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Results: 1 to 20 of 161

1.

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, Pathak J, Bielinski SJ, Carrell DS, Crosslin DR, Ledbetter DH, Carey DJ, Tromp G, Williams MS, Larson EB, Jarvik GP, Peissig PL, Brilliant MH, McCarty CA, Chute CG, Kullo IJ, Bottinger E, Chisholm R, Smith ME, Roden DM, Denny JC.

Front Genet. 2014 Aug 5;5:250. doi: 10.3389/fgene.2014.00250. eCollection 2014.

PMID:
25177340
[PubMed]
Free PMC Article
2.

A Summary and Critical Assessment of the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Disease Risk in Adults: Filling the Gaps.

Lopez-Jimenez F, Simha V, Thomas RJ, Allison TG, Basu A, Fernandes R, Hurst RT, Kopecky SL, Kullo IJ, Mulvagh SL, Thompson WG, Trejo-Gutierrez JF, Wright RS.

Mayo Clin Proc. 2014 Sep;89(9):1257-1278. doi: 10.1016/j.mayocp.2014.06.016. Epub 2014 Aug 12. Review.

PMID:
25131697
[PubMed - as supplied by publisher]
3.

A Perspective on the New American College of Cardiology/American Heart Association Guidelines for Cardiovascular Risk Assessment.

Kullo IJ, Trejo-Gutierrez JF, Lopez-Jimenez F, Thomas RJ, Allison TG, Mulvagh SL, Arruda-Olson AM, Hayes SN, Pollak AW, Kopecky SL, Hurst RT.

Mayo Clin Proc. 2014 Sep;89(9):1244-1256. doi: 10.1016/j.mayocp.2014.06.018. Epub 2014 Aug 12. Review.

PMID:
25131696
[PubMed - as supplied by publisher]
4.

Clinical Correlates of Autosomal Chromosomal Abnormalities in an Electronic Medical Record-Linked Genome-Wide Association Study: A Case Series.

Jouni H, Shameer K, Asmann YW, Hazin R, de Andrade M, Kullo IJ.

J Investig Med. 2013 Oct;1(4). pii: 2324709613508932.

PMID:
25125939
[PubMed]
Free PMC Article
5.

Whole Exome Sequencing Implicates an INO80D Mutation in a Syndrome of Aortic Hypoplasia, Premature Atherosclerosis, and Arterial Stiffness.

Shameer K, Klee EW, Dalenberg AK, Kullo IJ.

Circ Cardiovasc Genet. 2014 Aug 13. pii: CIRCGENETICS.113.000233. [Epub ahead of print]

PMID:
25122053
[PubMed - as supplied by publisher]
6.

Family history as a risk factor for peripheral arterial disease.

Khaleghi M, Isseh IN, Bailey KR, Kullo IJ.

Am J Cardiol. 2014 Sep 15;114(6):928-32. doi: 10.1016/j.amjcard.2014.06.029. Epub 2014 Jul 2.

PMID:
25107577
[PubMed - in process]
7.

Predicting long-term cardiovascular risk using the mayo clinic cardiovascular risk score in a referral population.

Dhoble A, Lahr BD, Allison TG, Bailey KR, Thomas RJ, Lopez-Jimenez F, Kullo IJ, Gupta B, Kopecky SL.

Am J Cardiol. 2014 Sep 1;114(5):704-10. doi: 10.1016/j.amjcard.2014.05.061. Epub 2014 Jun 19.

PMID:
25052544
[PubMed - in process]
8.

The ATXN2-SH2B3 locus is associated with peripheral arterial disease: an electronic medical record-based genome-wide association study.

Kullo IJ, Shameer K, Jouni H, Lesnick TG, Pathak J, Chute CG, de Andrade M.

Front Genet. 2014 Jun 25;5:166. doi: 10.3389/fgene.2014.00166. eCollection 2014.

PMID:
25009551
[PubMed]
Free PMC Article
9.

Family history as a risk factor for carotid artery stenosis.

Khaleghi M, Isseh IN, Jouni H, Sohn S, Bailey KR, Kullo IJ.

Stroke. 2014 Aug;45(8):2252-6. doi: 10.1161/STROKEAHA.114.006245. Epub 2014 Jul 8.

PMID:
25005442
[PubMed - in process]
10.

eMERGEing progress in genomics-the first seven years.

Crawford DC, Crosslin DR, Tromp G, Kullo IJ, Kuivaniemi H, Hayes MG, Denny JC, Bush WS, Haines JL, Roden DM, McCarty CA, Jarvik GP, Ritchie MD.

Front Genet. 2014 Jun 17;5:184. doi: 10.3389/fgene.2014.00184. eCollection 2014. Review.

PMID:
24987407
[PubMed]
Free PMC Article
11.

Relationship between measures of central and general adiposity with aortic stiffness in the general population.

Wohlfahrt P, Somers VK, Cifkova R, Filipovsky J, Seidlerova J, Krajcoviechova A, Sochor O, Kullo IJ, Lopez-Jimenez F.

Atherosclerosis. 2014 Aug;235(2):625-31. doi: 10.1016/j.atherosclerosis.2014.05.958. Epub 2014 Jun 9.

PMID:
24968316
[PubMed - in process]
12.

Design and Anticipated Outcomes of the eMERGE-PGx Project: A Multicenter Pilot for Preemptive Pharmacogenomics in Electronic Health Record Systems.

Rasmussen-Torvik LJ, Stallings SC, Gordon AS, Almoguera B, Basford MA, Bielinski SJ, Brautbar A, Brilliant MH, Carrell DS, Connolly JJ, Crosslin DR, Doheny KF, Gallego CJ, Gottesman O, Kim DS, Leppig KA, Li R, Lin S, Manzi S, Mejia AR, Pacheco JA, Pan V, Pathak J, Perry CL, Peterson JF, Prows CA, Ralston J, Rasmussen LV, Ritchie MD, Sadhasivam S, Scott SA, Smith M, Vega A, Vinks AA, Volpi S, Wolf WA, Bottinger E, Chisholm RL, Chute CG, Haines JL, Harley JB, Keating B, Holm IA, Kullo IJ, Jarvik GP, Larson EB, Manolio T, McCarty CA, Nickerson DA, Scherer SE, Williams MS, Roden DM, Denny JC.

Clin Pharmacol Ther. 2014 Jun 24. doi: 10.1038/clpt.2014.137. [Epub ahead of print]

PMID:
24960519
[PubMed - as supplied by publisher]
13.

Arterial stiffness is associated with increase in blood pressure over time in treated hypertensives.

Coutinho T, Bailey KR, Turner ST, Kullo IJ.

J Am Soc Hypertens. 2014 Jun;8(6):414-21. doi: 10.1016/j.jash.2014.03.330. Epub 2014 Apr 4.

PMID:
24952654
[PubMed - in process]
14.

The association of 9p21-3 locus with coronary atherosclerosis: a systematic review and meta-analysis.

Munir MS, Wang Z, Alahdab F, Steffen MW, Erwin PJ, Kullo IJ, Murad MH.

BMC Med Genet. 2014 Jun 6;15:66. doi: 10.1186/1471-2350-15-66. Review.

PMID:
24906238
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Return of genomic results to research participants: the floor, the ceiling, and the choices in between.

Jarvik GP, Amendola LM, Berg JS, Brothers K, Clayton EW, Chung W, Evans BJ, Evans JP, Fullerton SM, Gallego CJ, Garrison NA, Gray SW, Holm IA, Kullo IJ, Lehmann LS, McCarty C, Prows CA, Rehm HL, Sharp RR, Salama J, Sanderson S, Van Driest SL, Williams MS, Wolf SM, Wolf WA; eMERGE Act-ROR Committee and CERC Committee; CSER Act-ROR Working Group, Burke W.

Am J Hum Genet. 2014 Jun 5;94(6):818-26. doi: 10.1016/j.ajhg.2014.04.009. Epub 2014 May 8.

PMID:
24814192
[PubMed - indexed for MEDLINE]
16.

Return of results in the genomic medicine projects of the eMERGE network.

Kullo IJ, Haddad R, Prows CA, Holm I, Sanderson SC, Garrison NA, Sharp RR, Smith ME, Kuivaniemi H, Bottinger EP, Connolly JJ, Keating BJ, McCarty CA, Williams MS, Jarvik GP.

Front Genet. 2014 Mar 26;5:50. doi: 10.3389/fgene.2014.00050. eCollection 2014.

PMID:
24723935
[PubMed]
Free PMC Article
17.

Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.

Bielinski SJ, Olson JE, Pathak J, Weinshilboum RM, Wang L, Lyke KJ, Ryu E, Targonski PV, Van Norstrand MD, Hathcock MA, Takahashi PY, McCormick JB, Johnson KJ, Maschke KJ, Rohrer Vitek CR, Ellingson MS, Wieben ED, Farrugia G, Morrisette JA, Kruckeberg KJ, Bruflat JK, Peterson LM, Blommel JH, Skierka JM, Ferber MJ, Black JL, Baudhuin LM, Klee EW, Ross JL, Veldhuizen TL, Schultz CG, Caraballo PJ, Freimuth RR, Chute CG, Kullo IJ.

Mayo Clin Proc. 2014 Jan;89(1):25-33. doi: 10.1016/j.mayocp.2013.10.021.

PMID:
24388019
[PubMed - indexed for MEDLINE]
18.

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.

Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM.

PLoS One. 2013 Dec 12;8(12):e81503. doi: 10.1371/journal.pone.0081503. eCollection 2013.

PMID:
24349080
[PubMed - in process]
Free PMC Article
19.

Identifying Abdominal Aortic Aneurysm Cases and Controls using Natural Language Processing of Radiology Reports.

Sohn S, Ye Z, Liu H, Chute CG, Kullo IJ.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:249-53. eCollection 2013.

PMID:
24303276
[PubMed]
Free PMC Article
20.

An information extraction framework for cohort identification using electronic health records.

Liu H, Bielinski SJ, Sohn S, Murphy S, Wagholikar KB, Jonnalagadda SR, Ravikumar KE, Wu ST, Kullo IJ, Chute CG.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:149-53. eCollection 2013.

PMID:
24303255
[PubMed]
Free PMC Article

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