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Results: 1 to 20 of 149

1.

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.

Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P.

Elife. 2015 Apr 15;4. doi: 10.7554/eLife.07314. [Epub ahead of print]

2.

NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer.

Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, Krogan NJ, Bivona TG.

Cell Rep. 2015 Apr 7;11(1):98-110. doi: 10.1016/j.celrep.2015.03.012. Epub 2015 Apr 2.

3.

Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast.

Patrick KL, Ryan CJ, Xu J, Lipp JJ, Nissen KE, Roguev A, Shales M, Krogan NJ, Guthrie C.

PLoS Genet. 2015 Mar 31;11(3):e1005074. doi: 10.1371/journal.pgen.1005074. eCollection 2015 Feb.

4.

Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants.

Sánchez A, Roguev A, Krogan NJ, Russell P.

G3 (Bethesda). 2015 Mar 19. pii: g3.115.017251. doi: 10.1534/g3.115.017251. [Epub ahead of print]

5.

Scoring Large-Scale Affinity Purification Mass Spectrometry Datasets with MiST.

Verschueren E, Von Dollen J, Cimermancic P, Gulbahce N, Sali A, Krogan NJ.

Curr Protoc Bioinformatics. 2015 Mar 9;49:8.19.1-8.19.16. doi: 10.1002/0471250953.bi0819s49.

PMID:
25754993
6.

A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay.

Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M.

Mol Cell. 2015 Jan 22;57(2):329-40. doi: 10.1016/j.molcel.2014.12.028.

PMID:
25616068
7.

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

Davis ZH, Verschueren E, Jang GM, Kleffman K, Johnson JR, Park J, Von Dollen J, Maher MC, Johnson T, Newton W, Jäger S, Shales M, Horner J, Hernandez RD, Krogan NJ, Glaunsinger BA.

Mol Cell. 2015 Jan 22;57(2):349-60. doi: 10.1016/j.molcel.2014.11.026. Epub 2014 Dec 24.

PMID:
25544563
8.

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S.

Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12.

PMID:
25501949
9.

Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.

Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT.

Genes Dev. 2014 Nov 15;28(22):2547-63. doi: 10.1101/gad.249425.114.

PMID:
25403183
10.

Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts.

Eifler TT, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson JR, Luo Z, Krogan NJ, Peterlin BM.

Mol Cell Biol. 2015 Jan;35(2):468-78. doi: 10.1128/MCB.01157-14. Epub 2014 Nov 10.

PMID:
25384976
11.

Cullin E3 ligases and their rewiring by viral factors.

Mahon C, Krogan NJ, Craik CS, Pick E.

Biomolecules. 2014 Oct 13;4(4):897-930. doi: 10.3390/biom4040897. Review.

12.

Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.

Tosti E, Katakowski JA, Schaetzlein S, Kim HS, Ryan CJ, Shales M, Roguev A, Krogan NJ, Palliser D, Keogh MC, Edelmann W.

Genome Med. 2014 Sep 17;6(9):68. doi: 10.1186/s13073-014-0068-4. eCollection 2014.

13.

Quantitative analysis of triple-mutant genetic interactions.

Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ.

Nat Protoc. 2014 Aug;9(8):1867-81. doi: 10.1038/nprot.2014.127. Epub 2014 Jul 10.

14.

Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Anver S, Roguev A, Zofall M, Krogan NJ, Grewal SI, Harmer SL.

EMBO Rep. 2014 Aug;15(8):894-902. doi: 10.15252/embr.201438902. Epub 2014 Jun 23.

PMID:
24957674
15.
16.

Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate.

Moehle EA, Braberg H, Krogan NJ, Guthrie C.

RNA Biol. 2014;11(4):313-9. doi: 10.4161/rna.28646. Epub 2014 Apr 2. Review.

17.

Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae.

Leung GP, Aristizabal MJ, Krogan NJ, Kobor MS.

G3 (Bethesda). 2014 Apr 2;4(6):1059-69. doi: 10.1534/g3.114.011205.

18.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

19.

Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.

Martín GM, King DA, Green EM, Garcia-Nieto PE, Alexander R, Collins SR, Krogan NJ, Gozani OP, Morrison AJ.

Epigenetics. 2014 Apr;9(4):513-22. doi: 10.4161/epi.27645. Epub 2014 Jan 17.

20.

A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation.

Kabeche R, Roguev A, Krogan NJ, Moseley JB.

J Cell Sci. 2014 Mar 15;127(Pt 6):1318-26. doi: 10.1242/jcs.143545. Epub 2014 Jan 16.

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