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Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.
Friess MC, Kritikos I, Schineis P, Medina-Sanchez JD, Gkountidi AO, Vallone A, Sigmund EC, Schwitter C, Vranova M, Matti C, Arasa J, Saygili Demir C, Bovay E, Proulx ST, Tomura M, Rot A, Legler DF, Petrova TV, Halin C. Friess MC, et al. Among authors: kritikos i. Cell Rep. 2022 Feb 1;38(5):110334. doi: 10.1016/j.celrep.2022.110334. Cell Rep. 2022. PMID: 35108538 Free article.
Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation.
Arasa J, Collado-Diaz V, Kritikos I, Medina-Sanchez JD, Friess MC, Sigmund EC, Schineis P, Hunter MC, Tacconi C, Paterson N, Nagasawa T, Kiefer F, Makinen T, Detmar M, Moser M, Lämmermann T, Halin C. Arasa J, et al. Among authors: kritikos i. J Exp Med. 2021 Jul 5;218(7):e20201413. doi: 10.1084/jem.20201413. Epub 2021 May 14. J Exp Med. 2021. PMID: 33988714 Free PMC article.
Evaluation of potential retinal toxicity of adalimumab (Humira).
Tsilimbaris M, Diakonis VF, Naoumidi I, Charisis S, Kritikos I, Chatzithanasis G, Papadaki T, Plainis S. Tsilimbaris M, et al. Among authors: kritikos i. Graefes Arch Clin Exp Ophthalmol. 2009 Aug;247(8):1119-25. doi: 10.1007/s00417-009-1065-y. Epub 2009 Mar 19. Graefes Arch Clin Exp Ophthalmol. 2009. PMID: 19296122
The programmed death 1/programmed death ligand 1 inhibitory pathway is up-regulated in rheumatoid synovium and regulates peripheral T cell responses in human and murine arthritis.
Raptopoulou AP, Bertsias G, Makrygiannakis D, Verginis P, Kritikos I, Tzardi M, Klareskog L, Catrina AI, Sidiropoulos P, Boumpas DT. Raptopoulou AP, et al. Among authors: kritikos i. Arthritis Rheum. 2010 Jul;62(7):1870-80. doi: 10.1002/art.27500. Arthritis Rheum. 2010. PMID: 20506224 Free article.
Gene expression in systemic lupus erythematosus: bone marrow analysis differentiates active from inactive disease and reveals apoptosis and granulopoiesis signatures.
Nakou M, Knowlton N, Frank MB, Bertsias G, Osban J, Sandel CE, Papadaki H, Raptopoulou A, Sidiropoulos P, Kritikos I, Tassiulas I, Centola M, Boumpas DT. Nakou M, et al. Among authors: kritikos i. Arthritis Rheum. 2008 Nov;58(11):3541-9. doi: 10.1002/art.23961. Arthritis Rheum. 2008. PMID: 18975309 Free PMC article.