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Items: 15


High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms.

Jeromin S, Haferlach T, Grossmann V, Alpermann T, Kowarsch A, Haferlach C, Kern W, Schnittger S.

Haematologica. 2013 Feb;98(2):e15-7. doi: 10.3324/haematol.2012.072538. Epub 2012 Aug 28. No abstract available.


Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases.

Schnittger S, Bacher U, Alpermann T, Reiter A, Ulke M, Dicker F, Eder C, Kohlmann A, Grossmann V, Kowarsch A, Kern W, Haferlach C, Haferlach T.

Haematologica. 2012 Dec;97(12):1890-4. doi: 10.3324/haematol.2012.065375. Epub 2012 Jun 24.


Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity.

Bacher U, Schnittger S, Macijewski K, Grossmann V, Kohlmann A, Alpermann T, Kowarsch A, Nadarajah N, Kern W, Haferlach C, Haferlach T.

Blood. 2012 May 17;119(20):4719-22. doi: 10.1182/blood-2011-12-395574. Epub 2012 Mar 22.


PhenomiR: microRNAs in human diseases and biological processes.

Ruepp A, Kowarsch A, Theis F.

Methods Mol Biol. 2012;822:249-60. doi: 10.1007/978-1-61779-427-8_17.


Landscape of TET2 mutations in acute myeloid leukemia.

Weissmann S, Alpermann T, Grossmann V, Kowarsch A, Nadarajah N, Eder C, Dicker F, Fasan A, Haferlach C, Haferlach T, Kern W, Schnittger S, Kohlmann A.

Leukemia. 2012 May;26(5):934-42. doi: 10.1038/leu.2011.326. Epub 2011 Nov 25.


MicroRNAs coordinately regulate protein complexes.

Sass S, Dietmann S, Burk UC, Brabletz S, Lutter D, Kowarsch A, Mayer KF, Brabletz T, Ruepp A, Theis FJ, Wang Y.

BMC Syst Biol. 2011 Aug 25;5:136. doi: 10.1186/1752-0509-5-136.


miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs.

Kowarsch A, Preusse M, Marr C, Theis FJ.

RNA. 2011 May;17(5):809-19. doi: 10.1261/rna.2474511. Epub 2011 Mar 25. Erratum in: RNA. 2012 May;18(5):1101.


Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation.

Jungraithmayr TC, Hofer K, Cochat P, Chernin G, Cortina G, Fargue S, Grimm P, Knueppel T, Kowarsch A, Neuhaus T, Pagel P, Pfeiffer KP, Schäfer F, Schönermarck U, Seeman T, Toenshoff B, Weber S, Winn MP, Zschocke J, Zimmerhackl LB.

J Am Soc Nephrol. 2011 Mar;22(3):579-85. doi: 10.1681/ASN.2010010029. Epub 2011 Feb 25.


Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets.

Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U.

Cancer Res. 2011 Feb 1;71(3):693-704. doi: 10.1158/0008-5472.CAN-10-2987. Epub 2010 Dec 2.


Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation.

Kowarsch A, Blöchl F, Bohl S, Saile M, Gretz N, Klingmüller U, Theis FJ.

BMC Bioinformatics. 2010 Nov 30;11:585. doi: 10.1186/1471-2105-11-585.


Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier.

Balluff B, Elsner M, Kowarsch A, Rauser S, Meding S, Schuhmacher C, Feith M, Herrmann K, Röcken C, Schmid RM, Höfler H, Walch A, Ebert MP.

J Proteome Res. 2010 Dec 3;9(12):6317-22. doi: 10.1021/pr100573s. Epub 2010 Nov 8.


MicroRNA loss enhances learning and memory in mice.

Konopka W, Kiryk A, Novak M, Herwerth M, Parkitna JR, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Theis FJ, Köhr G, Kaczmarek L, Schütz G.

J Neurosci. 2010 Nov 3;30(44):14835-42. doi: 10.1523/JNEUROSCI.3030-10.2010.


Correlated mutations: a hallmark of phenotypic amino acid substitutions.

Kowarsch A, Fuchs A, Frishman D, Pagel P.

PLoS Comput Biol. 2010 Sep 16;6(9). pii: e1000923. doi: 10.1371/journal.pcbi.1000923.


Tissue-specific target analysis of disease-associated microRNAs in human signaling pathways.

Kowarsch A, Marr C, Schmidl D, Ruepp A, Theis FJ.

PLoS One. 2010 Jun 30;5(6):e11154. doi: 10.1371/journal.pone.0011154.


PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.

Ruepp A, Kowarsch A, Schmidl D, Buggenthin F, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Theis FJ.

Genome Biol. 2010 Jan 20;11(1):R6. doi: 10.1186/gb-2010-11-1-r6.

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