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Results: 1 to 20 of 45

1.

Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure.

Kim YK, Joung KH, Ryu MJ, Kim SJ, Kim H, Chung HK, Lee MH, Lee SE, Choi MJ, Chang JY, Hong HJ, Kim KS, Lee SH, Kweon GR, Kim H, Lee CH, Kim HJ, Shong M.

Diabetologia. 2015 Apr;58(4):771-80. doi: 10.1007/s00125-015-3506-y. Epub 2015 Feb 8.

PMID:
25660120
2.

Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans.

Lee MH, Lee JU, Joung KH, Kim YK, Ryu MJ, Lee SE, Kim SJ, Chung HK, Choi MJ, Chang JY, Lee SH, Kweon GR, Kim HJ, Kim KS, Kim SM, Jo YS, Park J, Cheng SY, Shong M.

Endocrinology. 2015 Mar;156(3):1181-93. doi: 10.1210/en.2014-1670. Epub 2015 Jan 2.

PMID:
25555091
3.

Docosahexaenoic acid prevents paraquat-induced reactive oxygen species production in dopaminergic neurons via enhancement of glutathione homeostasis.

Lee HJ, Han J, Jang Y, Kim SJ, Park JH, Seo KS, Jeong S, Shin S, Lim K, Heo JY, Kweon GR.

Biochem Biophys Res Commun. 2015 Jan 30;457(1):95-100. doi: 10.1016/j.bbrc.2014.12.085. Epub 2014 Dec 27.

PMID:
25545062
4.

The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.

Chung HK, Kim YK, Park JH, Ryu MJ, Chang JY, Hwang JH, Lee CH, Kim SH, Kim HJ, Kweon GR, Kim KS, Shong M.

Liver Int. 2015 Apr;35(4):1341-53. doi: 10.1111/liv.12741. Epub 2015 Jan 10.

PMID:
25443620
5.

Docosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin-proteasome system.

Jing K, Shin S, Jeong S, Kim S, Song KS, Park JH, Heo JY, Seo KS, Park SK, Kweon GR, Wu T, Park JI, Lim K.

Cell Death Dis. 2014 Nov 13;5:e1524. doi: 10.1038/cddis.2014.477.

6.

Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells.

Jeong S, Jing K, Kim N, Shin S, Kim S, Song KS, Heo JY, Park JH, Seo KS, Han J, Wu T, Kweon GR, Park SK, Park JI, Lim K.

BMC Cancer. 2014 Jul 3;14:481. doi: 10.1186/1471-2407-14-481.

7.

SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation.

Seo KS, Park JH, Heo JY, Jing K, Han J, Min KN, Kim C, Koh GY, Lim K, Kang GY, Uee Lee J, Yim YH, Shong M, Kwak TH, Kweon GR.

Oncogene. 2015 Mar 12;34(11):1354-62. doi: 10.1038/onc.2014.76. Epub 2014 Mar 31.

PMID:
24681946
8.

The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy.

Yang CS, Kim JJ, Lee HM, Jin HS, Lee SH, Park JH, Kim SJ, Kim JM, Han YM, Lee MS, Kweon GR, Shong M, Jo EK.

Autophagy. 2014 May;10(5):785-802. doi: 10.4161/auto.28072. Epub 2014 Feb 25.

PMID:
24598403
9.

PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells.

Seo KS, Kim JS, Park JH, Song KS, Yun EJ, Park JI, Kweon GR, Yoon WH, Lim K, Hwang BD.

BMC Cancer. 2014 Jan 22;14:36. doi: 10.1186/1471-2407-14-36.

10.

The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53.

Shin S, Jing K, Jeong S, Kim N, Song KS, Heo JY, Park JH, Seo KS, Han J, Park JI, Kweon GR, Park SK, Wu T, Hwang BD, Lim K.

Biomed Res Int. 2013;2013:568671. doi: 10.1155/2013/568671. Epub 2013 Jun 10.

11.

Apicularen A acetate induces cell death via AIF translocation and disrupts the microtubule network by down-regulating tubulin in HM7 human colon cancer cells.

Seo KS, Kim H, Hong TH, Kim JS, Song KS, Yun EJ, Park JH, Jung YH, Park JI, Kweon GR, Yoon WH, Lim K, Hwang BD.

Biochem Biophys Res Commun. 2013 May 10;434(3):634-40. doi: 10.1016/j.bbrc.2013.03.133. Epub 2013 Apr 10.

PMID:
23583412
12.

Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice.

Ryu MJ, Kim SJ, Kim YK, Choi MJ, Tadi S, Lee MH, Lee SE, Chung HK, Jung SB, Kim HJ, Jo YS, Kim KS, Lee SH, Kim JM, Kweon GR, Park KC, Lee JU, Kong YY, Lee CH, Chung J, Shong M.

PLoS Genet. 2013;9(3):e1003356. doi: 10.1371/journal.pgen.1003356. Epub 2013 Mar 14.

13.

Mitochondrial oxidative phosphorylation reserve is required for hormone- and PPARγ agonist-induced adipogenesis.

Ryu MJ, Kim SJ, Choi MJ, Kim YK, Lee MH, Lee SE, Chung HK, Jung SB, Kim HJ, Kim KS, Jo YS, Kweon GR, Lee CH, Shong M.

Mol Cells. 2013 Feb;35(2):134-41. doi: 10.1007/s10059-012-2257-1. Epub 2013 Feb 20.

14.

Dexamethasone Induces FcγRIIb Expression in RBL-2H3 Cells.

Silwal P, Lee MN, Lee CJ, Hong JH, Namgung U, Lee ZW, Kim J, Lim K, Kweon GR, Park JI, Park SK.

Korean J Physiol Pharmacol. 2012 Dec;16(6):393-8. doi: 10.4196/kjpp.2012.16.6.393. Epub 2012 Dec 10.

15.

Phosphoenolpyruvate carboxykinase and glucose-6-phosphatase are required for steroidogenesis in testicular Leydig cells.

Ahn SW, Gang GT, Tadi S, Nedumaran B, Kim YD, Park JH, Kweon GR, Koo SH, Lee K, Ahn RS, Yim YH, Lee CH, Harris RA, Choi HS.

J Biol Chem. 2012 Dec 7;287(50):41875-87. doi: 10.1074/jbc.M112.421552. Epub 2012 Oct 16.

16.

CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.

Kim SJ, Kwon MC, Ryu MJ, Chung HK, Tadi S, Kim YK, Kim JM, Lee SH, Park JH, Kweon GR, Ryu SW, Jo YS, Lee CH, Hatakeyama H, Goto Y, Yim YH, Chung J, Kong YY, Shong M.

Cell Metab. 2012 Aug 8;16(2):274-83. doi: 10.1016/j.cmet.2012.06.012. Epub 2012 Jul 19.

17.

DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly.

Heo JY, Park JH, Kim SJ, Seo KS, Han JS, Lee SH, Kim JM, Park JI, Park SK, Lim K, Hwang BD, Shong M, Kweon GR.

PLoS One. 2012;7(3):e32629. doi: 10.1371/journal.pone.0032629. Epub 2012 Mar 5.

18.

Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase.

Kim YH, Hwang JH, Noh JR, Gang GT, Tadi S, Yim YH, Jeoung NH, Kwak TH, Lee SH, Kweon GR, Kim JM, Shong M, Lee IK, Lee CH.

Free Radic Biol Med. 2012 Mar 1;52(5):880-8. doi: 10.1016/j.freeradbiomed.2011.12.007. Epub 2011 Dec 20.

PMID:
22227174
19.

Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling.

Song KS, Jing K, Kim JS, Yun EJ, Shin S, Seo KS, Park JH, Heo JY, Kang JX, Suh KS, Wu T, Park JI, Kweon GR, Yoon WH, Hwang BD, Lim K.

Pancreatology. 2011;11(6):574-84. doi: 10.1159/000334468. Epub 2011 Dec 31.

PMID:
22213040
20.

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53.

Jing K, Song KS, Shin S, Kim N, Jeong S, Oh HR, Park JH, Seo KS, Heo JY, Han J, Park JI, Han C, Wu T, Kweon GR, Park SK, Yoon WH, Hwang BD, Lim K.

Autophagy. 2011 Nov;7(11):1348-58. doi: 10.4161/auto.7.11.16658. Epub 2011 Nov 1.

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