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Results: 1 to 20 of 210

1.

Mechanochemical Stimulation of MCF7 Cells with Rod-Shaped Fe-Au Janus Particles Induces Cell Death Through Paradoxical Hyperactivation of ERK.

Kilinc D, Lesniak A, Rashdan SA, Gandhi D, Blasiak A, Fannin PC, von Kriegsheim A, Kolch W, Lee GU.

Adv Healthc Mater. 2014 Oct 9. doi: 10.1002/adhm.201400391. [Epub ahead of print]

PMID:
25296863
[PubMed - as supplied by publisher]
2.

In vitro study of the interaction of heregulin-functionalized magnetic-optical nanorods with MCF7 and MDA-MB-231 cells.

Lesniak A, Kilinc D, Rashdan SA, von Kriegsheim A, Ashall B, Zerulla D, Kolch W, Lee GU.

Faraday Discuss. 2014 Sep 30. [Epub ahead of print]

PMID:
25266763
[PubMed - as supplied by publisher]
3.

One Hippo and many masters: differential regulation of the Hippo pathway in cancer.

Romano D, Matallanas D, Frederick DT, Flaherty KT, Kolch W.

Biochem Soc Trans. 2014 Aug;42(4):816-21. doi: 10.1042/BST20140030.

PMID:
25109963
[PubMed - in process]
4.

Molecular mechanisms of asymmetric RAF dimer activation.

Jambrina PG, Bohuszewicz O, Buchete NV, Kolch W, Rosta E.

Biochem Soc Trans. 2014 Aug;42(4):784-90. doi: 10.1042/BST20140025.

PMID:
25109958
[PubMed - in process]
5.

Robustness and evolvability of the human signaling network.

Kim J, Vandamme D, Kim JR, Munoz AG, Kolch W, Cho KH.

PLoS Comput Biol. 2014 Jul 31;10(7):e1003763. doi: 10.1371/journal.pcbi.1003763. eCollection 2014 Jul.

PMID:
25077791
[PubMed - in process]
Free PMC Article
6.

Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses.

Dobrzyński M, Nguyen LK, Birtwistle MR, von Kriegsheim A, Blanco Fernández A, Cheong A, Kolch W, Kholodenko BN.

J R Soc Interface. 2014 Sep 6;11(98):20140383. doi: 10.1098/rsif.2014.0383.

PMID:
24966234
[PubMed - in process]
7.

Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling.

Romano D, Nguyen LK, Matallanas D, Halasz M, Doherty C, Kholodenko BN, Kolch W.

Nat Cell Biol. 2014 Jul;16(7):673-84. doi: 10.1038/ncb2986. Epub 2014 Jun 15.

PMID:
24929361
[PubMed - indexed for MEDLINE]
8.

Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells.

Jiwaji M, Sandison ME, Reboud J, Stevenson R, Daly R, Barkess G, Faulds K, Kolch W, Graham D, Girolami MA, Cooper JM, Pitt AR.

PLoS One. 2014 Jun 13;9(6):e99458. doi: 10.1371/journal.pone.0099458. eCollection 2014.

PMID:
24926959
[PubMed - in process]
Free PMC Article
9.

On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomics.

Turriziani B, Garcia-Munoz A, Pilkington R, Raso C, Kolch W, von Kriegsheim A.

Biology (Basel). 2014 Apr 16;3(2):320-32. doi: 10.3390/biology3020320.

PMID:
24833512
[PubMed]
Free PMC Article
10.

Mig-6 participates in the regulation of cell senescence and retinoblastoma protein phosphorylation.

Milewska M, Kolch W.

Cell Signal. 2014 Sep;26(9):1870-7. doi: 10.1016/j.cellsig.2014.05.003. Epub 2014 May 9.

PMID:
24815188
[PubMed - in process]
11.

HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.

Farrell J, Kelly C, Rauch J, Kida K, García-Muñoz A, Monsefi N, Turriziani B, Doherty C, Mehta JP, Matallanas D, Simpson JC, Kolch W, von Kriegsheim A.

J Proteome Res. 2014 Jun 6;13(6):2874-86. doi: 10.1021/pr5000285. Epub 2014 May 5.

PMID:
24766643
[PubMed - in process]
12.

The APC network regulates the removal of mutated cells from colonic crypts.

Song JH, Huels DJ, Ridgway RA, Sansom OJ, Kholodenko BN, Kolch W, Cho KH.

Cell Rep. 2014 Apr 10;7(1):94-103. doi: 10.1016/j.celrep.2014.02.043. Epub 2014 Mar 27.

PMID:
24685131
[PubMed - in process]
Free Article
13.

Basic fibroblast growth factor modifies the hypoxic response of human bone marrow stromal cells by ERK-mediated enhancement of HIF-1α activity.

Fábián Z, Ramadurai S, Shaw G, Nasheuer HP, Kolch W, Taylor C, Barry F.

Stem Cell Res. 2014 May;12(3):646-58. doi: 10.1016/j.scr.2014.02.007. Epub 2014 Mar 6.

PMID:
24667757
[PubMed - in process]
Free Article
14.

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development.

Shilo A, Ben Hur V, Denichenko P, Stein I, Pikarsky E, Rauch J, Kolch W, Zender L, Karni R.

RNA. 2014 Apr;20(4):505-15. doi: 10.1261/rna.042259.113. Epub 2014 Feb 26.

PMID:
24572810
[PubMed - indexed for MEDLINE]
15.

Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.

Santra T, Kolch W, Kholodenko BN.

PLoS Comput Biol. 2014 Feb 13;10(2):e1003385. doi: 10.1371/journal.pcbi.1003385. eCollection 2014 Feb.

PMID:
24550716
[PubMed - in process]
Free PMC Article
16.

Evaluating strategies to normalise biological replicates of Western blot data.

Degasperi A, Birtwistle MR, Volinsky N, Rauch J, Kolch W, Kholodenko BN.

PLoS One. 2014 Jan 27;9(1):e87293. doi: 10.1371/journal.pone.0087293. eCollection 2014.

PMID:
24475266
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

GSK3 inhibitors regulate MYCN mRNA levels and reduce neuroblastoma cell viability through multiple mechanisms, including p53 and Wnt signaling.

Duffy DJ, Krstic A, Schwarzl T, Higgins DG, Kolch W.

Mol Cancer Ther. 2014 Feb;13(2):454-67. doi: 10.1158/1535-7163.MCT-13-0560-T. Epub 2013 Nov 26.

PMID:
24282277
[PubMed - in process]
18.

Systems biology-embedded target validation: improving efficacy in drug discovery.

Vandamme D, Minke BA, Fitzmaurice W, Kholodenko BN, Kolch W.

Wiley Interdiscip Rev Syst Biol Med. 2014 Jan-Feb;6(1):1-11. doi: 10.1002/wsbm.1253. Epub 2013 Nov 8.

PMID:
24214316
[PubMed - indexed for MEDLINE]
19.

Systems medicine: opportunities and challenges for systems biology approaches.

Kolch W, Kholodenko BN.

FEBS J. 2013 Dec;280(23):5937. doi: 10.1111/febs.12560. Epub 2013 Oct 30.

PMID:
24128262
[PubMed - indexed for MEDLINE]
20.

Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity.

von Thun A, Preisinger C, Rath O, Schwarz JP, Ward C, Monsefi N, Rodríguez J, Garcia-Munoz A, Birtwistle M, Bienvenut W, Anderson KI, Kolch W, von Kriegsheim A.

Mol Cell Biol. 2013 Nov;33(22):4526-37. doi: 10.1128/MCB.00585-13. Epub 2013 Sep 16.

PMID:
24043311
[PubMed - indexed for MEDLINE]
Free PMC Article

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