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Items: 18

1.

Investigation of H2AX methylation by the SUV39H2 protein lysine methyltransferase.

Schuhmacher MK, Kudithipudi S, Jeltsch A.

FEBS Lett. 2016 May 14. doi: 10.1002/1873-3468.12216. [Epub ahead of print]

PMID:
27177470
2.

Specificity of the SUV4-20H1 and SUV4-20H2 protein lysine methyltransferases and methylation of novel substrates.

Weirich S, Kudithipudi S, Jeltsch A.

J Mol Biol. 2016 Jun 5;428(11):2344-58. doi: 10.1016/j.jmb.2016.04.015. Epub 2016 Apr 20.

PMID:
27105552
3.

Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates.

Kusevic D, Kudithipudi S, Jeltsch A.

J Biol Chem. 2016 Mar 18;291(12):6124-33. doi: 10.1074/jbc.M115.711952. Epub 2016 Jan 21.

PMID:
26797129
4.

Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase.

Weirich S, Kusevic D, Kudithipudi S, Jeltsch A.

Sci Rep. 2015 Sep 22;5:13813. doi: 10.1038/srep13813.

5.

Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.

Weirich S, Kudithipudi S, Kycia I, Jeltsch A.

Clin Epigenetics. 2015 Mar 28;7(1):36. doi: 10.1186/s13148-015-0075-3. eCollection 2015.

6.

Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays.

Kudithipudi S, Kusevic D, Weirich S, Jeltsch A.

J Vis Exp. 2014 Nov 29;(93):e52203. doi: 10.3791/52203.

PMID:
25489813
7.

Activity and specificity of the human SUV39H2 protein lysine methyltransferase.

Schuhmacher MK, Kudithipudi S, Kusevic D, Weirich S, Jeltsch A.

Biochim Biophys Acta. 2015 Jan;1849(1):55-63. doi: 10.1016/j.bbagrm.2014.11.005. Epub 2014 Nov 22.

PMID:
25459750
8.

Application of histone modification-specific interaction domains as an alternative to antibodies.

Kungulovski G, Kycia I, Tamas R, Jurkowska RZ, Kudithipudi S, Henry C, Reinhardt R, Labhart P, Jeltsch A.

Genome Res. 2014 Nov;24(11):1842-53. doi: 10.1101/gr.170985.113. Epub 2014 Oct 9.

9.

Role of somatic cancer mutations in human protein lysine methyltransferases.

Kudithipudi S, Jeltsch A.

Biochim Biophys Acta. 2014 Dec;1846(2):366-79. doi: 10.1016/j.bbcan.2014.08.002. Epub 2014 Aug 12. Review.

PMID:
25123655
10.

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

Kudithipudi S, Lungu C, Rathert P, Happel N, Jeltsch A.

Chem Biol. 2014 Feb 20;21(2):226-37. doi: 10.1016/j.chembiol.2013.10.016. Epub 2014 Jan 9.

11.

The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

Kycia I, Kudithipudi S, Tamas R, Kungulovski G, Dhayalan A, Jeltsch A.

J Mol Biol. 2014 Apr 17;426(8):1651-60. doi: 10.1016/j.jmb.2013.08.009. Epub 2013 Aug 15.

PMID:
23954330
12.

Non-radioactive protein lysine methyltransferase microplate assay based on reading domains.

Kudithipudi S, Kusevic D, Jeltsch A.

ChemMedChem. 2014 Mar;9(3):554-9. doi: 10.1002/cmdc.201300111. Epub 2013 May 13.

PMID:
23671032
13.

The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues.

Kudithipudi S, Dhayalan A, Kebede AF, Jeltsch A.

Biochimie. 2012 Nov;94(11):2212-8. doi: 10.1016/j.biochi.2012.04.024. Epub 2012 May 11.

PMID:
22583696
14.

A fluorescence-based supramolecular tandem assay for monitoring lysine methyltransferase activity in homogeneous solution.

Florea M, Kudithipudi S, Rei A, González-Álvarez MJ, Jeltsch A, Nau WM.

Chemistry. 2012 Mar 19;18(12):3521-8. doi: 10.1002/chem.201103397. Epub 2012 Feb 24.

PMID:
22367964
15.

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails.

Bock I, Kudithipudi S, Tamas R, Kungulovski G, Dhayalan A, Jeltsch A.

BMC Biochem. 2011 Aug 31;12:48. doi: 10.1186/1471-2091-12-48.

16.

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9.

Dhayalan A, Tamas R, Bock I, Tattermusch A, Dimitrova E, Kudithipudi S, Ragozin S, Jeltsch A.

Hum Mol Genet. 2011 Jun 1;20(11):2195-203. doi: 10.1093/hmg/ddr107. Epub 2011 Mar 18.

17.

Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase.

Dhayalan A, Kudithipudi S, Rathert P, Jeltsch A.

Chem Biol. 2011 Jan 28;18(1):111-20. doi: 10.1016/j.chembiol.2010.11.014.

18.

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays.

Bock I, Dhayalan A, Kudithipudi S, Brandt O, Rathert P, Jeltsch A.

Epigenetics. 2011 Feb;6(2):256-63. Epub 2011 Feb 1.

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