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Items: 1 to 20 of 21


Hydrophobic Interactions Are Key To Drive the Association of Tapasin with Peptide Transporter Subunit TAP2.

Rufer E, Kägebein D, Leonhardt RM, Knittler MR.

J Immunol. 2015 Dec 1;195(11):5482-94. doi: 10.4049/jimmunol.1500246. Epub 2015 Oct 30.


Chlamydia psittaci: update on an underestimated zoonotic agent.

Knittler MR, Sachse K.

Pathog Dis. 2015 Feb;73(1):1-15. doi: 10.1093/femspd/ftu007. Epub 2014 Dec 4. Review.


Chlamydia psittaci: new insights into genomic diversity, clinical pathology, host-pathogen interaction and anti-bacterial immunity.

Knittler MR, Berndt A, Böcker S, Dutow P, Hänel F, Heuer D, Kägebein D, Klos A, Koch S, Liebler-Tenorio E, Ostermann C, Reinhold P, Saluz HP, Schöfl G, Sehnert P, Sachse K.

Int J Med Microbiol. 2014 Oct;304(7):877-93. doi: 10.1016/j.ijmm.2014.06.010. Epub 2014 Jun 28. Review.


Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.

Kägebein D, Gutjahr M, Große C, Vogel AB, Rödel J, Knittler MR.

Infect Immun. 2014 Mar;82(3):993-1006. doi: 10.1128/IAI.01473-13. Epub 2013 Dec 16.


Amphisomal route of MHC class I cross-presentation in bacteria-infected dendritic cells.

Fiegl D, Kägebein D, Liebler-Tenorio EM, Weisser T, Sens M, Gutjahr M, Knittler MR.

J Immunol. 2013 Mar 15;190(6):2791-806. doi: 10.4049/jimmunol.1202741. Epub 2013 Feb 15.


Orf virus interferes with MHC class I surface expression by targeting vesicular transport and Golgi.

Rohde J, Emschermann F, Knittler MR, Rziha HJ.

BMC Vet Res. 2012 Jul 18;8:114. doi: 10.1186/1746-6148-8-114.


Identification of key amino acid residues that determine the ability of high risk HPV16-E7 to dysregulate major histocompatibility complex class I expression.

Heller C, Weisser T, Mueller-Schickert A, Rufer E, Hoh A, Leonhardt RM, Knittler MR.

J Biol Chem. 2011 Apr 1;286(13):10983-97. doi: 10.1074/jbc.M110.199190. Epub 2011 Feb 14.


Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.

Leonhardt RM, Fiegl D, Rufer E, Karger A, Bettin B, Knittler MR.

J Immunol. 2010 Mar 15;184(6):2985-98. doi: 10.4049/jimmunol.0900308. Epub 2010 Feb 17.


The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex.

Verweij MC, Koppers-Lalic D, Loch S, Klauschies F, de la Salle H, Quinten E, Lehner PJ, Mulder A, Knittler MR, Tampé R, Koch J, Ressing ME, Wiertz EJ.

J Immunol. 2008 Oct 1;181(7):4894-907.


Molecular architecture of the TAP-associated MHC class I peptide-loading complex.

Rufer E, Leonhardt RM, Knittler MR.

J Immunol. 2007 Nov 1;179(9):5717-27.


Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2.

Keusekotten K, Leonhardt RM, Ehses S, Knittler MR.

J Biol Chem. 2006 Jun 30;281(26):17545-51. Epub 2006 Apr 19.


Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex.

Leonhardt RM, Keusekotten K, Bekpen C, Knittler MR.

J Immunol. 2005 Oct 15;175(8):5104-14.


Functional role of C-terminal sequence elements in the transporter associated with antigen processing.

Ehses S, Leonhardt RM, Hansen G, Knittler MR.

J Immunol. 2005 Jan 1;174(1):328-39.


Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle.

Alberts P, Daumke O, Deverson EV, Howard JC, Knittler MR.

Curr Biol. 2001 Feb 20;11(4):242-51.


Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules.

Knittler MR, Alberts P, Deverson EV, Howard JC.

Curr Biol. 1999 Sep 23;9(18):999-1008.

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