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Items: 1 to 20 of 161

1.

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.

Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs DH, Hamilton J, Leon PE, Chawdury A, Tripathi S, Melegari C, Campisi L, Hai R, Metreveli G, Gamarnik AV, García-Sastre A, Greenbaum B, Simon V, Fernandez-Sesma A, Krogan NJ, Mulder LC, van Bakel H, Tortorella D, Taunton J, Palese P, Marazzi I.

Immunity. 2016 Jan 19;44(1):46-58. doi: 10.1016/j.immuni.2015.12.017.

PMID:
26789921
2.

CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.

Pak V, Eifler TT, Jäger S, Krogan NJ, Fujinaga K, Peterlin BM.

Cell Host Microbe. 2015 Nov 11;18(5):560-70. doi: 10.1016/j.chom.2015.10.012.

PMID:
26567509
3.

Discovery and functional characterization of a neomorphic PTEN mutation.

Costa HA, Leitner MG, Sos ML, Mavrantoni A, Rychkova A, Johnson JR, Newton BW, Yee MC, De La Vega FM, Ford JM, Krogan NJ, Shokat KM, Oliver D, Halaszovich CR, Bustamante CD.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13976-81. doi: 10.1073/pnas.1422504112. Epub 2015 Oct 26.

4.

Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.

Johnson JR, Santos SD, Johnson T, Pieper U, Strumillo M, Wagih O, Sali A, Krogan NJ, Beltrao P.

PLoS Comput Biol. 2015 Aug 27;11(8):e1004362. doi: 10.1371/journal.pcbi.1004362. eCollection 2015 Aug.

5.

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF.

Elife. 2015 Aug 22;4. doi: 10.7554/eLife.07519.

6.

Comparative mapping of host-pathogen protein-protein interactions.

Shah PS, Wojcechowskyj JA, Eckhardt M, Krogan NJ.

Curr Opin Microbiol. 2015 Oct;27:62-8. doi: 10.1016/j.mib.2015.07.008. Epub 2015 Aug 10. Review.

PMID:
26275922
7.

Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1.

Mark KG, Meza-Gutierrez F, Johnson JR, Newton BW, Krogan NJ, Toczyski DP.

Biochemistry. 2015 Jul 28;54(29):4423-6. doi: 10.1021/acs.biochem.5b00504. Epub 2015 Jul 17.

PMID:
26161950
8.

Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.

Mirrashidi KM, Elwell CA, Verschueren E, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, Jäger S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, Penn B, Shales M, Cox JS, Starnbach MN, Derre I, Valdivia R, Krogan NJ, Engel J.

Cell Host Microbe. 2015 Jul 8;18(1):109-21. doi: 10.1016/j.chom.2015.06.004. Epub 2015 Jun 25.

PMID:
26118995
9.

The cancer cell map initiative: defining the hallmark networks of cancer.

Krogan NJ, Lippman S, Agard DA, Ashworth A, Ideker T.

Mol Cell. 2015 May 21;58(4):690-8. doi: 10.1016/j.molcel.2015.05.008. Review.

PMID:
26000852
10.

Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.

Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ.

Cell Rep. 2015 May 26;11(8):1236-50. doi: 10.1016/j.celrep.2015.04.038. Epub 2015 May 14.

11.

Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining.

Jessulat M, Malty RH, Nguyen-Tran DH, Deineko V, Aoki H, Vlasblom J, Omidi K, Jin K, Minic Z, Hooshyar M, Burnside D, Samanfar B, Phanse S, Freywald T, Prasad B, Zhang Z, Vizeacoumar F, Krogan NJ, Freywald A, Golshani A, Babu M.

Mol Cell Biol. 2015 Jul;35(14):2448-63. doi: 10.1128/MCB.00007-15. Epub 2015 May 11.

12.

Differential genetic interactions of yeast stress response MAPK pathways.

Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ.

Mol Syst Biol. 2015 Apr 17;11(4):800. doi: 10.15252/msb.20145606.

13.

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.

Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P.

Elife. 2015 Apr 15;4:e07314. doi: 10.7554/eLife.07314.

14.

NF-κB-activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer.

Blakely CM, Pazarentzos E, Olivas V, Asthana S, Yan JJ, Tan I, Hrustanovic G, Chan E, Lin L, Neel DS, Newton W, Bobb KL, Fouts TR, Meshulam J, Gubens MA, Jablons DM, Johnson JR, Bandyopadhyay S, Krogan NJ, Bivona TG.

Cell Rep. 2015 Apr 7;11(1):98-110. doi: 10.1016/j.celrep.2015.03.012. Epub 2015 Apr 2.

15.

Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast.

Patrick KL, Ryan CJ, Xu J, Lipp JJ, Nissen KE, Roguev A, Shales M, Krogan NJ, Guthrie C.

PLoS Genet. 2015 Mar 31;11(3):e1005074. doi: 10.1371/journal.pgen.1005074. eCollection 2015 Mar.

16.

Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants.

Sánchez A, Roguev A, Krogan NJ, Russell P.

G3 (Bethesda). 2015 Mar 19;5(5):953-62. doi: 10.1534/g3.115.017251.

17.

Scoring Large-Scale Affinity Purification Mass Spectrometry Datasets with MiST.

Verschueren E, Von Dollen J, Cimermancic P, Gulbahce N, Sali A, Krogan NJ.

Curr Protoc Bioinformatics. 2015 Mar 9;49:8.19.1-8.19.16. doi: 10.1002/0471250953.bi0819s49.

PMID:
25754993
18.

A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay.

Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M.

Mol Cell. 2015 Jan 22;57(2):329-40. doi: 10.1016/j.molcel.2014.12.028.

19.

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

Davis ZH, Verschueren E, Jang GM, Kleffman K, Johnson JR, Park J, Von Dollen J, Maher MC, Johnson T, Newton W, Jäger S, Shales M, Horner J, Hernandez RD, Krogan NJ, Glaunsinger BA.

Mol Cell. 2015 Jan 22;57(2):349-60. doi: 10.1016/j.molcel.2014.11.026. Epub 2014 Dec 24.

20.

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S.

Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12.

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