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Results: 1 to 20 of 137

1.

Quantitative analysis of triple-mutant genetic interactions.

Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ.

Nat Protoc. 2014 Aug;9(8):1867-81. doi: 10.1038/nprot.2014.127. Epub 2014 Jul 10.

PMID:
25010907
[PubMed - in process]
2.

Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Anver S, Roguev A, Zofall M, Krogan NJ, Grewal SI, Harmer SL.

EMBO Rep. 2014 Jun 23. pii: e201438902. [Epub ahead of print]

PMID:
24957674
[PubMed - as supplied by publisher]
Free Article
3.

Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations.

Braberg H, Moehle EA, Shales M, Guthrie C, Krogan NJ.

Bioessays. 2014 Jul;36(7):706-13. doi: 10.1002/bies.201400044. Epub 2014 May 20.

PMID:
24842270
[PubMed - in process]
4.

Adventures in time and space: splicing efficiency and RNA polymerase II elongation rate.

Moehle EA, Braberg H, Krogan NJ, Guthrie C.

RNA Biol. 2014 Apr;11(4):313-9. doi: 10.4161/rna.28646. Epub 2014 Apr 2.

PMID:
24717535
[PubMed - in process]
5.

Conditional Genetic Interactions of RTT107, SLX4, and HRQ1 Reveal Dynamic Networks upon DNA Damage in S. cerevisiae.

Leung GP, Aristizabal MJ, Krogan NJ, Kobor MS.

G3 (Bethesda). 2014 Apr 2;4(6):1059-69. doi: 10.1534/g3.114.011205.

PMID:
24700328
[PubMed - in process]
Free PMC Article
6.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

PMID:
24565511
[PubMed - in process]
Free PMC Article
7.

Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.

Martín GM, King DA, Green EM, Garcia-Nieto PE, Alexander R, Collins SR, Krogan NJ, Gozani OP, Morrison AJ.

Epigenetics. 2014 Apr 1;9(4):513-22. doi: 10.4161/epi.27645. Epub 2014 Jan 17.

PMID:
24442241
[PubMed - in process]
8.

A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation.

Kabeche R, Roguev A, Krogan NJ, Moseley JB.

J Cell Sci. 2014 Mar 15;127(Pt 6):1318-26. doi: 10.1242/jcs.143545. Epub 2014 Jan 16.

PMID:
24434583
[PubMed - in process]
9.

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.

Lu H, Li Z, Xue Y, Schulze-Gahmen U, Johnson JR, Krogan NJ, Alber T, Zhou Q.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E15-24. doi: 10.1073/pnas.1318503111. Epub 2013 Dec 23.

PMID:
24367103
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Evolution and functional cross-talk of protein post-translational modifications.

Beltrao P, Bork P, Krogan NJ, van Noort V.

Mol Syst Biol. 2013 Dec 22;9:714. doi: 10.1002/msb.201304521. Print 2013. Review.

PMID:
24366814
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.

Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM.

Cell Rep. 2013 Dec 26;5(6):1725-36. doi: 10.1016/j.celrep.2013.11.040. Epub 2013 Dec 19.

PMID:
24360963
[PubMed - in process]
Free PMC Article
12.

IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.

Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC.

Science. 2014 Jan 24;343(6169):428-32. doi: 10.1126/science.1243640. Epub 2013 Dec 19.

PMID:
24356113
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

High-resolution network biology: connecting sequence with function.

Ryan CJ, Cimermančič P, Szpiech ZA, Sali A, Hernandez RD, Krogan NJ.

Nat Rev Genet. 2013 Dec;14(12):865-79. doi: 10.1038/nrg3574. Epub 2013 Nov 7. Review.

PMID:
24197012
[PubMed - indexed for MEDLINE]
14.

High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8.

Aristizabal MJ, Negri GL, Benschop JJ, Holstege FC, Krogan NJ, Kobor MS.

PLoS Genet. 2013 Aug;9(8):e1003758. doi: 10.1371/journal.pgen.1003758. Epub 2013 Aug 29.

PMID:
24009531
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, Kaplan CD, Krogan NJ.

Cell. 2013 Aug 15;154(4):775-88. doi: 10.1016/j.cell.2013.07.033. Epub 2013 Aug 8.

PMID:
23932120
[PubMed - indexed for MEDLINE]
16.

A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.

Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R Jr, Simons K, Krogan NJ, Ernst R.

Mol Cell. 2013 Aug 22;51(4):519-30. doi: 10.1016/j.molcel.2013.06.014. Epub 2013 Jul 25.

PMID:
23891562
[PubMed - indexed for MEDLINE]
17.

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.

Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.

Nat Methods. 2013 Jul;10(7):676-82. doi: 10.1038/nmeth.2519. Epub 2013 Jun 9.

PMID:
23749301
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.

Haber JE, Braberg H, Wu Q, Alexander R, Haase J, Ryan C, Lipkin-Moore Z, Franks-Skiba KE, Johnson T, Shales M, Lenstra TL, Holstege FC, Johnson JR, Bloom K, Krogan NJ.

Cell Rep. 2013 Jun 27;3(6):2168-78. doi: 10.1016/j.celrep.2013.05.007. Epub 2013 Jun 6.

PMID:
23746449
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

All or nothing: protein complexes flip essentiality between distantly related eukaryotes.

Ryan CJ, Krogan NJ, Cunningham P, Cagney G.

Genome Biol Evol. 2013;5(6):1049-59. doi: 10.1093/gbe/evt074.

PMID:
23661563
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.

Schulze-Gahmen U, Upton H, Birnberg A, Bao K, Chou S, Krogan NJ, Zhou Q, Alber T.

Elife (Cambridge). 2013 Mar 5;2:e00327. doi: 10.7554/eLife.00327.

PMID:
23471103
[PubMed]
Free PMC Article

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