Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 99

1.

Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors.

Do K, Speranza G, Chang LC, Polley EC, Bishop R, Zhu W, Trepel JB, Lee S, Lee MJ, Kinders RJ, Phillips L, Collins J, Lyons J, Jeong W, Antony R, Chen AP, Neckers L, Doroshow JH, Kummar S.

Invest New Drugs. 2015 Jun 18. [Epub ahead of print]

PMID:
26082332
2.

Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors.

Do K, Wilsker D, Ji J, Zlott J, Freshwater T, Kinders RJ, Collins J, Chen AP, Doroshow JH, Kummar S.

J Clin Oncol. 2015 May 11. pii: JCO.2014.60.4009. [Epub ahead of print]

PMID:
25964244
3.

A Phase II Study of Sorafenib Combined With Cetuximab in EGFR-Expressing, KRAS-Mutated Metastatic Colorectal Cancer.

Do K, Cao L, Kang Z, Turkbey B, Lindenberg ML, Larkins E, Holkova B, Steinberg SM, Raffeld M, Peer CJ, Figg WD, Eugeni M, Jacobs P, Choyke P, Wright JJ, Doroshow JH, Kummar S.

Clin Colorectal Cancer. 2015 Mar 7. pii: S1533-0028(15)00036-5. doi: 10.1016/j.clcc.2015.02.007. [Epub ahead of print]

PMID:
25861837
4.

GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials.

Zhao Y, Polley EC, Li MC, Lih CJ, Palmisano A, Sims DJ, Rubinstein LV, Conley BA, Chen AP, Williams PM, Kummar S, Doroshow JH, Simon RM.

Cancer Inform. 2015 Mar 19;14(Suppl 2):45-55. doi: 10.4137/CIN.S17282. eCollection 2015. Review.

5.

Application of molecular profiling in clinical trials for advanced metastatic cancers.

Kummar S, Williams PM, Lih CJ, Polley EC, Chen AP, Rubinstein LV, Zhao Y, Simon RM, Conley BA, Doroshow JH.

J Natl Cancer Inst. 2015 Feb 6;107(4). pii: djv003. doi: 10.1093/jnci/djv003. Print 2015 Apr.

PMID:
25663694
6.

Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer.

Do K, Speranza G, Bishop R, Khin S, Rubinstein L, Kinders RJ, Datiles M, Eugeni M, Lam MH, Doyle LA, Doroshow JH, Kummar S.

Invest New Drugs. 2015 Jun;33(3):720-8. doi: 10.1007/s10637-015-0212-z. Epub 2015 Feb 1.

PMID:
25637165
7.

Randomized Trial of Oral Cyclophosphamide and Veliparib in High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers, or BRCA-Mutant Ovarian Cancer.

Kummar S, Oza AM, Fleming GF, Sullivan DM, Gandara DR, Naughton MJ, Villalona-Calero MA, Morgan RJ Jr, Szabo PM, Youn A, Chen AP, Ji J, Allen DE, Lih CJ, Mehaffey MG, Walsh WD, McGregor PM 3rd, Steinberg SM, Williams PM, Kinders RJ, Conley BA, Simon RM, Doroshow JH.

Clin Cancer Res. 2015 Apr 1;21(7):1574-82. doi: 10.1158/1078-0432.CCR-14-2565. Epub 2015 Jan 14.

PMID:
25589624
8.

A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine, administered with tetrahydrouridine.

Newman EM, Morgan RJ, Kummar S, Beumer JH, Blanchard MS, Ruel C, El-Khoueiry AB, Carroll MI, Hou JM, Li C, Lenz HJ, Eiseman JL, Doroshow JH.

Cancer Chemother Pharmacol. 2015 Mar;75(3):537-46. doi: 10.1007/s00280-014-2674-7. Epub 2015 Jan 8.

PMID:
25567350
9.

New, tolerable γ-secretase inhibitor takes desmoid down a notch.

Hughes DP, Kummar S, Lazar AJ.

Clin Cancer Res. 2015 Jan 1;21(1):7-9. doi: 10.1158/1078-0432.CCR-14-1660. Epub 2014 Oct 21.

PMID:
25336699
10.

Translational research in oncology--10 years of progress and future prospects.

Doroshow JH, Kummar S.

Nat Rev Clin Oncol. 2014 Nov;11(11):649-62. doi: 10.1038/nrclinonc.2014.158. Epub 2014 Oct 7.

PMID:
25286976
11.

Paraneoplastic neurologic manifestations of malignancies. Foreword.

Kummar S.

Curr Probl Cancer. 2014 Jul-Aug;38(4):114. doi: 10.1016/j.currproblcancer.2014.08.001. Epub 2014 Aug 12. No abstract available.

PMID:
25239544
12.

Validation of a hypoxia-inducible factor-1 alpha specimen collection procedure and quantitative enzyme-linked immunosorbent assay in solid tumor tissues.

Park SR, Kinders RJ, Khin S, Hollingshead M, Antony S, Parchment RE, Tomaszewski JE, Kummar S, Doroshow JH.

Anal Biochem. 2014 Aug 15;459:1-11. doi: 10.1016/j.ab.2014.04.025. Epub 2014 May 4.

PMID:
24799347
13.

Cabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma.

Yavuz S, Apolo AB, Kummar S, del Rivero J, Madan RA, Shawker T, Reynolds J, Celi FS.

Thyroid. 2014 Aug;24(8):1223-31. doi: 10.1089/thy.2013.0621. Epub 2014 Jun 5.

PMID:
24724719
14.

These tumors can be associated with known genetic syndromes, such as the von Hippel-Lindau or multiple endocrine neoplasia 2 syndromes, or they can arise sporadically. Foreword.

Kummar S.

Curr Probl Cancer. 2014 Jan-Feb;38(1):6. doi: 10.1016/j.currproblcancer.2014.02.001. Epub 2014 Feb 17. No abstract available.

PMID:
24636753
15.

Pilot trial of EZN-2968, an antisense oligonucleotide inhibitor of hypoxia-inducible factor-1 alpha (HIF-1α), in patients with refractory solid tumors.

Jeong W, Rapisarda A, Park SR, Kinders RJ, Chen A, Melillo G, Turkbey B, Steinberg SM, Choyke P, Doroshow JH, Kummar S.

Cancer Chemother Pharmacol. 2014 Feb;73(2):343-8. doi: 10.1007/s00280-013-2362-z. Epub 2013 Nov 30.

PMID:
24292632
16.

Weekly EZN-2208 (PEGylated SN-38) in combination with bevacizumab in patients with refractory solid tumors.

Jeong W, Park SR, Rapisarda A, Fer N, Kinders RJ, Chen A, Melillo G, Turkbey B, Steinberg SM, Choyke P, Doroshow JH, Kummar S.

Invest New Drugs. 2014 Apr;32(2):340-6. doi: 10.1007/s10637-013-0048-3. Epub 2013 Nov 16.

PMID:
24242862
17.

Current Problems in Cancer. Bone tumors in children and young adults. Foreword.

Kummar S.

Curr Probl Cancer. 2013 Jul-Aug;37(4):159. doi: 10.1016/j.currproblcancer.2013.07.001. No abstract available.

PMID:
24238579
18.

Wee1 kinase as a target for cancer therapy.

Do K, Doroshow JH, Kummar S.

Cell Cycle. 2013 Oct 1;12(19):3159-64. doi: 10.4161/cc.26062. Epub 2013 Aug 26. Review.

19.

United States Food and Drug Administration approved oral kinase inhibitors for the treatment of malignancies.

Jeong W, Doroshow JH, Kummar S.

Curr Probl Cancer. 2013 May-Jun;37(3):110-44. doi: 10.1016/j.currproblcancer.2013.06.001. Review. No abstract available.

20.

Pharmacogenetically driven patient selection for a first-in-human phase I trial of batracylin in patients with advanced solid tumors and lymphomas.

Kummar S, Gutierrez ME, Anderson LW, Klecker RW Jr, Chen A, Murgo AJ, Doroshow JH, Collins JM.

Cancer Chemother Pharmacol. 2013 Oct;72(4):917-23. doi: 10.1007/s00280-013-2244-4. Epub 2013 Aug 3.

PMID:
23912694
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk