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Results: 1 to 20 of 38

1.

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.

Basters A, Geurink PP, El Oualid F, Ketscher L, Casutt MS, Krause E, Ovaa H, Knobeloch KP, Fritz G.

FEBS J. 2014 Apr;281(7):1918-28. doi: 10.1111/febs.12754. Epub 2014 Mar 3.

PMID:
24533902
[PubMed - indexed for MEDLINE]
2.

STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.

Begitt A, Droescher M, Meyer T, Schmid CD, Baker M, Antunes F, Knobeloch KP, Owen MR, Naumann R, Decker T, Vinkemeier U.

Nat Immunol. 2014 Feb;15(2):168-76. doi: 10.1038/ni.2794. Epub 2014 Jan 12.

PMID:
24413774
[PubMed - indexed for MEDLINE]
3.

HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia.

Troilo A, Alexander I, Muehl S, Jaramillo D, Knobeloch KP, Krek W.

EMBO Rep. 2014 Jan;15(1):77-85. doi: 10.1002/embr.201337688. Epub 2013 Dec 30.

PMID:
24378640
[PubMed - in process]
Free Article
4.

ISG15 regulates peritoneal macrophages functionality against viral infection.

Yángüez E, García-Culebras A, Frau A, Llompart C, Knobeloch KP, Gutierrez-Erlandsson S, García-Sastre A, Esteban M, Nieto A, Guerra S.

PLoS Pathog. 2013;9(10):e1003632. doi: 10.1371/journal.ppat.1003632. Epub 2013 Oct 10. Erratum in: PLoS Pathog. 2013 Oct;9(10). doi: 10.1371/annotation/64a20cef-bf55-4d84-983e-b914eb09b1ee.

PMID:
24137104
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system.

Basters A, Ketscher L, Deuerling E, Arkona C, Rademann J, Knobeloch KP, Fritz G.

BMC Biotechnol. 2012 Aug 23;12:56. doi: 10.1186/1472-6750-12-56.

PMID:
22916876
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Type I interferons as ambiguous modulators of chronic inflammation in the central nervous system.

Prinz M, Knobeloch KP.

Front Immunol. 2012 Apr 9;3:67. doi: 10.3389/fimmu.2012.00067. eCollection 2012.

PMID:
22566948
[PubMed]
Free PMC Article
7.

mHERC6 is the essential ISG15 E3 ligase in the murine system.

Ketscher L, Basters A, Prinz M, Knobeloch KP.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):135-40. doi: 10.1016/j.bbrc.2011.11.071. Epub 2011 Nov 23.

PMID:
22138649
[PubMed - indexed for MEDLINE]
8.

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.

Dann A, Poeck H, Croxford AL, Gaupp S, Kierdorf K, Knust M, Pfeifer D, Maihoefer C, Endres S, Kalinke U, Meuth SG, Wiendl H, Knobeloch KP, Akira S, Waisman A, Hartmann G, Prinz M.

Nat Neurosci. 2011 Dec 4;15(1):98-106. doi: 10.1038/nn.2964.

PMID:
22138643
[PubMed - indexed for MEDLINE]
9.

ISG15 modulates development of the erythroid lineage.

Maragno AL, Pironin M, Alcalde H, Cong X, Knobeloch KP, Tangy F, Zhang DE, Ghysdael J, Quang CT.

PLoS One. 2011;6(10):e26068. doi: 10.1371/journal.pone.0026068. Epub 2011 Oct 12.

PMID:
22022510
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ.

Begitt A, Droescher M, Knobeloch KP, Vinkemeier U.

Blood. 2011 Jul 28;118(4):1002-7. doi: 10.1182/blood-2011-04-347930. Epub 2011 Jun 2.

PMID:
21636857
[PubMed - indexed for MEDLINE]
Free Article
11.

Control of bone formation by the serpentine receptor Frizzled-9.

Albers J, Schulze J, Beil FT, Gebauer M, Baranowsky A, Keller J, Marshall RP, Wintges K, Friedrich FW, Priemel M, Schilling AF, Rueger JM, Cornils K, Fehse B, Streichert T, Sauter G, Jakob F, Insogna KL, Pober B, Knobeloch KP, Francke U, Amling M, Schinke T.

J Cell Biol. 2011 Mar 21;192(6):1057-72. doi: 10.1083/jcb.201008012. Epub 2011 Mar 14.

PMID:
21402791
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system.

Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Del Turco D, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M.

Brain. 2011 Apr;134(Pt 4):1184-98. doi: 10.1093/brain/awq359. Epub 2011 Feb 10.

PMID:
21310728
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

In vivo functions of isgylation.

Knobeloch KP.

Subcell Biochem. 2010;54:215-27. doi: 10.1007/978-1-4419-6676-6_17.

PMID:
21222285
[PubMed - in process]
14.

Cone versus rod disease in a mutant Rpgr mouse caused by different genetic backgrounds.

Brunner S, Skosyrski S, Kirschner-Schwabe R, Knobeloch KP, Neidhardt J, Feil S, Glaus E, Luhmann UF, Rüther K, Berger W.

Invest Ophthalmol Vis Sci. 2010 Feb;51(2):1106-15. doi: 10.1167/iovs.08-2742. Epub 2009 Dec 10.

PMID:
20007830
[PubMed - indexed for MEDLINE]
Free Article
15.

Vaccinia virus E3 protein prevents the antiviral action of ISG15.

Guerra S, Cáceres A, Knobeloch KP, Horak I, Esteban M.

PLoS Pathog. 2008 Jul 4;4(7):e1000096. doi: 10.1371/journal.ppat.1000096.

PMID:
18604270
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system.

Prinz M, Schmidt H, Mildner A, Knobeloch KP, Hanisch UK, Raasch J, Merkler D, Detje C, Gutcher I, Mages J, Lang R, Martin R, Gold R, Becher B, Brück W, Kalinke U.

Immunity. 2008 May;28(5):675-86. doi: 10.1016/j.immuni.2008.03.011.

PMID:
18424188
[PubMed - indexed for MEDLINE]
Free Article
17.

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo.

Niendorf S, Oksche A, Kisser A, Löhler J, Prinz M, Schorle H, Feller S, Lewitzky M, Horak I, Knobeloch KP.

Mol Cell Biol. 2007 Jul;27(13):5029-39. Epub 2007 Apr 23.

PMID:
17452457
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.

Fischer A, Steidl C, Wagner TU, Lang E, Jakob PM, Friedl P, Knobeloch KP, Gessler M.

Circ Res. 2007 Mar 30;100(6):856-63. Epub 2007 Feb 15.

PMID:
17303760
[PubMed - indexed for MEDLINE]
Free Article
19.

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.

Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW 4th.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1371-6. Epub 2007 Jan 16.

PMID:
17227866
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

Lu G, Reinert JT, Pitha-Rowe I, Okumura A, Kellum M, Knobeloch KP, Hassel B, Pitha PM.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):29-41.

PMID:
16914094
[PubMed - indexed for MEDLINE]

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