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Results: 1 to 20 of 92

1.

A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.

Switonski PM, Szlachcic WJ, Krzyzosiak WJ, Figiel M.

Neurobiol Dis. 2014 Oct 7. pii: S0969-9961(14)00293-9. doi: 10.1016/j.nbd.2014.09.020. [Epub ahead of print]

PMID:
25301414
[PubMed - as supplied by publisher]
2.

RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders.

Wojciechowska M, Olejniczak M, Galka-Marciniak P, Jazurek M, Krzyzosiak WJ.

Nucleic Acids Res. 2014 Sep 12. pii: gku794. [Epub ahead of print]

PMID:
25217582
[PubMed - as supplied by publisher]
Free Article
3.

Oligonucleotide-based strategies to combat polyglutamine diseases.

Fiszer A, Krzyzosiak WJ.

Nucleic Acids Res. 2014;42(11):6787-810. doi: 10.1093/nar/gku385. Epub 2014 May 21. Review.

PMID:
24848018
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.

Wojciechowska M, Taylor K, Sobczak K, Napierala M, Krzyzosiak WJ.

RNA Biol. 2014 Jun;11(6):742-54. Epub 2014 Apr 24.

PMID:
24824895
[PubMed - in process]
Free Article
5.

The panorama of miRNA-mediated mechanisms in mammalian cells.

Stroynowska-Czerwinska A, Fiszer A, Krzyzosiak WJ.

Cell Mol Life Sci. 2014 Jun;71(12):2253-70. doi: 10.1007/s00018-013-1551-6. Epub 2014 Jan 29. Review.

PMID:
24468964
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression.

Fiszer A, Olejniczak M, Galka-Marciniak P, Mykowska A, Krzyzosiak WJ.

Nucleic Acids Res. 2013 Dec;41(22):10426-37. doi: 10.1093/nar/gkt825. Epub 2013 Sep 13.

PMID:
24038471
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs.

Kozlowska E, Krzyzosiak WJ, Koscianska E.

Int J Mol Sci. 2013 Aug 19;14(8):16999-7016. doi: 10.3390/ijms140816999.

PMID:
23965969
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Coiled-coil motifs enhance the toxicity of polyQ proteins (comment on DOI 10.1002/bies.201300001).

Krzyzosiak WJ.

Bioessays. 2013 Jun;35(6):500. doi: 10.1002/bies.201300056. No abstract available.

PMID:
23674356
[PubMed - indexed for MEDLINE]
9.

RNA toxicity in polyglutamine disorders: concepts, models, and progress of research.

Fiszer A, Krzyzosiak WJ.

J Mol Med (Berl). 2013 Jun;91(6):683-91. doi: 10.1007/s00109-013-1016-2. Epub 2013 Mar 20. Review.

PMID:
23512265
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Triplet repeats in transcripts: structural insights into RNA toxicity.

Galka-Marciniak P, Urbanek MO, Krzyzosiak WJ.

Biol Chem. 2012 Nov;393(11):1299-315. doi: 10.1515/hsz-2012-0218. Review.

PMID:
23052488
[PubMed - indexed for MEDLINE]
11.

Analysis of microRNA length variety generated by recombinant human Dicer.

Starega-Roslan J, Krzyzosiak WJ.

Methods Mol Biol. 2013;936:21-34.

PMID:
23007496
[PubMed - indexed for MEDLINE]
12.

Mouse models of polyglutamine diseases: review and data table. Part I.

Figiel M, Szlachcic WJ, Switonski PM, Gabka A, Krzyzosiak WJ.

Mol Neurobiol. 2012 Oct;46(2):393-429. doi: 10.1007/s12035-012-8315-4. Epub 2012 Sep 7. Review.

PMID:
22956270
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.

Switonski PM, Szlachcic WJ, Gabka A, Krzyzosiak WJ, Figiel M.

Mol Neurobiol. 2012 Oct;46(2):430-66. doi: 10.1007/s12035-012-8316-3. Epub 2012 Sep 4. Review.

PMID:
22944909
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crystallographic characterization of CCG repeats.

Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W.

Nucleic Acids Res. 2012 Sep;40(16):8155-62. doi: 10.1093/nar/gks557. Epub 2012 Jun 19.

PMID:
22718980
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

RNAimmuno: a database of the nonspecific immunological effects of RNA interference and microRNA reagents.

Olejniczak M, Galka-Marciniak P, Polak K, Fligier A, Krzyzosiak WJ.

RNA. 2012 May;18(5):930-5. doi: 10.1261/rna.025627.110. Epub 2012 Mar 12.

PMID:
22411954
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases.

Fiszer A, Olejniczak M, Switonski PM, Wroblewska JP, Wisniewska-Kruk J, Mykowska A, Krzyzosiak WJ.

BMC Mol Biol. 2012 Mar 7;13:6. doi: 10.1186/1471-2199-13-6.

PMID:
22397573
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Diced triplets expose neurons to RISC.

Rudnicki DD, Margolis RL, Pearson CE, Krzyzosiak WJ.

PLoS Genet. 2012;8(2):e1002545. doi: 10.1371/journal.pgen.1002545. Epub 2012 Feb 23. No abstract available.

PMID:
22383898
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The role of Dicer protein partners in the processing of microRNA precursors.

Koscianska E, Starega-Roslan J, Krzyzosiak WJ.

PLoS One. 2011;6(12):e28548. doi: 10.1371/journal.pone.0028548. Epub 2011 Dec 6.

PMID:
22163034
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Recent advances in understanding of the immunological off-target effects of siRNA.

Olejniczak M, Polak K, Galka-Marciniak P, Krzyzosiak WJ.

Curr Gene Ther. 2011 Dec;11(6):532-43. Review.

PMID:
22023470
[PubMed - indexed for MEDLINE]
20.

Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target.

Krzyzosiak WJ, Sobczak K, Wojciechowska M, Fiszer A, Mykowska A, Kozlowski P.

Nucleic Acids Res. 2012 Jan;40(1):11-26. doi: 10.1093/nar/gkr729. Epub 2011 Sep 9. Review.

PMID:
21908410
[PubMed - indexed for MEDLINE]
Free PMC Article

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