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Items: 1 to 20 of 83

1.

Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.

Kouznetsova E, Kanno T, Karlberg T, Thorsell AG, Wisniewska M, Kursula P, Sjögren C, Schüler H.

Structure. 2016 Apr 21. pii: S0969-2126(16)30032-6. doi: 10.1016/j.str.2016.03.021. [Epub ahead of print]

PMID:
27112597
3.

Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.

Raasakka A, Myllykoski M, Laulumaa S, Lehtimäki M, Härtlein M, Moulin M, Kursula I, Kursula P.

Sci Rep. 2015 Nov 13;5:16520. doi: 10.1038/srep16520.

4.

Production, crystallization and neutron diffraction of fully deuterated human myelin peripheral membrane protein P2.

Laulumaa S, Blakeley MP, Raasakka A, Moulin M, Härtlein M, Kursula P.

Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1391-5. doi: 10.1107/S2053230X15017902. Epub 2015 Oct 23.

PMID:
26527266
5.

Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

Myllykoski M, Seidel L, Muruganandam G, Raasakka A, Torda AE, Kursula P.

Brain Res. 2015 Sep 11. pii: S0006-8993(15)00701-5. doi: 10.1016/j.brainres.2015.09.004. [Epub ahead of print] Review.

PMID:
26367445
6.

Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant.

Laulumaa S, Nieminen T, Lehtimäki M, Aggarwal S, Simons M, Koza MM, Vattulainen I, Kursula P, Natali F.

PLoS One. 2015 Jun 11;10(6):e0128954. doi: 10.1371/journal.pone.0128954. eCollection 2015.

7.

Two independently folding units of Plasmodium profilin suggest evolution via gene fusion.

Bhargav SP, Vahokoski J, Kallio JP, Torda AE, Kursula P, Kursula I.

Cell Mol Life Sci. 2015 Nov;72(21):4193-203. doi: 10.1007/s00018-015-1932-0. Epub 2015 May 27.

PMID:
26012696
8.

The N-terminal cytoplasmic domain of neuregulin 1 type III is intrinsically disordered.

Chukhlieb M, Raasakka A, Ruskamo S, Kursula P.

Amino Acids. 2015 Aug;47(8):1567-77. doi: 10.1007/s00726-015-1998-x. Epub 2015 May 6.

PMID:
25944317
9.

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.

Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, Desnuelle C, Soriani MH, Dorst J, Graf E, Nordström U, Feiler MS, Putz S, Boeckers TM, Meyer T, Winkler AS, Winkelman J, de Carvalho M, Thal DR, Otto M, Brännström T, Volk AE, Kursula P, Danzer KM, Lichtner P, Dikic I, Meitinger T, Ludolph AC, Strom TM, Andersen PM, Weishaupt JH.

Nat Neurosci. 2015 May;18(5):631-6. doi: 10.1038/nn.4000. Epub 2015 Mar 24.

PMID:
25803835
10.

Human adenosine A2A receptor binds calmodulin with high affinity in a calcium-dependent manner.

Piirainen H, Hellman M, Tossavainen H, Permi P, Kursula P, Jaakola VP.

Biophys J. 2015 Feb 17;108(4):903-17. doi: 10.1016/j.bpj.2014.12.036.

11.

The olfactomedin domain from gliomedin is a β-propeller with unique structural properties.

Han H, Kursula P.

J Biol Chem. 2015 Feb 6;290(6):3612-21. doi: 10.1074/jbc.M114.627547. Epub 2014 Dec 17.

12.

Human Δ³,Δ²-enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.

Onwukwe GU, Kursula P, Koski MK, Schmitz W, Wierenga RK.

FEBS J. 2015 Feb;282(4):746-68. doi: 10.1111/febs.13179. Epub 2015 Jan 14.

13.

Influence of myelin proteins on the structure and dynamics of a model membrane with emphasis on the low temperature regime.

Knoll W, Peters J, Kursula P, Gerelli Y, Natali F.

J Chem Phys. 2014 Nov 28;141(20):205101. doi: 10.1063/1.4901738.

PMID:
25429962
14.

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the extracellular olfactomedin domain of gliomedin.

Han H, Kursula P.

Acta Crystallogr F Struct Biol Commun. 2014 Nov;70(Pt 11):1536-9. doi: 10.1107/S2053230X14020305. Epub 2014 Oct 25.

PMID:
25372825
15.

The many structural faces of calmodulin: a multitasking molecular jackknife.

Kursula P.

Amino Acids. 2014 Oct;46(10):2295-304. doi: 10.1007/s00726-014-1795-y. Epub 2014 Jul 9. Review.

PMID:
25005783
16.

A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells.

Zenker J, Stettner M, Ruskamo S, Domènech-Estévez E, Baloui H, Médard JJ, Verheijen MH, Brouwers JF, Kursula P, Kieseier BC, Chrast R.

Glia. 2014 Sep;62(9):1502-12. doi: 10.1002/glia.22696. Epub 2014 May 21.

PMID:
24849898
17.

The myelin membrane-associated enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase: on a highway to structure and function.

Raasakka A, Kursula P.

Neurosci Bull. 2014 Dec;30(6):956-66. doi: 10.1007/s12264-013-1437-5. Epub 2014 May 7. Review.

PMID:
24807122
18.

Periaxin and AHNAK nucleoprotein 2 form intertwined homodimers through domain swapping.

Han H, Kursula P.

J Biol Chem. 2014 May 16;289(20):14121-31. doi: 10.1074/jbc.M114.554816. Epub 2014 Mar 27.

19.

Structural and dynamical properties of reconstituted myelin sheaths in the presence of myelin proteins MBP and P2 studied by neutron scattering.

Knoll W, Peters J, Kursula P, Gerelli Y, Ollivier J, Demé B, Telling M, Kemner E, Natali F.

Soft Matter. 2014 Jan 21;10(3):519-29. doi: 10.1039/c3sm51393a.

PMID:
24651633
20.

Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2.

Ruskamo S, Yadav RP, Sharma S, Lehtimäki M, Laulumaa S, Aggarwal S, Simons M, Bürck J, Ulrich AS, Juffer AH, Kursula I, Kursula P.

Acta Crystallogr D Biol Crystallogr. 2014 Jan;70(Pt 1):165-76. doi: 10.1107/S1399004713027910. Epub 2013 Dec 31.

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