N, DU WC, Shi WJ, Sun QW, Zhang N. Huang P, et al. Zhonghua Nan Ke Xue. 2018 Feb;24(2):109-115. Zhonghua Nan Ke Xue. 2018. PMID: 30156068 Chinese.
OBJECTIVE: To elucidate the possible role of human lysozyme-like protein 4 (LYZL4) in fertilization and characterize its enzymatic properties. METHODS: The localization of LYZL4 in human spermatozoa was investigated by immunofluorescence staining, the sources of …
OBJECTIVE: To elucidate the possible role of human lysozyme-like protein 4 (LYZL4) in fertilization and characterize its enzymatic pr …
Characterization of a novel lysozyme-like 4 gene in the rat.
Narmadha G, Muneswararao K, Rajesh A, Yenugu S. Narmadha G, et al. PLoS One. 2011;6(11):e27659. doi: 10.1371/journal.pone.0027659. Epub 2011 Nov 15. PLoS One. 2011. PMID: 22110709 Free PMC article.
Lyzl expression in the developing (10-60 day old) rats was androgen dependent in the testis. Immunodetection using antibodies against rat LYZL4 revealed the presence of LYZL4 protein in the germinal layer of the testes and on the sperm tail. Recombinant LYZL4 …
Lyzl expression in the developing (10-60 day old) rats was androgen dependent in the testis. Immunodetection using antibodies against rat …
Immunization against lysozyme-like proteins affect sperm function and fertility in the rat.
Narmadha G, Yenugu S. Narmadha G, et al. J Reprod Immunol. 2016 Nov;118:100-108. doi: 10.1016/j.jri.2016.11.001. Epub 2016 Nov 2. J Reprod Immunol. 2016. PMID: 27821286
Rats immunized with LYZL1, LYZL4 and LYZL6 proteins had a litter size of 5.93, 8.47 and 2.10 respectively compared to 9.96 in the control rats. ...Sperm count was significantly reduced in rats immunized with LYZL1 or LYZL6 and to a lower extent in LYZL4 group. Acros …
Rats immunized with LYZL1, LYZL4 and LYZL6 proteins had a litter size of 5.93, 8.47 and 2.10 respectively compared to 9.96 in the con …
In Silico and Biochemical Characterization of Lysozyme-Like Proteins in the Rat.
Narmadha G, Yenugu S. Narmadha G, et al. PLoS One. 2016 Sep 9;11(9):e0161909. doi: 10.1371/journal.pone.0161909. eCollection 2016. PLoS One. 2016. PMID: 27611690 Free PMC article.
Only LYZL1 and 6 possess peptidoglycan binding ability, whereas LYZL3, LYZL4 and LYZL5 possess hyaluronan binding ability suggesting a possible functional divergence of these proteins. LYZL3, LYZL4 and LYZL7 possessed free radical scavenging property, suggesting tha …
Only LYZL1 and 6 possess peptidoglycan binding ability, whereas LYZL3, LYZL4 and LYZL5 possess hyaluronan binding ability suggesting …
Differential Proteomic Analysis of Human Sperm: A Systematic Review to Identify Candidate Targets to Monitor Sperm Quality.
Corda PO, Moreira J, Howl J, Oliveira PF, Fardilha M, Silva JV. Corda PO, et al. World J Mens Health. 2024 Jan;42(1):71-91. doi: 10.5534/wjmh.220262. Epub 2023 Apr 20. World J Mens Health. 2024. PMID: 37118964 Free PMC article.
Among the identified proteins, ACR, ACRBP, ACRV1, ACTL9, AKAP4, ATG3, CCT2, CFAP276, CFAP52, FAM209A, GGH, HPRT1, LYZL4, PRDX6, PRSS37, REEP6, ROPN1B, SPACA3, SOD1, SPEM1, SPESP1, SPINK2, TEKT5, and ZPBP were highlighted due to their roles in male reproductive tissues, ass …
Among the identified proteins, ACR, ACRBP, ACRV1, ACTL9, AKAP4, ATG3, CCT2, CFAP276, CFAP52, FAM209A, GGH, HPRT1, LYZL4, PRDX6, PRSS3 …
Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family.
Zhang K, Gao R, Zhang H, Cai X, Shen C, Wu C, Zhao S, Yu L. Zhang K, et al. Biol Reprod. 2005 Nov;73(5):1064-71. doi: 10.1095/biolreprod.105.041889. Epub 2005 Jul 13. Biol Reprod. 2005. PMID: 16014814
Using Northern blot hybridization, including 16 different human tissues, we found that these four lysozyme-like genes were all highly expressed in the testis/epididymis. Further analysis of one, LYZL4, by in situ hybridization revealed that its mRNA was only detected in th …
Using Northern blot hybridization, including 16 different human tissues, we found that these four lysozyme-like genes were all highly expres …
Exome chip analyses identify genes affecting mortality after HLA-matched unrelated-donor blood and marrow transplantation.
Zhu Q, Yan L, Liu Q, Zhang C, Wei L, Hu Q, Preus L, Clay-Gilmour AI, Onel K, Stram DO, Pooler L, Sheng X, Haiman CA, Zhu X, Spellman SR, Pasquini M, McCarthy PL, Liu S, Hahn T, Sucheston-Campbell LE. Zhu Q, et al. Blood. 2018 May 31;131(22):2490-2499. doi: 10.1182/blood-2017-11-817973. Epub 2018 Apr 2. Blood. 2018. PMID: 29610366 Free PMC article.
In donors, 4 (ALPP, EMID1, SLC44A5, LRP1), 1 (HHAT), and 2 genes (LYZL4, NT5E) were significantly associated with OS, TRM, and DRM, respectively. ...
In donors, 4 (ALPP, EMID1, SLC44A5, LRP1), 1 (HHAT), and 2 genes (LYZL4, NT5E) were significantly associated with OS, TRM, and DRM, r …
13 results