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The Priority position paper: Protecting Europe's food chain from prions.

Requena JR, Kristensson K, Korth C, Zurzolo C, Simmons M, Aguilar-Calvo P, Aguzzi A, Andreoletti O, Benestad SL, Böhm R, Brown K, Calgua B, Del Río JA, Espinosa JC, Girones R, Godsave S, Hoelzle LE, Knittler MR, Kuhn F, Legname G, Laeven P, Mabbott N, Mitrova E, Müller-Schiffmann A, Nuvolone M, Peters PJ, Raeber A, Roth K, Schmitz M, Schroeder B, Sonati T, Stitz L, Taraboulos A, Torres JM, Yan ZX, Zerr I.

Prion. 2016 May 3;10(3):165-81. doi: 10.1080/19336896.2016.1175801.


Hydrophobic Interactions Are Key To Drive the Association of Tapasin with Peptide Transporter Subunit TAP2.

Rufer E, Kägebein D, Leonhardt RM, Knittler MR.

J Immunol. 2015 Dec 1;195(11):5482-94. doi: 10.4049/jimmunol.1500246. Epub 2015 Oct 30.


Chlamydia psittaci: update on an underestimated zoonotic agent.

Knittler MR, Sachse K.

Pathog Dis. 2015 Feb;73(1):1-15. doi: 10.1093/femspd/ftu007. Epub 2014 Dec 4. Review.


Chlamydia psittaci: new insights into genomic diversity, clinical pathology, host-pathogen interaction and anti-bacterial immunity.

Knittler MR, Berndt A, Böcker S, Dutow P, Hänel F, Heuer D, Kägebein D, Klos A, Koch S, Liebler-Tenorio E, Ostermann C, Reinhold P, Saluz HP, Schöfl G, Sehnert P, Sachse K.

Int J Med Microbiol. 2014 Oct;304(7):877-93. doi: 10.1016/j.ijmm.2014.06.010. Epub 2014 Jun 28. Review.


Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.

Kägebein D, Gutjahr M, Große C, Vogel AB, Rödel J, Knittler MR.

Infect Immun. 2014 Mar;82(3):993-1006. doi: 10.1128/IAI.01473-13. Epub 2013 Dec 16.


Amphisomal route of MHC class I cross-presentation in bacteria-infected dendritic cells.

Fiegl D, Kägebein D, Liebler-Tenorio EM, Weisser T, Sens M, Gutjahr M, Knittler MR.

J Immunol. 2013 Mar 15;190(6):2791-806. doi: 10.4049/jimmunol.1202741. Epub 2013 Feb 15.


Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi.

Rohde J, Emschermann F, Knittler MR, Rziha HJ.

BMC Vet Res. 2012 Jul 18;8:114. doi: 10.1186/1746-6148-8-114.


Identification of key amino acid residues that determine the ability of high risk HPV16-E7 to dysregulate major histocompatibility complex class I expression.

Heller C, Weisser T, Mueller-Schickert A, Rufer E, Hoh A, Leonhardt RM, Knittler MR.

J Biol Chem. 2011 Apr 1;286(13):10983-97. doi: 10.1074/jbc.M110.199190. Epub 2011 Feb 14.


Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.

Leonhardt RM, Fiegl D, Rufer E, Karger A, Bettin B, Knittler MR.

J Immunol. 2010 Mar 15;184(6):2985-98. doi: 10.4049/jimmunol.0900308. Epub 2010 Feb 17.


The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex.

Verweij MC, Koppers-Lalic D, Loch S, Klauschies F, de la Salle H, Quinten E, Lehner PJ, Mulder A, Knittler MR, Tampé R, Koch J, Ressing ME, Wiertz EJ.

J Immunol. 2008 Oct 1;181(7):4894-907.


Molecular architecture of the TAP-associated MHC class I peptide-loading complex.

Rufer E, Leonhardt RM, Knittler MR.

J Immunol. 2007 Nov 1;179(9):5717-27.


Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2.

Keusekotten K, Leonhardt RM, Ehses S, Knittler MR.

J Biol Chem. 2006 Jun 30;281(26):17545-51. Epub 2006 Apr 19.


Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex.

Leonhardt RM, Keusekotten K, Bekpen C, Knittler MR.

J Immunol. 2005 Oct 15;175(8):5104-14.


Functional role of C-terminal sequence elements in the transporter associated with antigen processing.

Ehses S, Leonhardt RM, Hansen G, Knittler MR.

J Immunol. 2005 Jan 1;174(1):328-39.


Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle.

Alberts P, Daumke O, Deverson EV, Howard JC, Knittler MR.

Curr Biol. 2001 Feb 20;11(4):242-51.


Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules.

Knittler MR, Alberts P, Deverson EV, Howard JC.

Curr Biol. 1999 Sep 23;9(18):999-1008.

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