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Results: 1 to 20 of 215

1.

Network-based identification of feedback modules that control RhoA activity and cell migration.

Kim TH, Monsefi N, Song JH, von Kriegsheim A, Vandamme D, Pertz O, Kholodenko BN, Kolch W, Cho KH.

J Mol Cell Biol. 2015 Mar 16. pii: mjv017. [Epub ahead of print]

2.

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies.

Tortolina L, Duffy DJ, Maffei M, Castagnino N, Carmody AM, Kolch W, Kholodenko BN, De Ambrosi C, Barla A, Biganzoli EM, Nencioni A, Patrone F, Ballestrero A, Zoppoli G, Verri A, Parodi S.

Oncotarget. 2014 Dec 31. [Epub ahead of print]

3.

Signalling mechanisms regulating phenotypic changes in breast cancer cells.

Volinsky N, McCarthy CJ, Von Kriegsheim A, Saban N, Okada-Hatakeyama M, Kolch W, Kholodenko BN.

Biosci Rep. 2015 Feb 3. [Epub ahead of print]

4.

Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling device.

Nguyen LK, Matallanas DG, Romano D, Kholodenko BN, Kolch W.

Cell Cycle. 2015;14(2):189-99. doi: 10.4161/15384101.2014.973743.

PMID:
25607644
5.

Regulation of the MAPK pathway by raf kinase inhibitory protein.

Vandamme D, Herrero A, Al-Mulla F, Kolch W.

Crit Rev Oncog. 2014;19(6):405-15. Review.

PMID:
25597351
6.

Mechanochemical Stimulation of MCF7 Cells with Rod-Shaped Fe-Au Janus Particles Induces Cell Death Through Paradoxical Hyperactivation of ERK.

Kilinc D, Lesniak A, Rashdan SA, Gandhi D, Blasiak A, Fannin PC, von Kriegsheim A, Kolch W, Lee GU.

Adv Healthc Mater. 2015 Feb;4(3):395-404. doi: 10.1002/adhm.201400391. Epub 2014 Oct 9.

PMID:
25296863
7.

In vitro study of the interaction of heregulin-functionalized magnetic-optical nanorods with MCF7 and MDA-MB-231 cells.

Lesniak A, Kilinc D, Rashdan SA, von Kriegsheim A, Ashall B, Zerulla D, Kolch W, Lee GU.

Faraday Discuss. 2014;175:189-201. doi: 10.1039/c4fd00115j.

PMID:
25266763
8.

One Hippo and many masters: differential regulation of the Hippo pathway in cancer.

Romano D, Matallanas D, Frederick DT, Flaherty KT, Kolch W.

Biochem Soc Trans. 2014 Aug;42(4):816-21. doi: 10.1042/BST20140030.

PMID:
25109963
9.

Molecular mechanisms of asymmetric RAF dimer activation.

Jambrina PG, Bohuszewicz O, Buchete NV, Kolch W, Rosta E.

Biochem Soc Trans. 2014 Aug;42(4):784-90. doi: 10.1042/BST20140025.

PMID:
25109958
10.

Robustness and evolvability of the human signaling network.

Kim J, Vandamme D, Kim JR, Munoz AG, Kolch W, Cho KH.

PLoS Comput Biol. 2014 Jul 31;10(7):e1003763. doi: 10.1371/journal.pcbi.1003763. eCollection 2014 Jul.

11.

Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses.

Dobrzyński M, Nguyen LK, Birtwistle MR, von Kriegsheim A, Blanco Fernández A, Cheong A, Kolch W, Kholodenko BN.

J R Soc Interface. 2014 Sep 6;11(98):20140383. doi: 10.1098/rsif.2014.0383.

PMID:
24966234
12.

Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling.

Romano D, Nguyen LK, Matallanas D, Halasz M, Doherty C, Kholodenko BN, Kolch W.

Nat Cell Biol. 2014 Jul;16(7):673-84. doi: 10.1038/ncb2986. Epub 2014 Jun 15.

PMID:
24929361
13.

Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells.

Jiwaji M, Sandison ME, Reboud J, Stevenson R, Daly R, Barkess G, Faulds K, Kolch W, Graham D, Girolami MA, Cooper JM, Pitt AR.

PLoS One. 2014 Jun 13;9(6):e99458. doi: 10.1371/journal.pone.0099458. eCollection 2014.

14.

On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomics.

Turriziani B, Garcia-Munoz A, Pilkington R, Raso C, Kolch W, von Kriegsheim A.

Biology (Basel). 2014 Apr 16;3(2):320-32. doi: 10.3390/biology3020320.

15.

Mig-6 participates in the regulation of cell senescence and retinoblastoma protein phosphorylation.

Milewska M, Kolch W.

Cell Signal. 2014 Sep;26(9):1870-7. doi: 10.1016/j.cellsig.2014.05.003. Epub 2014 May 9.

PMID:
24815188
16.

HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.

Farrell J, Kelly C, Rauch J, Kida K, García-Muñoz A, Monsefi N, Turriziani B, Doherty C, Mehta JP, Matallanas D, Simpson JC, Kolch W, von Kriegsheim A.

J Proteome Res. 2014 Jun 6;13(6):2874-86. doi: 10.1021/pr5000285. Epub 2014 May 5.

PMID:
24766643
17.

The APC network regulates the removal of mutated cells from colonic crypts.

Song JH, Huels DJ, Ridgway RA, Sansom OJ, Kholodenko BN, Kolch W, Cho KH.

Cell Rep. 2014 Apr 10;7(1):94-103. doi: 10.1016/j.celrep.2014.02.043. Epub 2014 Mar 27.

18.

Basic fibroblast growth factor modifies the hypoxic response of human bone marrow stromal cells by ERK-mediated enhancement of HIF-1α activity.

Fábián Z, Ramadurai S, Shaw G, Nasheuer HP, Kolch W, Taylor C, Barry F.

Stem Cell Res. 2014 May;12(3):646-58. doi: 10.1016/j.scr.2014.02.007. Epub 2014 Mar 6.

19.

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development.

Shilo A, Ben Hur V, Denichenko P, Stein I, Pikarsky E, Rauch J, Kolch W, Zender L, Karni R.

RNA. 2014 Apr;20(4):505-15. doi: 10.1261/rna.042259.113. Epub 2014 Feb 26.

PMID:
24572810
20.

Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.

Santra T, Kolch W, Kholodenko BN.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003385. doi: 10.1371/journal.pcbi.1003385. eCollection 2014 Feb.

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