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Results: 1 to 20 of 94


The TRIM-NHL protein Brat promotes axon maintenance by repressing src64B expression.

Marchetti G, Reichardt I, Knoblich JA, Besse F.

J Neurosci. 2014 Oct 8;34(41):13855-64. doi: 10.1523/JNEUROSCI.3285-13.2014.


Generation of cerebral organoids from human pluripotent stem cells.

Lancaster MA, Knoblich JA.

Nat Protoc. 2014 Oct;9(10):2329-40. doi: 10.1038/nprot.2014.158. Epub 2014 Sep 4.


Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells.

Homem CC, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA.

Cell. 2014 Aug 14;158(4):874-88. doi: 10.1016/j.cell.2014.06.024.


The conserved discs-large binding partner Banderuola regulates asymmetric cell division in Drosophila.

Mauri F, Reichardt I, Mummery-Widmer JL, Yamazaki M, Knoblich JA.

Curr Biol. 2014 Aug 18;24(16):1811-25. doi: 10.1016/j.cub.2014.06.059. Epub 2014 Jul 31.


Organogenesis in a dish: modeling development and disease using organoid technologies.

Lancaster MA, Knoblich JA.

Science. 2014 Jul 18;345(6194):1247125. doi: 10.1126/science.1247125. Epub 2014 Jul 17. Review.


Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN.

Williams SE, Ratliff LA, Postiglione MP, Knoblich JA, Fuchs E.

Nat Cell Biol. 2014 Aug;16(8):758-69. doi: 10.1038/ncb3001. Epub 2014 Jul 13.


Dachsous-dependent asymmetric localization of spiny-legs determines planar cell polarity orientation in Drosophila.

Ayukawa T, Akiyama M, Mummery-Widmer JL, Stoeger T, Sasaki J, Knoblich JA, Senoo H, Sasaki T, Yamazaki M.

Cell Rep. 2014 Jul 24;8(2):610-21. doi: 10.1016/j.celrep.2014.06.009. Epub 2014 Jul 3.


A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells.

Yasugi T, Fischer A, Jiang Y, Reichert H, Knoblich JA.

PLoS One. 2014 May 7;9(5):e97034. doi: 10.1371/journal.pone.0097034. eCollection 2014.


SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells.

Eroglu E, Burkard TR, Jiang Y, Saini N, Homem CC, Reichert H, Knoblich JA.

Cell. 2014 Mar 13;156(6):1259-73. doi: 10.1016/j.cell.2014.01.053.


A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C.

Development. 2014 Feb;141(3):604-16. doi: 10.1242/dev.100487.


Analysis and modeling of mitotic spindle orientations in three dimensions.

Jüschke C, Xie Y, Postiglione MP, Knoblich JA.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1014-9. doi: 10.1073/pnas.1314984111. Epub 2013 Dec 31.


Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

Jüschke C, Dohnal I, Pichler P, Harzer H, Swart R, Ammerer G, Mechtler K, Knoblich JA.

Genome Biol. 2013 Nov 30;14(11):r133. doi: 10.1186/gb-2013-14-11-r133.


Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages.

Homem CC, Reichardt I, Berger C, Lendl T, Knoblich JA.

PLoS One. 2013 Nov 8;8(11):e79588. doi: 10.1371/journal.pone.0079588. eCollection 2013.


Cerebral organoids model human brain development and microcephaly.

Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA.

Nature. 2013 Sep 19;501(7467):373-9. doi: 10.1038/nature12517. Epub 2013 Aug 28.


Identification of transcription factor binding sites from ChIP-seq data at high resolution.

Bardet AF, Steinmann J, Bafna S, Knoblich JA, Zeitlinger J, Stark A.

Bioinformatics. 2013 Nov 1;29(21):2705-13. doi: 10.1093/bioinformatics/btt470. Epub 2013 Aug 24.


The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex.

Xie Y, Jüschke C, Esk C, Hirotsune S, Knoblich JA.

Neuron. 2013 Jul 24;79(2):254-65. doi: 10.1016/j.neuron.2013.05.027. Epub 2013 Jul 3.


FACS purification of Drosophila larval neuroblasts for next-generation sequencing.

Harzer H, Berger C, Conder R, Schmauss G, Knoblich JA.

Nat Protoc. 2013 Jun;8(6):1088-99. doi: 10.1038/nprot.2013.062. Epub 2013 May 9.


The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.

Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, Hulsman D, Mann M, Knoblich JA, van Lohuizen M.

EMBO J. 2013 May 29;32(11):1598-612. doi: 10.1038/emboj.2013.93. Epub 2013 Apr 26.


Cell biology: Notch recycling is numbed.

Reichardt I, Knoblich JA.

Curr Biol. 2013 Apr 8;23(7):R270-2. doi: 10.1016/j.cub.2013.03.013.


Drosophila neuroblasts: a model for stem cell biology.

Homem CC, Knoblich JA.

Development. 2012 Dec 1;139(23):4297-310. doi: 10.1242/dev.080515. Review.

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