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Results: 1 to 20 of 181


Lysosome fusion in cultured mammalian cells.

Bright NA, Wartosch L, Luzio JP.

Methods Cell Biol. 2015;126:101-18. doi: 10.1016/bs.mcb.2014.10.029. Epub 2015 Jan 14.


The biogenesis of lysosomes and lysosome-related organelles.

Luzio JP, Hackmann Y, Dieckmann NM, Griffiths GM.

Cold Spring Harb Perspect Biol. 2014 Sep 2;6(9):a016840. doi: 10.1101/cshperspect.a016840.


VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.

Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MN, Luzio JP, Owen DJ.

Dev Cell. 2014 Jun 9;29(5):591-606. doi: 10.1016/j.devcel.2014.04.010. Epub 2014 May 22.


The history of neurosurgery at the University of Sao Paulo.

Teixeira MJ, Figueiredo EG, Taricco MA, Plese JP, Flores C, Teixeira SA, Luzio J.

Arq Neuropsiquiatr. 2014 Mar;72(3):251-3.


Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.

Graham SC, Wartosch L, Gray SR, Scourfield EJ, Deane JE, Luzio JP, Owen DJ.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13345-50. doi: 10.1073/pnas.1307074110. Epub 2013 Jul 30.


Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.

Birchenough GM, Johansson ME, Stabler RA, Dalgakiran F, Hansson GC, Wren BW, Luzio JP, Taylor PW.

Infect Immun. 2013 Sep;81(9):3264-75. doi: 10.1128/IAI.00268-13. Epub 2013 Jun 24.


The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation.

Schäfer IB, Hesketh GG, Bright NA, Gray SR, Pryor PR, Evans PR, Luzio JP, Owen DJ.

Nat Struct Mol Biol. 2012 Dec;19(12):1300-9. doi: 10.1038/nsmb.2414. Epub 2012 Oct 28.


Structural basis of the intracellular sorting of the SNARE VAMP7 by the AP3 adaptor complex.

Kent HM, Evans PR, Schäfer IB, Gray SR, Sanderson CM, Luzio JP, Peden AA, Owen DJ.

Dev Cell. 2012 May 15;22(5):979-88. doi: 10.1016/j.devcel.2012.01.018. Epub 2012 Apr 19.


Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians.

Piers RD, Azoulay E, Ricou B, Dekeyser Ganz F, Decruyenaere J, Max A, Michalsen A, Maia PA, Owczuk R, Rubulotta F, Depuydt P, Meert AP, Reyners AK, Aquilina A, Bekaert M, Van den Noortgate NJ, Schrauwen WJ, Benoit DD; APPROPRICUS Study Group of the Ethics Section of the ESICM.

JAMA. 2011 Dec 28;306(24):2694-703. doi: 10.1001/jama.2011.1888.


Endosome-lysosome fusion.

Luzio JP, Gray SR, Bright NA.

Biochem Soc Trans. 2010 Dec;38(6):1413-6. doi: 10.1042/BST0381413.


The sodium/proton exchanger NHE8 regulates late endosomal morphology and function.

Lawrence SP, Bright NA, Luzio JP, Bowers K.

Mol Biol Cell. 2010 Oct 15;21(20):3540-51. doi: 10.1091/mbc.E09-12-1053. Epub 2010 Aug 18.


Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1.

Zelmer A, Martin MJ, Gundogdu O, Birchenough G, Lever R, Wren BW, Luzio JP, Taylor PW.

Microbiology. 2010 Jul;156(Pt 7):2205-15. doi: 10.1099/mic.0.036145-0. Epub 2010 Apr 15.


Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C.

Roberts RC, Peden AA, Buss F, Bright NA, Latouche M, Reilly MM, Kendrick-Jones J, Luzio JP.

Hum Mol Genet. 2010 Mar 15;19(6):1009-18. doi: 10.1093/hmg/ddp565. Epub 2009 Dec 22.


The delivery of endocytosed cargo to lysosomes.

Luzio JP, Parkinson MD, Gray SR, Bright NA.

Biochem Soc Trans. 2009 Oct;37(Pt 5):1019-21. doi: 10.1042/BST0371019. Review.


The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling.

Tsang HT, Edwards TL, Wang X, Connell JW, Davies RJ, Durrington HJ, O'Kane CJ, Luzio JP, Reid E.

Hum Mol Genet. 2009 Oct 15;18(20):3805-21. doi: 10.1093/hmg/ddp324. Epub 2009 Jul 20.


Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5.

Edwards TL, Clowes VE, Tsang HT, Connell JW, Sanderson CM, Luzio JP, Reid E.

Biochem J. 2009 Sep 14;423(1):31-9. doi: 10.1042/BJ20082398. Erratum in: Biochem J. 2009 Nov 1;423(3):442.


Delivery of endocytosed membrane proteins to the lysosome.

Pryor PR, Luzio JP.

Biochim Biophys Acta. 2009 Apr;1793(4):615-24. doi: 10.1016/j.bbamcr.2008.12.022. Epub 2009 Jan 8. Review.


ESCRT proteins and the regulation of endocytic delivery to lysosomes.

Luzio JP, Piper SC, Bowers K, Parkinson MD, Lehner PJ, Bright NA.

Biochem Soc Trans. 2009 Feb;37(Pt 1):178-80. doi: 10.1042/BST0370178.


Increased lipase and amilase levels in critically ill patients: retrospective study.

Ferreira M, Coelho R, Luzio J, Coutinho P.

Rev Bras Ter Intensiva. 2008 Dec;20(4):362-369. English, Portuguese.


Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion.

Connell JW, Lindon C, Luzio JP, Reid E.

Traffic. 2009 Jan;10(1):42-56. doi: 10.1111/j.1600-0854.2008.00847.x. Epub 2008 Oct 29.

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