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Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.

Robinson PJ, Trnka MJ, Bushnell DA, Davis RE, Mattei PJ, Burlingame AL, Kornberg RD.

Cell. 2016 Sep 8;166(6):1411-1422.e16. doi: 10.1016/j.cell.2016.08.050.


Synthesis of Water-Soluble, Thiolate-Protected Gold Nanoparticles Uniform in Size.

Azubel M, Kornberg RD.

Nano Lett. 2016 May 11;16(5):3348-51. doi: 10.1021/acs.nanolett.6b00981. Epub 2016 Apr 19.


Stable Chromosome Condensation Revealed by Chromosome Conformation Capture.

Eagen KP, Hartl TA, Kornberg RD.

Cell. 2015 Nov 5;163(4):934-46. doi: 10.1016/j.cell.2015.10.026.


Chromatin-remodeling and the initiation of transcription.

Lorch Y, Kornberg RD.

Q Rev Biophys. 2015 Nov;48(4):465-70. doi: 10.1017/S0033583515000116. Review.


Structure of an RNA polymerase II preinitiation complex.

Murakami K, Tsai KL, Kalisman N, Bushnell DA, Asturias FJ, Kornberg RD.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13543-8. doi: 10.1073/pnas.1518255112. Epub 2015 Oct 19.


Molecular architecture of the yeast Mediator complex.

Robinson PJ, Trnka MJ, Pellarin R, Greenberg CH, Bushnell DA, Davis R, Burlingame AL, Sali A, Kornberg RD.

Elife. 2015 Sep 24;4. pii: e08719. doi: 10.7554/eLife.08719.


Real-time observation of the initiation of RNA polymerase II transcription.

Fazal FM, Meng CA, Murakami K, Kornberg RD, Block SM.

Nature. 2015 Sep 10;525(7568):274-7. doi: 10.1038/nature14882. Epub 2015 Sep 2.


Uncoupling Promoter Opening from Start-Site Scanning.

Murakami K, Mattei PJ, Davis RE, Jin H, Kaplan CD, Kornberg RD.

Mol Cell. 2015 Jul 2;59(1):133-8. doi: 10.1016/j.molcel.2015.05.021. Epub 2015 Jun 11.


Role of DNA sequence in chromatin remodeling and the formation of nucleosome-free regions.

Lorch Y, Maier-Davis B, Kornberg RD.

Genes Dev. 2014 Nov 15;28(22):2492-7. doi: 10.1101/gad.250704.114.


Nanoparticle imaging. Electron microscopy of gold nanoparticles at atomic resolution.

Azubel M, Koivisto J, Malola S, Bushnell D, Hura GL, Koh AL, Tsunoyama H, Tsukuda T, Pettersson M, Häkkinen H, Kornberg RD.

Science. 2014 Aug 22;345(6199):909-12. doi: 10.1126/science.1251959.


Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.

Schweikhard V, Meng C, Murakami K, Kaplan CD, Kornberg RD, Block SM.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6642-7. doi: 10.1073/pnas.1405181111. Epub 2014 Apr 14.


Architecture of an RNA polymerase II transcription pre-initiation complex.

Murakami K, Elmlund H, Kalisman N, Bushnell DA, Adams CM, Azubel M, Elmlund D, Levi-Kalisman Y, Liu X, Gibbons BJ, Levitt M, Kornberg RD.

Science. 2013 Nov 8;342(6159):1238724. doi: 10.1126/science.1238724. Epub 2013 Sep 26.


Formation and fate of a complete 31-protein RNA polymerase II transcription preinitiation complex.

Murakami K, Calero G, Brown CR, Liu X, Davis RE, Boeger H, Kornberg RD.

J Biol Chem. 2013 Mar 1;288(9):6325-32. doi: 10.1074/jbc.M112.433623. Epub 2013 Jan 9.


Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II.

Robinson PJ, Bushnell DA, Trnka MJ, Burlingame AL, Kornberg RD.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17931-5. doi: 10.1073/pnas.1215241109. Epub 2012 Oct 15.


RNA polymerase II transcription: structure and mechanism.

Liu X, Bushnell DA, Kornberg RD.

Biochim Biophys Acta. 2013 Jan;1829(1):2-8. doi: 10.1016/j.bbagrm.2012.09.003. Epub 2012 Sep 18. Review.


Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.

Larson MH, Zhou J, Kaplan CD, Palangat M, Kornberg RD, Landick R, Block SM.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6555-60. doi: 10.1073/pnas.1200939109. Epub 2012 Apr 9.


Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.

Murakami K, Gibbons BJ, Davis RE, Nagai S, Liu X, Robinson PJ, Wu T, Kaplan CD, Kornberg RD.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4816-21. doi: 10.1073/pnas.1201448109. Epub 2012 Mar 12.


Subunit architecture of general transcription factor TFIIH.

Gibbons BJ, Brignole EJ, Azubel M, Murakami K, Voss NR, Bushnell DA, Asturias FJ, Kornberg RD.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1949-54. doi: 10.1073/pnas.1105266109. Epub 2012 Jan 20.


Lock and key to transcription: σ-DNA interaction.

Liu X, Bushnell DA, Kornberg RD.

Cell. 2011 Dec 9;147(6):1218-9. doi: 10.1016/j.cell.2011.11.033.


Initiation complex structure and promoter proofreading.

Liu X, Bushnell DA, Silva DA, Huang X, Kornberg RD.

Science. 2011 Jul 29;333(6042):633-7. doi: 10.1126/science.1206629.

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