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Results: 16

1.

Studying SIRT6 regulation using H3K56 based substrate and small molecules.

Kokkonen P, Rahnasto-Rilla M, Mellini P, Jarho E, Lahtela-Kakkonen M, Kokkola T.

Eur J Pharm Sci. 2014 Jul 6;63C:71-76. doi: 10.1016/j.ejps.2014.06.015. [Epub ahead of print]

PMID:
25004411
[PubMed - as supplied by publisher]
2.

AROS has a context-dependent effect on SIRT1.

Kokkola T, Suuronen T, Molnár F, Määttä J, Salminen A, Jarho EM, Lahtela-Kakkonen M.

FEBS Lett. 2014 May 2;588(9):1523-8. doi: 10.1016/j.febslet.2014.03.020. Epub 2014 Mar 26.

PMID:
24681097
[PubMed - indexed for MEDLINE]
3.

Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells.

Mellini P, Kokkola T, Suuronen T, Salo HS, Tolvanen L, Mai A, Lahtela-Kakkonen M, Jarho EM.

J Med Chem. 2013 Sep 12;56(17):6681-95. doi: 10.1021/jm400438k. Epub 2013 Aug 22.

PMID:
23927550
[PubMed - indexed for MEDLINE]
4.

Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase.

Kokkola T, Kruse C, Roy-Pogodzik EM, Pekkinen J, Bauch C, Hönck HH, Hennemann H, Kreienkamp HJ.

FEBS Lett. 2011 Sep 2;585(17):2665-70. doi: 10.1016/j.febslet.2011.07.028. Epub 2011 Jul 31.

PMID:
21820437
[PubMed - indexed for MEDLINE]
Free Article
5.

Treatments with sodium selenate or doxycycline offset diabetes-induced perturbations of thioredoxin-1 levels and antioxidant capacity.

Atalay M, Bilginoglu A, Kokkola T, Oksala N, Turan B.

Mol Cell Biochem. 2011 May;351(1-2):125-31. doi: 10.1007/s11010-011-0719-3. Epub 2011 Jan 19.

PMID:
21246260
[PubMed - indexed for MEDLINE]
6.

An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples.

Breusing N, Grune T, Andrisic L, Atalay M, Bartosz G, Biasi F, Borovic S, Bravo L, Casals I, Casillas R, Dinischiotu A, Drzewinska J, Faber H, Fauzi NM, Gajewska A, Gambini J, Gradinaru D, Kokkola T, Lojek A, Luczaj W, Margina D, Mascia C, Mateos R, Meinitzer A, Mitjavila MT, Mrakovcic L, Munteanu MC, Podborska M, Poli G, Sicinska P, Skrzydlewska E, Vina J, Wiswedel I, Zarkovic N, Zelzer S, Spickett CM.

Free Radic Res. 2010 Oct;44(10):1203-15. doi: 10.3109/10715762.2010.499907.

PMID:
20836662
[PubMed - indexed for MEDLINE]
7.

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

Kokkola T, Vaittinen M, Laitinen JT.

J Pineal Res. 2007 Oct;43(3):255-62.

PMID:
17803522
[PubMed - indexed for MEDLINE]
8.

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

Kokkola T, Salo OM, Poso A, Laitinen JT.

J Pineal Res. 2005 Aug;39(1):1-11.

PMID:
15978051
[PubMed - indexed for MEDLINE]
9.

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor.

Savinainen JR, Kokkola T, Salo OM, Poso A, Järvinen T, Laitinen JT.

Br J Pharmacol. 2005 Jul;145(5):636-45.

PMID:
15852035
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

S-nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.

Kokkola T, Savinainen JR, Mönkkönen KS, Retamal MD, Laitinen JT.

BMC Cell Biol. 2005 Apr 25;6(1):21.

PMID:
15850493
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Important amino acids for the function of the human MT1 melatonin receptor.

Kokkola T, Foord SM, Watson MA, Vakkuri O, Laitinen JT.

Biochem Pharmacol. 2003 May 1;65(9):1463-71.

PMID:
12732358
[PubMed - indexed for MEDLINE]
12.

Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function.

Kokkola T, Watson MA, White J, Dowell S, Foord SM, Laitinen JT.

Biochem Biophys Res Commun. 1998 Aug 19;249(2):531-6.

PMID:
9712731
[PubMed - indexed for MEDLINE]
13.

Melatonin receptor genes.

Kokkola T, Laitinen JT.

Ann Med. 1998 Feb;30(1):88-94. Review.

PMID:
9556094
[PubMed - indexed for MEDLINE]
14.

A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor.

Navajas C, Kokkola T, Poso A, Honka N, Gynther J, Laitinen JT.

Eur J Pharmacol. 1996 May 23;304(1-3):173-83.

PMID:
8813600
[PubMed - indexed for MEDLINE]
15.

Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat.

Pohjanvirta R, Laitinen Jt, Vakkuri O, Lindén J, Kokkola T, Unkila M, Tuomisto J.

Toxicology. 1996 Feb 22;107(2):85-97.

PMID:
8599175
[PubMed - indexed for MEDLINE]
16.

Cholinergic signaling in the rat pineal gland.

Laitinen JT, Laitinen KS, Kokkola T.

Cell Mol Neurobiol. 1995 Apr;15(2):177-92. Review.

PMID:
8590450
[PubMed - indexed for MEDLINE]

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