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Expression of IL-20 in synovium and lesional skin of patients with psoriatic arthritis: differential response to alefacept treatment.

Lebre MC, Jonckheere CL, Kraan MC, van Kuijk AW, Bos JD, de Rie M, Gerlag DM, Tak PP.

Arthritis Res Ther. 2012 Sep 24;14(5):R200. doi: 10.1186/ar4038.


CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial.

van Kuijk AW, Vergunst CE, Gerlag DM, Bresnihan B, Gomez-Reino JJ, Rouzier R, Verschueren PC, van der Leij C, Maas M, Kraan MC, Tak PP.

Ann Rheum Dis. 2010 Nov;69(11):2013-6. doi: 10.1136/ard.2010.131235. Epub 2010 Aug 6. Erratum in: Ann Rheum Dis. 2013 Apr;72(4):630. van de Leij, Christiaan [corrected to van der Leij, Christiaan].


Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide.

van der Heijden JW, Oerlemans R, Tak PP, Assaraf YG, Kraan MC, Scheffer GL, van der Laken CJ, Lems WF, Scheper RJ, Dijkmans BA, Jansen G.

Arthritis Rheum. 2009 Mar;60(3):669-77. doi: 10.1002/art.24354.


Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients.

van der Heijden JW, Oerlemans R, Dijkmans BA, Qi H, van der Laken CJ, Lems WF, Jackman AL, Kraan MC, Tak PP, Ratnam M, Jansen G.

Arthritis Rheum. 2009 Jan;60(1):12-21. doi: 10.1002/art.24219.


Clinical identification and treatment of a rapidly progressing disease state in patients with rheumatoid arthritis.

Emery P, McInnes IB, van Vollenhoven R, Kraan MC.

Rheumatology (Oxford). 2008 Apr;47(4):392-8. Epub 2007 Dec 18. Review.


The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor alpha expression in the synovium.

Wijbrandts CA, Dijkgraaf MG, Kraan MC, Vinkenoog M, Smeets TJ, Dinant H, Vos K, Lems WF, Wolbink GJ, Sijpkens D, Dijkmans BA, Tak PP.

Ann Rheum Dis. 2008 Aug;67(8):1139-44. Epub 2007 Nov 29.


Quantitative image analysis of synovial tissue.

van der Hall PO, Kraan MC, Tak PP.

Methods Mol Med. 2007;135:121-43.


Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with alpha2 macroglobulin in serum of rheumatoid arthritis patients.

Tchetverikov I, Kraan MC, van El B, Hanemaaijer R, DeGroot J, Huizinga TW.

Ann Rheum Dis. 2008 Jan;67(1):128-30. Epub 2007 Sep 17.


Pretreatment macrophage infiltration of the synovium predicts the clinical effect of both radiation synovectomy and intra-articular glucocorticoids.

Jahangier ZN, Jacobs JW, Kraan MC, Wenting MJ, Smeets TJ, Bijlsma JW, Lafeber FP, Tak PP.

Ann Rheum Dis. 2006 Oct;65(10):1286-92. Epub 2006 Apr 20.


Digital image analysis for the evaluation of the inflammatory infiltrate in psoriasis.

Goedkoop AY, de Rie MA, Teunissen MB, Picavet DI, van der Hall PO, Bos JD, Tak PP, Kraan MC.

Arch Dermatol Res. 2005 Aug;297(2):51-9. Epub 2005 Oct 8.


Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes.

Berckmans RJ, Nieuwland R, Kraan MC, Schaap MC, Pots D, Smeets TJ, Sturk A, Tak PP.

Arthritis Res Ther. 2005;7(3):R536-44. Epub 2005 Mar 1.


Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue.

Kop EN, Kwakkenbos MJ, Teske GJ, Kraan MC, Smeets TJ, Stacey M, Lin HH, Tak PP, Hamann J.

Arthritis Rheum. 2005 Feb;52(2):442-50.


Effects of oral prednisolone on biomarkers in synovial tissue and clinical improvement in rheumatoid arthritis.

Gerlag DM, Haringman JJ, Smeets TJ, Zwinderman AH, Kraan MC, Laud PJ, Morgan S, Nash AF, Tak PP.

Arthritis Rheum. 2004 Dec;50(12):3783-91.


Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis.

Haringman JJ, Gerlag DM, Zwinderman AH, Smeets TJ, Kraan MC, Baeten D, McInnes IB, Bresnihan B, Tak PP.

Ann Rheum Dis. 2005 Jun;64(6):834-8. Epub 2004 Dec 2.


The presence of citrullinated proteins is not specific for rheumatoid synovial tissue.

Vossenaar ER, Smeets TJ, Kraan MC, Raats JM, van Venrooij WJ, Tak PP.

Arthritis Rheum. 2004 Nov;50(11):3485-94.


Tumour necrosis factor alpha blockade in treatment resistant pigmented villonodular synovitis.

Kroot EJ, Kraan MC, Smeets TJ, Maas M, Tak PP, Wouters JM.

Ann Rheum Dis. 2005 Mar;64(3):497-9. Epub 2004 Aug 5.


Early effects of tumour necrosis factor alpha blockade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritis.

Goedkoop AY, Kraan MC, Teunissen MB, Picavet DI, de Rie MA, Bos JD, Tak PP.

Ann Rheum Dis. 2004 Jul;63(7):769-73.


Differential effects of leflunomide and methotrexate on cytokine production in rheumatoid arthritis.

Kraan MC, Smeets TJ, van Loon MJ, Breedveld FC, Dijkmans BA, Tak PP.

Ann Rheum Dis. 2004 Sep;63(9):1056-61. Epub 2004 Apr 28.


T cells, fibroblast-like synoviocytes, and granzyme B+ cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis.

Kraan MC, Haringman JJ, Weedon H, Barg EC, Smith MD, Ahern MJ, Smeets TJ, Breedveld FC, Tak PP.

Ann Rheum Dis. 2004 May;63(5):483-8.

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