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Items: 1 to 20 of 107

1.

Modeling simple repeat expansion diseases with iPSC technology.

Jaworska E, Kozlowska E, Switonski PM, Krzyzosiak WJ.

Cell Mol Life Sci. 2016 Jun 3. [Epub ahead of print] Review.

PMID:
27261369
2.

Nuclear speckles are detention centers for transcripts containing expanded CAG repeats.

Urbanek MO, Jazurek M, Switonski PM, Figura G, Krzyzosiak WJ.

Biochim Biophys Acta. 2016 May 27;1862(9):1513-1520. doi: 10.1016/j.bbadis.2016.05.015. [Epub ahead of print]

PMID:
27239700
3.

siRNA release from pri-miRNA scaffolds is controlled by the sequence and structure of RNA.

Galka-Marciniak P, Olejniczak M, Starega-Roslan J, Szczesniak MW, Makalowska I, Krzyzosiak WJ.

Biochim Biophys Acta. 2016 Apr;1859(4):639-49. doi: 10.1016/j.bbagrm.2016.02.014. Epub 2016 Feb 26.

PMID:
26921501
4.

RNA FISH for detecting expanded repeats in human diseases.

Urbanek MO, Krzyzosiak WJ.

Methods. 2016 Apr 1;98:115-23. doi: 10.1016/j.ymeth.2015.11.017. Epub 2015 Nov 23.

PMID:
26615955
5.

Sequence-non-specific effects generated by various types of RNA interference triggers.

Olejniczak M, Urbanek MO, Jaworska E, Witucki L, Szczesniak MW, Makalowska I, Krzyzosiak WJ.

Biochim Biophys Acta. 2016 Feb;1859(2):306-14. doi: 10.1016/j.bbagrm.2015.11.005. Epub 2015 Nov 22.

PMID:
26612823
6.

Nucleotide sequence of miRNA precursor contributes to cleavage site selection by Dicer.

Starega-Roslan J, Galka-Marciniak P, Krzyzosiak WJ.

Nucleic Acids Res. 2015 Dec 15;43(22):10939-51. doi: 10.1093/nar/gkv968. Epub 2015 Sep 30.

7.

Cooperation meets competition in microRNA-mediated DMPK transcript regulation.

Koscianska E, Witkos TM, Kozlowska E, Wojciechowska M, Krzyzosiak WJ.

Nucleic Acids Res. 2015 Oct 30;43(19):9500-18. doi: 10.1093/nar/gkv849. Epub 2015 Aug 24.

8.

In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats.

Figura G, Koscianska E, Krzyzosiak WJ.

Int J Mol Sci. 2015 Aug 11;16(8):18741-51. doi: 10.3390/ijms160818741.

9.

Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway.

Szlachcic WJ, Switonski PM, Krzyzosiak WJ, Figlerowicz M, Figiel M.

Dis Model Mech. 2015 Sep;8(9):1047-57. doi: 10.1242/dmm.019406. Epub 2015 Jun 18.

10.

Small RNA Detection by in Situ Hybridization Methods.

Urbanek MO, Nawrocka AU, Krzyzosiak WJ.

Int J Mol Sci. 2015 Jun 10;16(6):13259-86. doi: 10.3390/ijms160613259. Review.

11.

Characterization of a naturally occurring truncated Dicer.

Mosca N, Starega-Roslan J, Castiello F, Russo A, Krzyzosiak WJ, Potenza N.

Mol Biol Rep. 2015 Aug;42(8):1333-40. doi: 10.1007/s11033-015-3878-6. Epub 2015 Apr 25.

PMID:
25911188
12.

The role of the immune system in triplet repeat expansion diseases.

Olejniczak M, Urbanek MO, Krzyzosiak WJ.

Mediators Inflamm. 2015;2015:873860. doi: 10.1155/2015/873860. Epub 2015 Mar 22. Review.

13.

Sequence features of Drosha and Dicer cleavage sites affect the complexity of isomiRs.

Starega-Roslan J, Witkos TM, Galka-Marciniak P, Krzyzosiak WJ.

Int J Mol Sci. 2015 Apr 10;16(4):8110-27. doi: 10.3390/ijms16048110.

14.

RNA imaging in living cells - methods and applications.

Urbanek MO, Galka-Marciniak P, Olejniczak M, Krzyzosiak WJ.

RNA Biol. 2014;11(8):1083-95. doi: 10.4161/rna.35506. Review.

15.

A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.

Switonski PM, Szlachcic WJ, Krzyzosiak WJ, Figiel M.

Neurobiol Dis. 2015 Jan;73:174-88. doi: 10.1016/j.nbd.2014.09.020. Epub 2014 Oct 7.

16.

RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders.

Wojciechowska M, Olejniczak M, Galka-Marciniak P, Jazurek M, Krzyzosiak WJ.

Nucleic Acids Res. 2014 Oct 29;42(19):11849-64. doi: 10.1093/nar/gku794. Epub 2014 Sep 12. Review.

17.

Oligonucleotide-based strategies to combat polyglutamine diseases.

Fiszer A, Krzyzosiak WJ.

Nucleic Acids Res. 2014 Jun;42(11):6787-810. doi: 10.1093/nar/gku385. Epub 2014 May 21. Review.

18.

Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.

Wojciechowska M, Taylor K, Sobczak K, Napierala M, Krzyzosiak WJ.

RNA Biol. 2014;11(6):742-54. Epub 2014 Apr 24.

19.

The panorama of miRNA-mediated mechanisms in mammalian cells.

Stroynowska-Czerwinska A, Fiszer A, Krzyzosiak WJ.

Cell Mol Life Sci. 2014 Jun;71(12):2253-70. doi: 10.1007/s00018-013-1551-6. Epub 2014 Jan 29. Review.

20.

Current understanding of the role of microRNAs in spinocerebellar ataxias.

Koscianska E, Krzyzosiak WJ.

Cerebellum Ataxias. 2014 Aug 7;1:7. doi: 10.1186/2053-8871-1-7. eCollection 2014. Review.

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