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Results: 1 to 20 of 178

1.

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikäinen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai AT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J; CARe Consortium; COGENT Consortium, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polašek O, Wright AF, Griffin M, Daly MJ; DCCT/EDIC, Arnar DO, Hólm H, Thorsteinsdottir U; eMERGE Consortium, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O'Donnell CJ, Yin X, Bobbo M, D'Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jöckel KH, Kälsch H, Nöthen MM; HRGEN Consortium, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, Prucha H, Sinner MF, Waldenberger M, de Boer RA, Franke L, van der Vleuten PA, Beckmann BM, Martens E, Bardai A, Hofman N, Wilde AA, Behr ER, Dalageorgou C, Giudicessi JR, Medeiros-Domingo A, Barc J, Kyndt F, Probst V, Ghidoni A, Insolia R, Hamilton RM, Scherer SW, Brandimarto J, Margulies K, Moravec CE, Greco M FD, Fuchsberger C, O'Connell JR, Lee WK, Watt GC, Campbell H, Wild SH, El Mokhtari NE, Frey N, Asselbergs FW, Leach IM, Navis G, van den Berg MP, van Veldhuisen DJ, Kellis M, Krijthe BP, Franco OH, Hofman A, Kors JA, Uitterlinden AG, Witteman JC, Kedenko L, Lamina C, Oostra BA, Abecasis GR, Lakatta EG, Mulas A, Orrú M, Schlessinger D, Uda M, Markus MR, Völker U, Snieder H, Spector TD, Arnlöv J, Lind L, Sundström J, Syvänen AC, Kivimaki M, Kähönen M, Mononen N, Raitakari OT, Viikari JS, Adamkova V, Kiechl S, Brion M, Nicolaides AN, Paulweber B, Haerting J, Dominiczak AF, Nyberg F, Whincup PH, Hingorani AD, Schott JJ, Bezzina CR, Ingelsson E, Ferrucci L, Gasparini P, Wilson JF, Rudan I, Franke A, Mühleisen TW, Pramstaller PP, Lehtimäki TJ, Paterson AD, Parsa A, Liu Y, van Duijn CM, Siscovick DS, Gudnason V, Jamshidi Y, Salomaa V, Felix SB, Sanna S, Ritchie MD, Stricker BH, Stefansson K, Boyer LA, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C.

Nat Genet. 2014 Jun 22. doi: 10.1038/ng.3014. [Epub ahead of print]

PMID:
24952745
[PubMed - as supplied by publisher]
2.

Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study.

Medenwald D, Kors JA, Loppnow H, Thiery J, Kluttig A, Nuding S, Tiller D, Greiser KH, Werdan K, Haerting J.

PLoS One. 2014 Apr 25;9(4):e95994. doi: 10.1371/journal.pone.0095994. eCollection 2014.

PMID:
24770373
[PubMed - in process]
Free PMC Article
3.

Knowledge-based extraction of adverse drug events from biomedical text.

Kang N, Singh B, Bui C, Afzal Z, van Mulligen EM, Kors JA.

BMC Bioinformatics. 2014 Mar 4;15:64. doi: 10.1186/1471-2105-15-64.

PMID:
24593054
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Comparison of prognosis in unrecognized versus recognized myocardial infarction in men versus women >55 years of age (from the Rotterdam Study).

Dehghan A, Leening MJ, Solouki AM, Boersma E, Deckers JW, van Herpen G, Heeringa J, Hofman A, Kors JA, Franco OH, Ikram MA, Witteman JC.

Am J Cardiol. 2014 Jan 1;113(1):1-6. doi: 10.1016/j.amjcard.2013.09.005. Epub 2013 Oct 2.

PMID:
24216125
[PubMed - indexed for MEDLINE]
5.

Serum potassium levels and the risk of atrial fibrillation: the Rotterdam Study.

Krijthe BP, Heeringa J, Kors JA, Hofman A, Franco OH, Witteman JC, Stricker BH.

Int J Cardiol. 2013 Oct 15;168(6):5411-5. doi: 10.1016/j.ijcard.2013.08.048. Epub 2013 Aug 24.

PMID:
24012173
[PubMed - indexed for MEDLINE]
6.

Automatic detection of adverse events to predict drug label changes using text and data mining techniques.

Gurulingappa H, Toldo L, Rajput AM, Kors JA, Taweel A, Tayrouz Y.

Pharmacoepidemiol Drug Saf. 2013 Nov;22(11):1189-94. doi: 10.1002/pds.3493. Epub 2013 Aug 12.

PMID:
23935003
[PubMed - in process]
7.

Resting heart rate and the risk of heart failure in healthy adults: the Rotterdam Study.

Nanchen D, Leening MJ, Locatelli I, Cornuz J, Kors JA, Heeringa J, Deckers JW, Hofman A, Franco OH, Stricker BH, Witteman JC, Dehghan A.

Circ Heart Fail. 2013 May;6(3):403-10. doi: 10.1161/CIRCHEARTFAILURE.112.000171. Epub 2013 Apr 18.

PMID:
23599310
[PubMed - indexed for MEDLINE]
Free Article
8.

Automatic generation of case-detection algorithms to identify children with asthma from large electronic health record databases.

Afzal Z, Engelkes M, Verhamme KM, Janssens HM, Sturkenboom MC, Kors JA, Schuemie MJ.

Pharmacoepidemiol Drug Saf. 2013 Aug;22(8):826-33. doi: 10.1002/pds.3438. Epub 2013 Apr 17.

PMID:
23592573
[PubMed - indexed for MEDLINE]
9.

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L; Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ.

Nat Genet. 2013 Jun;45(6):621-31. doi: 10.1038/ng.2610. Epub 2013 Apr 14.

PMID:
23583979
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Prevalence of symptomatic heart failure with reduced and with normal ejection fraction in an elderly general population-the CARLA study.

Tiller D, Russ M, Greiser KH, Nuding S, Ebelt H, Kluttig A, Kors JA, Thiery J, Bruegel M, Haerting J, Werdan K.

PLoS One. 2013;8(3):e59225. doi: 10.1371/journal.pone.0059225. Epub 2013 Mar 15.

PMID:
23555000
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.

Avery CL, Sitlani CM, Arking DE, Arnett DK, Bis JC, Boerwinkle E, Buckley BM, Ida Chen YD, de Craen AJ, Eijgelsheim M, Enquobahrie D, Evans DS, Ford I, Garcia ME, Gudnason V, Harris TB, Heckbert SR, Hochner H, Hofman A, Hsueh WC, Isaacs A, Jukema JW, Knekt P, Kors JA, Krijthe BP, Kristiansson K, Laaksonen M, Liu Y, Li X, Macfarlane PW, Newton-Cheh C, Nieminen MS, Oostra BA, Peloso GM, Porthan K, Rice K, Rivadeneira FF, Rotter JI, Salomaa V, Sattar N, Siscovick DS, Slagboom PE, Smith AV, Sotoodehnia N, Stott DJ, Stricker BH, Stürmer T, Trompet S, Uitterlinden AG, van Duijn C, Westendorp RG, Witteman JC, Whitsel EA, Psaty BM.

Pharmacogenomics J. 2014 Feb;14(1):6-13. doi: 10.1038/tpj.2013.4. Epub 2013 Mar 5.

PMID:
23459443
[PubMed - in process]
12.

Improving sensitivity of machine learning methods for automated case identification from free-text electronic medical records.

Afzal Z, Schuemie MJ, van Blijderveen JC, Sen EF, Sturkenboom MC, Kors JA.

BMC Med Inform Decis Mak. 2013 Mar 2;13:30. doi: 10.1186/1472-6947-13-30.

PMID:
23452306
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease.

Warnier MJ, Rutten FH, Numans ME, Kors JA, Tan HL, de Boer A, Hoes AW, De Bruin ML.

COPD. 2013 Feb;10(1):62-71. doi: 10.3109/15412555.2012.727918.

PMID:
23413894
[PubMed - indexed for MEDLINE]
14.

Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data.

Hettne KM, Boorsma A, van Dartel DA, Goeman JJ, de Jong E, Piersma AH, Stierum RH, Kleinjans JC, Kors JA.

BMC Med Genomics. 2013 Jan 29;6:2. doi: 10.1186/1755-8794-6-2.

PMID:
23356878
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Unrecognized myocardial infarction and risk of atrial fibrillation: the Rotterdam Study.

Krijthe BP, Leening MJ, Heeringa J, Kors JA, Hofman A, Franco OH, Witteman JC, Stricker BH.

Int J Cardiol. 2013 Sep 30;168(2):1453-7. doi: 10.1016/j.ijcard.2012.12.057. Epub 2013 Jan 17.

PMID:
23332895
[PubMed - indexed for MEDLINE]
16.

Consistency of systematic chemical identifiers within and between small-molecule databases.

Akhondi SA, Kors JA, Muresan S.

J Cheminform. 2012 Dec 13;4(1):35. doi: 10.1186/1758-2946-4-35.

PMID:
23237381
[PubMed]
Free PMC Article
17.

The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.

Oliveira JL, Lopes P, Nunes T, Campos D, Boyer S, Ahlberg E, van Mulligen EM, Kors JA, Singh B, Furlong LI, Sanz F, Bauer-Mehren A, Carrascosa MC, Mestres J, Avillach P, Diallo G, Díaz Acedo C, van der Lei J.

Pharmacoepidemiol Drug Saf. 2013 May;22(5):459-67. doi: 10.1002/pds.3375. Epub 2012 Dec 4.

PMID:
23208789
[PubMed - indexed for MEDLINE]
18.

Using rule-based natural language processing to improve disease normalization in biomedical text.

Kang N, Singh B, Afzal Z, van Mulligen EM, Kors JA.

J Am Med Inform Assoc. 2013 Sep-Oct;20(5):876-81. doi: 10.1136/amiajnl-2012-001173. Epub 2012 Oct 6.

PMID:
23043124
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cardiac arrhythmias in adult patients with asthma.

Warnier MJ, Rutten FH, Kors JA, Lammers JW, de Boer A, Hoes AW, de Bruin ML.

J Asthma. 2012 Nov;49(9):942-6. doi: 10.3109/02770903.2012.724132. Epub 2012 Sep 27.

PMID:
23013453
[PubMed - indexed for MEDLINE]
20.

The EU-ADR corpus: annotated drugs, diseases, targets, and their relationships.

van Mulligen EM, Fourrier-Reglat A, Gurwitz D, Molokhia M, Nieto A, Trifiro G, Kors JA, Furlong LI.

J Biomed Inform. 2012 Oct;45(5):879-84. doi: 10.1016/j.jbi.2012.04.004. Epub 2012 Apr 25.

PMID:
22554700
[PubMed - indexed for MEDLINE]
Free Article

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