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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1940 1
1947 1
1948 1
1960 1
1964 1
1966 1
1967 1
1968 7
1969 5
1970 3
1971 2
1972 1
1973 3
1974 2
1975 14
1976 15
1977 24
1978 15
1979 28
1980 24
1981 45
1982 39
1983 30
1984 43
1985 51
1986 58
1987 51
1988 63
1989 53
1990 62
1991 62
1992 76
1993 84
1994 73
1995 102
1996 100
1997 114
1998 119
1999 111
2000 91
2001 102
2002 85
2003 112
2004 121
2005 118
2006 110
2007 115
2008 116
2009 97
2010 132
2011 115
2012 126
2013 126
2014 110
2015 131
2016 121
2017 113
2018 121
2019 119
2020 108
2021 104
2022 122
2023 126
2024 39

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3,955 results

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Page 1
L-Glucose: Another Path to Cancer Cells.
Ono K, Takigawa S, Yamada K. Ono K, et al. Cancers (Basel). 2020 Apr 1;12(4):850. doi: 10.3390/cancers12040850. Cancers (Basel). 2020. PMID: 32244695 Free PMC article. Review.
Among numerous efforts to understand this property, little attention has been paid to the possibility that cancer cells take up and utilize otherwise unusable substrates as fuel. Here we discuss this issue by focusing on L-glucose, the mirror image isomer of natural …
Among numerous efforts to understand this property, little attention has been paid to the possibility that cancer cells take up and utilize …
The Use of L-Glucose in Cancer Diagnosis: Results from In Vitro and In Vivo Studies.
Anastasiou IA, Eleftheriadou I, Tentolouris A, Mourouzis I, Pantos C, Tentolouris N. Anastasiou IA, et al. Curr Med Chem. 2021;28(30):6110-6122. doi: 10.2174/0929867328666210311112240. Curr Med Chem. 2021. PMID: 33719949 Review.
CONCLUSION: Given that L-glucose is taken up by cancer cells, L-glucose fluorescent probes can be a useful tool for visualization and characterization of cancer cells. More research on the potential biologic effects of L-glucose in cancer …
CONCLUSION: Given that L-glucose is taken up by cancer cells, L-glucose fluorescent probes can be a useful tool …
Aberrant Uptake of a Fluorescent L-Glucose Analogue (fLG) into Tumor Cells Expressing Malignant Phenotypes.
Yamada K. Yamada K. Biol Pharm Bull. 2018;41(10):1508-1516. doi: 10.1248/bpb.b18-00089. Biol Pharm Bull. 2018. PMID: 30270319 Free article. Review.
Such stereoselective uptake of glucose has been explored by fluorophore-bearing D- and L-glucose analogues. 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose (2-NBDG), the most widely used fluorescent D-glucose analogue, was abundantly taken up into l …
Such stereoselective uptake of glucose has been explored by fluorophore-bearing D- and L-glucose analogues. 2-[N-(7-Nitrobenz- …
Taste and chirality: l-glucose sweetness is mediated by TAS1R2/TAS2R3 receptor.
Dubovski N, Ben Shoshan-Galeczki Y, Malach E, Niv MY. Dubovski N, et al. Food Chem. 2022 Mar 30;373(Pt A):131393. doi: 10.1016/j.foodchem.2021.131393. Epub 2021 Oct 13. Food Chem. 2022. PMID: 34715629
While a change in chirality typically affects ligand-receptor interaction, non-caloric l-glucose was reported as sweet for humans. Here we show that l- and d-glucose have similar sensory detection thresholds (0.041 0.006 M for d-glucose, and 0.032 0.007 M for l …
While a change in chirality typically affects ligand-receptor interaction, non-caloric l-glucose was reported as sweet for hum …
Unknown biological effects of L-glucose, ALA, and PUFA.
Yamada K, Sato D, Nakamura T, Amano H, Morimoto Y. Yamada K, et al. J Physiol Sci. 2017 Sep;67(5):539-548. doi: 10.1007/s12576-017-0544-x. Epub 2017 May 30. J Physiol Sci. 2017. PMID: 28560575 Free PMC article. Review.
In this review, we describe phenomena observed when key substrates are applied to cells. We focused on three promising substrates: L-glucose derivatives, 5-aminolevulinic acid, and polyunsaturated fatty acid. ...
In this review, we describe phenomena observed when key substrates are applied to cells. We focused on three promising substrates: L- …
alpha-L-glucose-1-phosphate.
POTTER AL, SOWDEN JC, et al. POTTER AL, et al. J Am Chem Soc. 1948 May;70(5):1751. doi: 10.1021/ja01185a023. J Am Chem Soc. 1948. PMID: 18861761 No abstract available.
Diboronate Fluorophore for the Measurement of l-Glucose and Other Carbohydrates and Its Interaction with Albumin.
Solomos K, Tarus V, Kotek V, Invernizzi G, Hoeg-Jensen T. Solomos K, et al. ACS Omega. 2022 Jul 6;7(28):24662-24668. doi: 10.1021/acsomega.2c02519. eCollection 2022 Jul 19. ACS Omega. 2022. PMID: 35874210 Free PMC article.
l-Glucose has recently been investigated as an artificial sweetener, but no facile method is established for the measurement of l-glucose. ...We thus designed a water-soluble anthracene diboronate 8 similar to the fluorophore used in Eversense and foun …
l-Glucose has recently been investigated as an artificial sweetener, but no facile method is established for the measurement o …
The riddle of L-glucose pentaacetate insulinotropic action (review).
Malaisse WJ. Malaisse WJ. Int J Mol Med. 1998 Oct;2(4):383-8. doi: 10.3892/ijmm.2.4.383. Int J Mol Med. 1998. PMID: 9857221 Review.
The two anomers of L-glucose pentaacetate were recently found to stimulate insulin release. ...It is proposed that the L-glucose pentaacetate anomers could be used as novel insulinotropic tools in the treatment of non-insulin-dependent diabetes mellitu …
The two anomers of L-glucose pentaacetate were recently found to stimulate insulin release. ...It is proposed that the L …
Gene switch for l-glucose-induced biopharmaceutical production in mammalian cells.
Strittmatter T, Egli S, Bertschi A, Plieninger R, Bojar D, Xie M, Fussenegger M. Strittmatter T, et al. Biotechnol Bioeng. 2021 Jun;118(6):2220-2233. doi: 10.1002/bit.27730. Epub 2021 Mar 18. Biotechnol Bioeng. 2021. PMID: 33629358
In this study, we designed and built a gene switch that employs metabolically inert l-glucose to regulate transgene expression in mammalian cells via d-idonate-mediated control of the bacterial regulator LgnR. To this end, we engineered a metabolic cascade in mammal …
In this study, we designed and built a gene switch that employs metabolically inert l-glucose to regulate transgene expression …
L-Chlorozotocin.
Johnston TP, McCaleb GS, Anderson T, Murinson DS. Johnston TP, et al. J Med Chem. 1979 May;22(5):597-9. doi: 10.1021/jm00191a030. J Med Chem. 1979. PMID: 156793
L-Chlorozotocin (2-[[[2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-L-glucose) was synthesized in seven steps from L-arabinose for comparison with chlorozotocin, which is the D enantiomorph and an antineoplastic agent with clinical potential. Purification of th …
L-Chlorozotocin (2-[[[2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-L-glucose) was synthesized in seven steps from L-arab …
3,955 results