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Results: 1 to 20 of 345

1.

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction.

Wallace DF, Secondes ES, Rishi G, Ostini L, McDonald CJ, Lane SW, Vu T, Hooper JD, Velasco G, Ramsay AJ, Lopez-Otin C, Subramaniam VN.

Br J Haematol. 2014 Nov 17. doi: 10.1111/bjh.13225. [Epub ahead of print]

PMID:
25403101
[PubMed - as supplied by publisher]
2.

Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy.

Valdés-Mas R, Gutiérrez-Fernández A, Gómez J, Coto E, Astudillo A, Puente DA, Reguero JR, Alvarez V, Morís C, León D, Martín M, Puente XS, López-Otín C.

Nat Commun. 2014 Oct 29;5:5326. doi: 10.1038/ncomms6326.

PMID:
25351925
[PubMed - in process]
3.

Comprehensive characterization of complex structural variations in cancer by directly comparing genome sequence reads.

Moncunill V, Gonzalez S, Beà S, Andrieux LO, Salaverria I, Royo C, Martinez L, Puiggròs M, Segura-Wang M, Stütz AM, Navarro A, Royo R, Gelpí JL, Gut IG, López-Otín C, Orozco M, Korbel JO, Campo E, Puente XS, Torrents D.

Nat Biotechnol. 2014 Nov;32(11):1106-12. doi: 10.1038/nbt.3027. Epub 2014 Oct 26.

PMID:
25344728
[PubMed - in process]
4.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2014 Sep 19. doi: 10.1038/cdd.2014.137. [Epub ahead of print] Review.

PMID:
25236395
[PubMed - as supplied by publisher]
5.

Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness.

Baixauli F, López-Otín C, Mittelbrunn M.

Front Immunol. 2014 Aug 20;5:403. doi: 10.3389/fimmu.2014.00403. eCollection 2014. Review.

PMID:
25191326
[PubMed]
Free PMC Article
6.

A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.

Queirós AC, Villamor N, Clot G, Martinez-Trillos A, Kulis M, Navarro A, Penas EM, Jayne S, Majid A, Richter J, Bergmann AK, Kolarova J, Royo C, Russiñol N, Castellano G, Pinyol M, Bea S, Salaverria I, López-Guerra M, Colomer D, Aymerich M, Rozman M, Delgado J, Giné E, González-Díaz M, Puente XS, Siebert R, Dyer MJ, López-Otín C, Rozman C, Campo E, López-Guillermo A, Martín-Subero JI.

Leukemia. 2014 Aug 25. doi: 10.1038/leu.2014.252. [Epub ahead of print]

PMID:
25151957
[PubMed - as supplied by publisher]
7.

ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.

Quirós PM, Español Y, Acín-Pérez R, Rodríguez F, Bárcena C, Watanabe K, Calvo E, Loureiro M, Fernández-García MS, Fueyo A, Vázquez J, Enríquez JA, López-Otín C.

Cell Rep. 2014 Jul 24;8(2):542-56. doi: 10.1016/j.celrep.2014.06.018. Epub 2014 Jul 10.

PMID:
25017063
[PubMed - in process]
Free Article
8.

MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.

Porlan E, Martí-Prado B, Morante-Redolat JM, Consiglio A, Delgado AC, Kypta R, López-Otín C, Kirstein M, Fariñas I.

Nat Cell Biol. 2014 Jul;16(7):629-38. doi: 10.1038/ncb2993. Epub 2014 Jun 22.

PMID:
24952463
[PubMed - indexed for MEDLINE]
9.

Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis.

Willemetz A, Lenoir A, Deschemin JC, Lopez-Otin C, Ramsay AJ, Vaulont S, Nicolas G.

Blood. 2014 Jul 17;124(3):441-4. doi: 10.1182/blood-2014-01-551150. Epub 2014 Jun 5.

PMID:
24904115
[PubMed - indexed for MEDLINE]
10.

Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome.

Bárcena C, Quesada V, De Sandre-Giovannoli A, Puente DA, Fernández-Toral J, Sigaudy S, Baban A, Lévy N, Velasco G, López-Otín C.

BMC Med Genet. 2014 May 2;15:51. doi: 10.1186/1471-2350-15-51.

PMID:
24886349
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome.

Martínez-Trillos A, Pinyol M, Navarro A, Aymerich M, Jares P, Juan M, Rozman M, Colomer D, Delgado J, Giné E, González-Díaz M, Hernández-Rivas JM, Colado E, Rayón C, Payer AR, Terol MJ, Navarro B, Quesada V, Puente XS, Rozman C, López-Otín C, Campo E, López-Guillermo A, Villamor N.

Blood. 2014 Jun 12;123(24):3790-6. doi: 10.1182/blood-2013-12-543306. Epub 2014 Apr 29.

PMID:
24782504
[PubMed - indexed for MEDLINE]
12.

The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells.

López-Guerra M, Xargay-Torrent S, Rosich L, Montraveta A, Roldán J, Matas-Céspedes A, Villamor N, Aymerich M, López-Otín C, Pérez-Galán P, Roué G, Campo E, Colomer D.

Leukemia. 2014 Apr 30. doi: 10.1038/leu.2014.143. [Epub ahead of print]

PMID:
24781018
[PubMed - as supplied by publisher]
13.

Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation.

González-Granado JM, Silvestre-Roig C, Rocha-Perugini V, Trigueros-Motos L, Cibrián D, Morlino G, Blanco-Berrocal M, Osorio FG, Freije JM, López-Otín C, Sánchez-Madrid F, Andrés V.

Sci Signal. 2014 Apr 22;7(322):ra37. doi: 10.1126/scisignal.2004872.

PMID:
24757177
[PubMed - in process]
14.

The prognostic impact of minimal residual disease in patients with chronic lymphocytic leukemia requiring first-line therapy.

Santacruz R, Villamor N, Aymerich M, Martínez-Trillos A, López C, Navarro A, Rozman M, Beà S, Royo C, Cazorla M, Colomer D, Giné E, Pinyol M, Puente XS, López-Otín C, Campo E, López-Guillermo A, Delgado J.

Haematologica. 2014 May;99(5):873-80. doi: 10.3324/haematol.2013.099796. Epub 2014 Apr 3.

PMID:
24700492
[PubMed - in process]
Free PMC Article
15.

POT1 loss-of-function variants predispose to familial melanoma.

Robles-Espinoza CD, Harland M, Ramsay AJ, Aoude LG, Quesada V, Ding Z, Pooley KA, Pritchard AL, Tiffen JC, Petljak M, Palmer JM, Symmons J, Johansson P, Stark MS, Gartside MG, Snowden H, Montgomery GW, Martin NG, Liu JZ, Choi J, Makowski M, Brown KM, Dunning AM, Keane TM, López-Otín C, Gruis NA, Hayward NK, Bishop DT, Newton-Bishop JA, Adams DJ.

Nat Genet. 2014 May;46(5):478-81. doi: 10.1038/ng.2947. Epub 2014 Mar 30.

PMID:
24686849
[PubMed - indexed for MEDLINE]
16.

OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury.

Xiao X, Hu Y, Quirós PM, Wei Q, López-Otín C, Dong Z.

Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1318-26. doi: 10.1152/ajprenal.00036.2014. Epub 2014 Mar 26.

PMID:
24671334
[PubMed - indexed for MEDLINE]
17.

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.

Llobet-Navas D, Rodríguez-Barrueco R, Castro V, Ugalde AP, Sumazin P, Jacob-Sendler D, Demircan B, Castillo-Martín M, Putcha P, Marshall N, Villagrasa P, Chan J, Sanchez-Garcia F, Pe'er D, Rabadán R, Iavarone A, Cordón-Cardó C, Califano A, López-Otín C, Ezhkova E, Silva JM.

Genes Dev. 2014 Apr 1;28(7):765-82. doi: 10.1101/gad.237404.114. Epub 2014 Mar 17.

PMID:
24636986
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulation of autophagy by cytosolic acetyl-coenzyme A.

Mariño G, Pietrocola F, Eisenberg T, Kong Y, Malik SA, Andryushkova A, Schroeder S, Pendl T, Harger A, Niso-Santano M, Zamzami N, Scoazec M, Durand S, Enot DP, Fernández ÁF, Martins I, Kepp O, Senovilla L, Bauvy C, Morselli E, Vacchelli E, Bennetzen M, Magnes C, Sinner F, Pieber T, López-Otín C, Maiuri MC, Codogno P, Andersen JS, Hill JA, Madeo F, Kroemer G.

Mol Cell. 2014 Mar 6;53(5):710-25. doi: 10.1016/j.molcel.2014.01.016. Epub 2014 Feb 20.

PMID:
24560926
[PubMed - indexed for MEDLINE]
19.

Progeria: a paradigm for translational medicine.

Gordon LB, Rothman FG, López-Otín C, Misteli T.

Cell. 2014 Jan 30;156(3):400-7. doi: 10.1016/j.cell.2013.12.028.

PMID:
24485450
[PubMed - indexed for MEDLINE]
20.

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.

Ferreira PG, Jares P, Rico D, Gómez-López G, Martínez-Trillos A, Villamor N, Ecker S, González-Pérez A, Knowles DG, Monlong J, Johnson R, Quesada V, Djebali S, Papasaikas P, López-Guerra M, Colomer D, Royo C, Cazorla M, Pinyol M, Clot G, Aymerich M, Rozman M, Kulis M, Tamborero D, Gouin A, Blanc J, Gut M, Gut I, Puente XS, Pisano DG, Martin-Subero JI, López-Bigas N, López-Guillermo A, Valencia A, López-Otín C, Campo E, Guigó R.

Genome Res. 2014 Feb;24(2):212-26. doi: 10.1101/gr.152132.112. Epub 2013 Nov 21.

PMID:
24265505
[PubMed - indexed for MEDLINE]
Free PMC Article

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