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Items: 1 to 20 of 46


Monitoring of treatment responses and clonal evolution of tumor cells by circulating tumor DNA of heterogeneous mutant EGFR genes in lung cancer.

Imamura F, Uchida J, Kukita Y, Kumagai T, Nishino K, Inoue T, Kimura M, Oba S, Kato K.

Lung Cancer. 2016 Apr;94:68-73. doi: 10.1016/j.lungcan.2016.01.023. Epub 2016 Feb 2.


Dynamics of circulating tumor DNA represented by the activating and resistant mutations in epidermal growth factor receptor tyrosine kinase inhibitor treatment.

Uchida J, Imamura F, Kukita Y, Oba S, Kumagai T, Nishino K, Inoue T, Kimura M, Kato K.

Cancer Sci. 2016 Mar;107(3):353-8. doi: 10.1111/cas.12860. Epub 2016 Feb 18.


A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes.

Tahira T, Yahara K, Kukita Y, Higasa K, Kato K, Wake N, Hayashi K.

Genom Data. 2014 Apr 24;2:55-9. doi: 10.1016/j.gdata.2014.04.006. eCollection 2014 Dec.


Diagnostic Accuracy of Noninvasive Genotyping of EGFR in Lung Cancer Patients by Deep Sequencing of Plasma Cell-Free DNA.

Uchida J, Kato K, Kukita Y, Kumagai T, Nishino K, Daga H, Nagatomo I, Inoue T, Kimura M, Oba S, Ito Y, Takeda K, Imamura F.

Clin Chem. 2015 Sep;61(9):1191-6. doi: 10.1373/clinchem.2015.241414. Epub 2015 Jul 23.


High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients.

Kukita Y, Matoba R, Uchida J, Hamakawa T, Doki Y, Imamura F, Kato K.

DNA Res. 2015 Aug;22(4):269-77. doi: 10.1093/dnares/dsv010. Epub 2015 Jun 29.


Analysis of ERBB ligand-induced resistance mechanism to crizotinib by primary culture of lung adenocarcinoma with EML4-ALK fusion gene.

Kimura M, Endo H, Inoue T, Nishino K, Uchida J, Kumagai T, Kukita Y, Kato K, Imamura F, Inoue M.

J Thorac Oncol. 2015 Mar;10(3):527-30. doi: 10.1097/JTO.0000000000000381.


Monitoring gastric cancer progression with circulating tumour DNA.

Hamakawa T, Kukita Y, Kurokawa Y, Miyazaki Y, Takahashi T, Yamasaki M, Miyata H, Nakajima K, Taniguchi K, Takiguchi S, Mori M, Doki Y, Kato K.

Br J Cancer. 2015 Jan 20;112(2):352-6. doi: 10.1038/bjc.2014.609. Epub 2014 Dec 9.


Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region.

Kanemoto M, Shirahata M, Nakauma A, Nakanishi K, Taniguchi K, Kukita Y, Arakawa Y, Miyamoto S, Kato K.

BMC Cancer. 2014 Aug 30;14:641. doi: 10.1186/1471-2407-14-641.


Quantitative identification of mutant alleles derived from lung cancer in plasma cell-free DNA via anomaly detection using deep sequencing data.

Kukita Y, Uchida J, Oba S, Nishino K, Kumagai T, Taniguchi K, Okuyama T, Imamura F, Kato K.

PLoS One. 2013 Nov 21;8(11):e81468. doi: 10.1371/journal.pone.0081468. eCollection 2013.


Conversion of a molecular classifier obtained by gene expression profiling into a classifier based on real-time PCR: a prognosis predictor for gliomas.

Kawarazaki S, Taniguchi K, Shirahata M, Kukita Y, Kanemoto M, Mikuni N, Hashimoto N, Miyamoto S, Takahashi JA, Kato K.

BMC Med Genomics. 2010 Nov 10;3:52. doi: 10.1186/1755-8794-3-52.


A definitive haplotype map as determined by genotyping duplicated haploid genomes finds a predominant haplotype preference at copy-number variation events.

Kukita Y, Yahara K, Tahira T, Higasa K, Sonoda M, Yamamoto K, Kato K, Wake N, Hayashi K.

Am J Hum Genet. 2010 Jun 11;86(6):918-28. doi: 10.1016/j.ajhg.2010.05.003. Epub 2010 May 27.


Fluid epitaxialization effect on velocity dependence of dynamic contact angle in molecular scale.

Ito T, Hirata Y, Kukita Y.

J Chem Phys. 2010 Feb 7;132(5):054702. doi: 10.1063/1.3294879.


Impact of group IVA cytosolic phospholipase A2 gene polymorphisms on phenotypic features of patients with familial adenomatous polyposis.

Umeno J, Matsumoto T, Esaki M, Kukita Y, Tahira T, Yanaru-Fujisawa R, Nakamura S, Arima H, Hirahashi M, Hayashi K, Iida M.

Int J Colorectal Dis. 2010 Mar;25(3):293-301. doi: 10.1007/s00384-009-0808-x. Epub 2009 Oct 1.


Estimation of SNP allele frequencies by SSCP analysis of pooled DNA.

Tahira T, Kukita Y, Higasa K, Okazaki Y, Yoshinaga A, Hayashi K.

Methods Mol Biol. 2009;578:193-207. doi: 10.1007/978-1-60327-411-1_12.


Evaluation of haplotype inference using definitive haplotype data obtained from complete hydatidiform moles, and its significance for the analyses of positively selected regions.

Higasa K, Kukita Y, Kato K, Wake N, Tahira T, Hayashi K.

PLoS Genet. 2009 May;5(5):e1000468. doi: 10.1371/journal.pgen.1000468. Epub 2009 May 8.


Prevalence of copy-number neutral LOH in glioblastomas revealed by genomewide analysis of laser-microdissected tissues.

Kuga D, Mizoguchi M, Guan Y, Hata N, Yoshimoto K, Shono T, Suzuki SO, Kukita Y, Tahira T, Nagata S, Sasaki T, Hayashi K.

Neuro Oncol. 2008 Dec;10(6):995-1003. doi: 10.1215/15228517-2008-064. Epub 2008 Aug 12.


Primary total hip arthroplasty with Asian-type AML total hip prosthesis: follow-up for more than 10 years.

Kaya M, Nagoya S, Sasaki M, Kukita Y, Yamashita T.

J Orthop Sci. 2008 Jul;13(4):324-7. doi: 10.1007/s00776-008-1236-4. Epub 2008 Aug 13.


Narrowing of the regions of allelic losses of chromosome 1p36 in meningioma tissues by an improved SSCP analysis.

Guan Y, Hata N, Kuga D, Yoshimoto K, Mizoguchi M, Shono T, Suzuki SO, Tahira T, Kukita Y, Higasa K, Yokoyama N, Nagata S, Iwaki T, Sasaki T, Hayashi K.

Int J Cancer. 2008 Apr 15;122(8):1820-6.


D-HaploDB: a database of definitive haplotypes determined by genotyping complete hydatidiform mole samples.

Higasa K, Miyatake K, Kukita Y, Tahira T, Hayashi K.

Nucleic Acids Res. 2007 Jan;35(Database issue):D685-9. Epub 2006 Dec 13.


Impact of Phospholipase A2 group IIa gene polymorphism on phenotypic features of patients with familial adenomatous polyposis.

Yanaru-Fujisawa R, Matsumoto T, Kukita Y, Nakamura S, Yao T, Hayashi K, Iida M.

Dis Colon Rectum. 2007 Feb;50(2):223-31.

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